Genomics researchers discover protein deficit that causes drug toxicity
...seases and organ transplants. The Mayo researchers say their finding advances the field of pharmacogenomics, which tailors medicine to a patient's personal genetic makeup. In the current issue of the Proceedings of the National Academy of Sciences, (http://www.pnas.org/cgi/content/abstract/102/26/9394) ...UCSD discovery may provide novel method to generate medically useful proteins
...100 trillion different antibodies, the researchers say replicating it in a test tube would be very challenging because the loops would have the tendency to fold incorrectly. "Because of its stability, the phage protein makes a better model to create protein diversity in a test tube," explained Jason M...Disappearing arctic lakes linked to climate change
...ther lakes actually increased in size. Researchers say as the climate warms, additional meltwater accumulated in the lakes located in the colder regions of thicker permafrost increase their size; however, if climate warming continues, even those lakes would eventually be susceptible to loss. "We expect ...Cells direct membrane traffic by channel width
... you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign. The roadway is in aquaporins, a class of proteins that form trans-membrane channels in cell walls in all forms of life. They allow for water movement between the cell and its environment....Aquatic plants may hold key to advancing plant disease management
... applications for managing land-based agriculture, say plant pathologists with The American Phytopathological Society (APS). According to David Schmale III, Cornell University, Ithaca, NY, many aquatic plants possess unique mechanisms of resistance to microbial attack. "Through further study, plant path...Scavenger cells could be key to treating HIV-related dementia
...es. That's one of the reasons why the researchers say developing drugs that target macrophages as well as T cells is important. These drugs could provide better treatments for dementia and potentially lead to a way to "eradicate HIV-1 infection," the study states. "You can't cure (HIV) with antiretrovi...Quick identification needed to save Florida's citrus industry from devastating disease
...ce the amount of crop loss caused by this disease, say plant pathologists with The American Phytopathological Society (APS). Citrus greening is a bacterial disease that affects the phloem system of citrus plants causing the infected trees to yellow, decline, and possibly die within a few years. The bacte...Agricultural antibiotic use contributes to 'super-bugs' in humans
... resistance in the pathogenic bacteria of humans," say David Smith of the Fogarty International Center, J...esistant bacteria to humans. Smith and colleagues say that the transmission of antibiotic resistant bacteria from animal to human populations is difficult...Less virulent strains of avian influenza can infect humans
...ng the spread of avian flu to humans. The authors say their findings highlight the importance of improving disease surveillance not only during outbreaks of highly pathogenic avian flu, but also when less pathogenic strains are circulating. To forestall genetic exchange between human and avian strains, ...Transplanting Animal Organs Could Soon Be A Reality
...ng the spread of avian flu to humans. The authors say their findings highlight the importance of improving disease surveillance not only during outbreaks of highly pathogenic avian flu, but also when less pathogenic strains are circulating. To forestall genetic exchange between human and avian strains, ...Fluoride poisoning in China due to clay, not coal
...ning because they burn a mixture of clay and coal, say researchers. The findings, from a study carried o...jor coal-burning province in China. Instead, they say that clay, which rural people in the province mix with coal powder, is to blame. Mixing clay with c...First Whole Genome Map of Genetic Variability in Parkinson’s Disease
...ng the spread of avian flu to humans. The authors say their findings highlight the importance of improving disease surveillance not only during outbreaks of highly pathogenic avian flu, but also when less pathogenic strains are circulating. To forestall genetic exchange between human and avian strains, ...Eating, body weight regulated by specific neurons
...ng the spread of avian flu to humans. The authors say their findings highlight the importance of improving disease surveillance not only during outbreaks of highly pathogenic avian flu, but also when less pathogenic strains are circulating. To forestall genetic exchange between human and avian strains, ...Women feel more pain than men, research shows
..., pain following treatment, but it is too early to say exactly how gender-specific interventions can be tailored to address these potentially important differences," said Dr Keogh. "However, evidence is certainly converging to suggest that accounting for greater differences may increase the overall effe......ng the spread of avian flu to humans. The authors say their findings highlight the importance of improving disease surveillance not only during outbreaks of highly pathogenic avian flu, but also when less pathogenic strains are circulating. To forestall genetic exchange between human and avian strains, ...Discarded placentas deliver researchers promising cells similar to embryonic stem cells
...inical setting," Dr. Strom added. The researchers say their original motivation was, and still is, to identify cells with the same therapeutic promise as embryonic stem cells. To this end, they began looking at the viability of amnion as a cell source in late 2001, obtaining discarded placentas from ful...New technology shows our ancestors ate…everything!
...rlapping data for the two species. The researchers say this suggests that both species relied on their less preferred foods during periods of food scarcity. "If members of a species live in a seasonal environment, they can get all the soft fruit they need during the wet season," Teaford added. "But come ...U-M scientists discover identifying markers for primitive blood-forming stem cells
...t discoveries in stem cell science, U-M scientists say their work raises new questions for future research. So far they have identified three SLAM markers on hematopoietic stem cells, but they have no idea what the other eight genes in the family do. SLAM gene activity creates receptors on the surface of......this possibility remains speculative. "What we can say is that our findings provide evidence that the human brain, the most important organ that distinguishes our species, is evolutionarily plastic," he said. Finding evidence of selection in two such genes is mutually reinforcing, he pointed out. "Findin...On a wing and a prayer - Alaska researchers seek clues to bird flu
...merican flyways for migratory birds and scientists say that could provide an unusual mixing ground for the evolution of new strains of bird flu - strains that could spread to lower latitudes and possibly jump to other species, including humans. University of Alaska (UAF) scientists and state and federal...