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Tag: "scan" at biology news

Research team identifies new Alzheimer's gene

...seven organizations contributed to the genome-wide scan using Affymetrix microarray technology. The team screened the DNA from 1,400 individuals who had been clinically assessed with Alzheimer’s prior death, and simultaneously examined more than 500,000 SNPs or genetic variations to characterize and confi...

CT scan reveals ancient long-necked gliding reptile

...bably lived in trees. The resolution of the CT scan is largely dependent on the size of the object to ...h the fossil specimens and the image data from the scan are preserved and can be reviewed and reanalyzed in the future. The scans presented to Fraser wer...

Gene therapy study shows safety and statistically significant improvement in Parkinson's disease

...ucose utilization as measured by PET scan. The PET scan data revealed a significant improvement (p<0.001) in brain metabolism on the treated side of the brain compared to the untreated side. No adverse events related to the gene therapy procedure were reported throughout the duration of the 12-month s...

Catching cancer's spread by watching hemoglobin

...p out the hemoglobin distribution, the researchers scan laser beams across the sample, a process that then reveals the outlines and contours of blood vessels. By taking images at different depths and stacking these images layer by layer, the researchers can reconstruct 3-D images of blood vessels. A ...

Genetic roots of bipolar disorder revealed by first genome-wide study of illness

...MH Genetics Initiative. The study is the first to scan virtually all of the variations in human genes to ...ipolar disorder, the U.S. researchers were able to scan the entire group at a small fraction of the cost of scanning each person's material individually. T...

World's leading scientists announce creation of 'Encyclopedia of Life'

...s most of the relevant scientific literature, will scan and digitize tens of millions of pages of the scientific literature that will offer open access to detailed knowledge. In fact, the BHL now has scanning centers operating in London, Boston, and Washington DC, and has scanned the first 1.25 million p...

Decoding protein structures helps illuminate cause of diabetes

...e current study, they obtained a single structural scan of hIAPP in less than a second - more than 500 times faster than previously possible. The speed is crucial for trying to understand a dynamic process like hIAPP mis-folding, Zanni says. The group now plans to capture series of snapshots durin...

Stanford-led study closes in on genes that may predispose some people to severe depression

... life. The first of the studies was a genome-wide scan that looked for evidence of genetic "linkage" within families between depression and DNA markers on the various chromosomes. The linkage study identified regions worthy of more intensive examination. The second study was a more detailed look at...

MIT model helps researchers 'see' brain development

...hanges over time and space. The original brain scan is then represented computationally with points. Charting each baby's brain requires about 130,000 points per hemisphere. Yu decomposed these points into a representation using just 42 points that shows only the coarsest folds. By adding more points,...

Genetic pathways to curable and incurable forms of pancreatic cancer identified

...are large enough to be detected early by MRI or CT scan and also to cause symptoms. The cells in this cancer also react differently to a key signaling protein, TGFb, which can induce cancer cells to change shape and become more mobile and invasive. It turns out that the cystic pancreatic cancer cells are ...

Research on grey mould offers possible breakthrough in tomato cultivation

...ith this in mind, Finkers next made a step-by-step scan of the entire genome of the wild tomato to identify locations that have an effect on resistance. Ten areas were found that accommodated resistance factors against grey mould. DNA-markers were then developed for each area to be able to track the prese...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...ousses and his colleagues performed a genome-scale scan of two cancer cell lines using high-throughput RNAi, "interfering" RNA strands that bind to and knock out one gene individually, across the genome. It is a systematic and highly efficient technique that uses high-speed mechanization to quickly evalua...

Computer scientists join in search for ivory-billed woodpecker

...e Observatory for Natural Environments (ACONE), to scan the skies near Brinkley, Ark., for birds. "If the system can catch any kind of bird, that's a success for us," Song said. "But if it catches an ivory-bill, that's a bonus." With a grant from the National Science Foundation, Song and Goldberg pr...

Cracking open the black box of autoimmune disease

... a DNA microarray technology developed by Young to scan the entire genome of T cells and locate the genes controlled by Foxp3. There were roughly 30 genes found to be directly controlled by Foxp3 and one, called Ptpn22, showed a particularly strong affinity. "This relation was striking because Ptpn22 ...

Nanoparticles can track cells deep within living organisms

...settings. "Kathy and colleagues showed that we can scan for these cells at the same MRI field strength we are using in medical imaging," Wickline says. "Although we reported the first use of perfluorocarbon molecular imaging for detection of certain pathologies a few years ago, no one would have predicted...

Faster, low cost sequencing technologies needed to drive era of personalized medicine

... like a caffeinated speed reader, can then rapidly scan the surface of the chip to see where DNA from the sample has hybridized to the probes. Wherever sample DNA binds to the probes, the sequence is registered. "Traditional approaches to sequencing by hybridization are limited by the number of probes...

Preliminary study finds holographic imaging system promising for cancer treatment planning

... field of view. Using high-speed electronics, a CT scan is projected onto a screen spinning inside a 24-inch transparent dome. The screen, spinning at over 900 rotations per minute, forms a detailed, holographic image that can be viewed and manipulated from any vantage point around the 360-degree dome, b...

NHGRI aims to make DNA sequencing faster, more cost effective

...r/template. A fluorescence scanner will be used to scan and identify hundreds of thousands of molecules at once. Then the cycle will be repeated. This phased award will increase if specific milestones are met in the initial experiments. J. Michael Ramsey, Ph.D., University of North Carolina, Chapel H...

Fast test for low blood flow in dogs detects early heart trouble

...After being injected, each of the dogs had a 64-CT scan of its heart and then underwent the standard test ... of heart disease and other ailments. The 64-CT scan has only been available in North America since February 2005. Each machine costs between $1.5 milli...

Stanford discovery may help predict when toxoplasma can be deadly

...uch an extra punch. By conducting a comprehensive scan of gene sequences of Toxoplasma strains, postdoctoral scholars Jeroen Saeij, PhD, and Jon Boyle, PhD, first authors of the paper in the Dec. 15 Science, searched for the gene or genes responsible for markedly increased virulence. To do such a s...

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