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Tag: "scaffolds" at biology news

NJIT Presidential Award winner takes stem cell research another step

...first stem-cell breakthrough focused on developing scaffolds that aid stem cells. She performed animal studies on rats with bone defects; she also did cell-culture studies. Both showed that the biomaterials stimulated stem cells, producing new bone tissue and fully repairing the rats' bones. Arinzeh's second ...

Nano-bumps could help repair clogged blood vessels

...engineering at Purdue. The stents are small metal scaffolds that are inserted inside arteries to prop them open during or after surgery to remove dangerous plaque deposits from the vessels. The stents, which are made of titanium and other metals, enable the arteries to grow new tissue after vessel-clogging pl...

Purdue researchers use enzyme to clip 'DNA wires'

...ly attracted to the DNA strands, which act as tiny scaffolds for creating wires. Other researchers have "metalized" DNA by coating it with copper, gold and platinum, but no other researchers have coated DNA and then cut the strands into smaller pieces using a "restriction enzyme," a class of enzyme that cause...

Scientists discover stem cell origin of neck and shoulders

...re attached. These groups of stem cells are making scaffolds of connections early during embryonic development which are later embellished and filled by other cells: just like the scaffold of a house which is later filled in by bricks, mortar and windows. If cells are from the same stem cell origin they 'stick...

New research could help us deliver genes for new bone formation

...eff at the University of Nottingham are developing scaffolds to act as a coating around the nanoscopic gene delivery systems. The scaffold controls the release of the gene delivery systems to generate the prolonged formation and development of bone tissue. The research teams are using the scaffold technology ...

Nanotubes inspire new technique for healing broken bones

...ssist the natural healing process. Artificial bone scaffolds have been made from a wide variety of materials, such as polymers or peptide fibers, but they have a number of drawbacks, including low strength and the potential for rejection in the body. "Compared with these scaffolds, the high mechanical strengt...

Bare metal stents deliver gene therapy to heart vessels with less inflammation in animal studies

Improved materials may allow stents, tiny metal scaffolds inserted into blood vessels, to better deliver beneficial genes to patients with heart disease, by reducing the risk of inflammation that often negates initial benefits. The new technique, using a compound that binds in an extremely thin layer to bar...

Bioengineers create stable networks of blood vessels

...on and through. Second, they seeded the hydrogel scaffolds with endothelial cells that make up blood vessel structure along with nerve progenitor cells from the brain. Because there is often an association of nerve connections with vascular networks, they tested to see if a combination of the blood vessel-fo...

Rice bioengineers pioneer techniques for knee repair

... honeycombed plastic templates or hydrogels called scaffolds that are used to guide colonies of donor cells. Do...iety, helped pioneer the development of coin-sized scaffolds in the early 1990s that are now the state-of-the-art clinical option for repairing small defects in ...

Virginia Tech scientists develop process for creating biocompatible fibers

...here biocompatible materials are required, such as scaffolds for tissue growth and drug delivery. The research will be presented in the Jan. 20 issue of Science, in the article, "Phospholipid Nonwoven Electrospun Membranes," by Matthew G. McKee, a recent Ph.D. graduate in chemical engineering from Virginia Te...

NJIT engineer poised to take stem cell research a step forward

...neration by combing stem cells with bio-degradable scaffolds that mimic fibers found in human cartilage tissue. They will test different scaffolds and determine which biomaterial is the best catalyst for stem cell differentiation. Again, their hop...

Bioactive cement scaffold may improve bone grafts

...,* the new technology provides a method for making scaffolds for bone tissue. The scaffold is seeded with a patient's own cells and is formed with a cement paste made of minerals also found in natural bone. The paste is mixed with beads of a natural polymer (made from seaweed) filled with bone cells. The paste...

Manchester scientists create new bio-gel for 3D cell culture

.... Uniquely, the gel mimics the properties of cell scaffolds which naturally occur in the body and has potential applications for wound healing and tissue engineering. Cell scaffolds, known as the extra cellular matrix (ECM), are naturally produced by the body to grow new cells in order to repair damaged tiss...

Microscopic scaffolding offers a 'simple' solution to treating skin injuries

...lymers can be used. The process for making the scaffolds is based on the well-known technique of electrospinning***. However, the team has made a key advance by developing a new method of making, from the same biodegradable polymers, aligned-fibre 'mats' of potential use in promoting nerve or tendon growth...

Bioengineered tissue implants regenerate damaged knee cartilage

...ture for 14 days, the researchers seeded them onto scaffolds made of esterified hyaluronic acid, grew them for another 14 days on the scaffolds, and then implanted them into the injured knees of the study patients. Cartilage regeneration was seen in ten of 23 patients, including in some patients with pre-exi...

Finding the right mix: A biomaterial blend library

... "scaffold libraries" --collections of biomaterial scaffolds made from controlled polymer blend compositions. The library currently contains scaffolds made from blends of poly(DTE carbonate) and poly(DTO carbonate). Ultimately, Becker says, the goal i...

MIT creates 3-D scaffold for growing stem cells

...se conditions. "Synthetic biopolymer microfiber scaffolds have been studied for more than 30 years to mimic ...atural destinations. "What makes these designer scaffolds particularly interesting is that cells survive longer and differentiate better without additional so...

Engineering the heart piece by piece

... U-M team and others have also shown how polymeric scaffolds can be used to engineer heart muscle of any shape or size to match the area of the damaged heart muscle ?raising the possibility of engineering customized patches to meet the specific requirements of patients. All of these approaches are described in...

Tissue engineering for craniofacial reconstruction

...ating can be used to generate rigid, biodegradable scaffolds with interconnected pores. These scaffolds are of particular interest in craniofacial tissue engineering, due to the rigidity of the resulting ...

Scientists re-grow dental enamel from cultured cells

...iddle of the tooth (dental mesenchymal cells). The scaffolds were then transferred into the abdominal cavities ...ere conditions were favorable for the cells in the scaffolds to interact and develop. When removed after 4 weeks, the remnants of the scaffolds were found to con...

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