Gene silencing technique offers new strategy for treating, curing disease
... drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center. "Virtually every disease starts at the level of malfunctioning gene expression, or viral or bacterial gene expression," said Dr. David Corey, professor of pharmacology and biochemistry. "This is an appr...Scientists discover odd-ball rodent
...gallery of other unusual species. "Skeptics might say that if we are still discovering such amazing new animals, why are people worried about wildlife loss; but of course it is an indication of how little we know, and a window onto what we could be losing without ever knowing," said Dr. Timmins. ...Does vitamin C help prevent or treat the common cold? Maybe not, after all.
... compared with those taking a placebo. The authors say that the clinical significance of this minor reduc...th people who took a placebo pill. (3) The authors say that the results in this single trial are "tantalising and deserve further assessment." Douglas and...Cancer drug slows poxvirus in mice
...f the National Institutes of Health. The findings, say the investigators, suggest that Gleevec or similar drugs might be useful in preventing adverse side effects of smallpox vaccine. The classic smallpox vaccine is made from live, weakened vaccinia virus and is not recommended for people with compromise...Scientists discover global pattern of big fish diversity in open oceans
... swordfish, and other ocean predators. Scientists say these hotspots - off the east coasts of the US, Au.... There is real cause for alarm here." Scientists say losing the variety of fish does not bode well for the future health of open oceans. A robust portfol...Program finds lost genes in nematode genome
...uration by human experts. Brent and his colleagues say that the accuracy of WormBase can be improved with the use of TWINSCAN predictions. And Brent predicts that the age of the human genome annotator is passing ?the future belongs to computer-driven annotation. Crossing the tipping point "We've crosse...Diabetic nerve therapy shows 'striking' results
...uld bring relief to millions of diabetic patients, say experts. The treatment might also reduce the number of amputations of toes and feet if early effects on nerve protection and regeneration are borne out long-term. Nerve disease in diabetes is the major cause of non-traumatic lower limb amputations i...Specialized immune-system B cells play double-barreled role
...and regulate their function. "We certainly cannot say whether these particular findings about the role of these B-1 cell subtypes will directly impact on vaccine development," said Tedder. "However, understanding such key characteristics of the immune regulatory process will be critical to learning to s...One hit of crystal meth causes birth defects
...e long-term neurodevelopmental problems in babies, say University of Toronto researchers. In research published in the August issue of Free Radical Biology and Medicine, U of T pharmacy and pharmacology professor Peter Wells and his colleagues determined that exposing pregnant mice only once to methamph...Researchers find first evidence of venom system in extinct mammal
...o answering a long unsolved evolutionary question, say researchers from the University of Alberta. Back in 1991, Dr. Richard Fox and his research team found a 60 million year-old incomplete skull fossil that they now believe is the first evidence of an extinct mammal with a venom delivery apparatus. The...Poaching, logging, and outbreaks of Ebola threaten central African gorillas and chimpanzees
...las and chimpanzees in Central Africa, and experts say $30 million is needed for special programs to save some of mankind's closest relatives from disappearing. An action plan drafted by more than 70 primatologists and other experts who met in Brazzaville, Republic of Congo, in May designates 12 areas f...When it comes to cell entry, being average has its advantages
... do want molecules to get in ?those in medication, say ?knowing an optimal particle size for entry is also helpful. "With nanotubes, we may be able to manufacture ones of a certain size to minimize chances that they'll enter and perhaps harm cells." The type of cell entry the team studied is called rec...Study shows humans have ability to track odors, much like bloodhounds
...alization, that is, keep their head motionless and say where the spatial source of an odor is," said study coauthor Noam Sobel, associate professor of psychology at UC Berkeley and a member of the campus's Helen Wills Neuroscience Institute. "It seems that we have this ability and that, with practice, yo...Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
...centrated in the downwelling zone. The scientists say the ecological implications of the zooplankton's depth-keeping behavior carry far-reaching consequences for predatory fishes, whales and humans. Predators can dependably locate zooplankton aggregations by tracking well-defined cues, for example, sha...Caloric restriction won't dramatically extend life span in humans: UCLA research
...onary biologist John Phelan. "I once heard someone say caloric restriction may not make you live forever, but it sure would seem like it. Try to maintain a healthy body weight, but don't deprive yourself of all pleasure. Moderation appears to be a more sensible solution. "With mice, if you restrict the...Understanding biases in epidemic models important when making public health predictions
...ns that may systematically bias their predictions, say researchers at the University of Georgia. In a paper published today in the online open-access journal PLoS (Public Library of Science) Medicine, Helen Wearing and Pejman Rohani of the Institute of Ecology at the University of Georgia and Matt Keeli...International Team Determines Geographic Origin of Leprosy
...y spread to West Africa directly from East Africa, say the researchers. The international team of investigators, who identified rare genetic variations among strains of the bacterium that causes leprosy, included Patrick J. Brennan, Ph.D., of Colorado State University in Fort Collins. Dr. Brennan is a g...Inhaling large amounts of salt can cause hypertension
...ns that may systematically bias their predictions, say researchers at the University of Georgia. In a paper published today in the online open-access journal PLoS (Public Library of Science) Medicine, Helen Wearing and Pejman Rohani of the Institute of Ecology at the University of Georgia and Matt Keeli...Field of beams - Novel system uses polarized light pulses to reveal crop health
...ns that may systematically bias their predictions, say researchers at the University of Georgia. In a paper published today in the online open-access journal PLoS (Public Library of Science) Medicine, Helen Wearing and Pejman Rohani of the Institute of Ecology at the University of Georgia and Matt Keeli......or the inability to taste sweets?" Brand adds, "I say jokingly, no wonder cats are cranky--not only do they have to hunt for their food, but they also can't enjoy a sweet dessert!" Citation: Li X, Li W, Wang H, Cao J, Maehashi K, et al. (2005) Pseudogenization of a sweet-receptor gene accounts for cats...