New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal
...get antibiotics to market faster and more cheaply, say University of Florida researchers. In recent year...alone saves a lot of money.?/p> UF researchers say they will continue to apply the screening approach to other drugs in various situations and also wil...Key mechanism in genetic inheritance during cell division identified
...otubule binding protein complex. While the authors say that ring formation is a complicated way to construct a microtubule binding structure, a microtubule binding ring might be uniquely suited to fulfill the functions of the Dam1 complex. In comparison with the purified Dam1, the Dam1 mutants produced p......o injured hearts in study mice. The authors can't say why skeletal muscle would harbor cardiac stem cells, but for now, the Spoc cells provide a valuable tool for studying heart cell differentiation. And with time, they might prove an important resource for developing cell-based therapies for heart dise...Promising new West Nile therapy cures disease in mice
... The researchers tested their antibody in mice and say its success warrants further development and testing in people with West Nile disease. "West Nile virus has emerged in the United States as a regular seasonal threat, particularly for people over 50. We currently do not have a proven therapy for peo...Youth With HIV Take More Risks After New Meds Introduced
... HIV-positive youth studied between 1994 and 1996, say Marguerita Lightfoot, Ph.D. and colleagues at the UCLA AIDS Institute at the David Geffen School of Medicine. Highly active antiretroviral therapies, or HAART, were introduced in 1996. The new drugs have successfully lowered virus levels and prolong...Scientists journey to southern Africa to unravel the secret world of elephant communication
...only played back one type of call, we can't really say whether they were interpreting it correctly. Maybe they thought it was a vehicle or something strange instead of a predator warning." (To hear actual elephant vocalizations, visit the website http://www.elephantvoices.org/index.php?topic=resources.)...Double triumph in stem cell quest
...ernative sources of ESCs. But he and other experts say Verlinsky must do a lot more work to prove his claim. While ESCs show great promise for treating many diseases, such as heart disease, diabetes and Parkinson's, non-matching ESCs would be rejected by patients' immune systems unless they take immunos...What's really making you sick? Plant pathologists offer the science behind Sick Building Syndrome
...Sick Building Syndrome may improve its management, say plant pathologists with The American Phytopathological Society (APS). Sick Building Syndrome (SBS) refers to a situation in which building occupants experience health problems while inside a particular building. Human health issues typically associa...Grizzlies set to invade high Arctic?
...re not wildlife biology experts. Nonetheless, they say the discovery of a grizzly bear on Melville Island...ses when we go up there, and people would normally say you don't have to worry about grizzlies because it's really just polar bear country," he says. "But ...Scientists discover that three overlapping signals in embryo help get the backbone right
...s are from mice or amphibians, but the researchers say that the same is almost certain to be the case in humans. "One of the things that's been nicely shown is that the organizer itself, while it was originally identified in newts, is conserved through all vertebrate evolution," Khokha said. "If you cut...Genetic therapy reverses nervous system damage in animal model of inherited human disease
...is approach can be successfully applied to humans, say the researchers, it might one day treat an entire class of diseases called lysosomal storage disorders which cause severe, sometimes fatal, disabilities in about one in 5,000 births. The members of the research team from the University of Pennsylvani...Advancements In Genomics Foster Deep Sea Discoveries
...quare inch of “skull-crushing?pressure. Scientists say precious information lies in discovering how organisms have adapted and evolved to such conditions. Bartlett and his colleagues probed the genetic makeup of Photobacterium profundum, a bacterium that copes with pressures of 4,000 pounds per square i...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
...s to cancer formation were missing in the animals, say researchers from the Albert Einstein Cancer Center...g of the American Association for Cancer Research, say that while the results do not yet have relevance for preventing human colon cancer, they do illustra...Doctors closer to using gene analysis to help trauma patients
...thy people. Among the trauma patients, researchers say “analytical noise??differences attributable to the testing method ?was not significant, suggesting that profiling gene reactions may provide meaningful information to doctors. The next step is for scientists to continue the experimental procedures i...To sea or not to sea: When it comes to salmon sex, size sometimes doesn't matter
...ying is just one of the traits that cause Quinn to say that salmon have chances to recover from years of declines "if we would only take our collective foot off their neck." "A great deal of habitat from southern British Columbia to California is no longer accessible to salmon or has been altered to the...Putting ecology back into river restoration
...and stream restoration." Palmer and her colleagues say that the success of river restoration should be judged according to five criteria: a guiding image; improving ecosystems; increasing resilience; doing no lasting harm; and completing an ecological assessment. The first step should be articulating a ...Taking the piste out of Alpine vegetation
... times more bare ground than ungraded pistes. And, say the researchers, this damage is long lasting. They found pistes that had been machine graded as long as 30 years ago and re-sown with plant seed had still not recovered. "Machine grading constitutes the most drastic vegetation disturbance on ski pist...Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol
...ug Taxol are effectively killing tumor cells. They say that with further refinement, the test may make it possible to accurately assess whether patients are responding to these agents, as well as potentially others, within days of beginning therapy. In two different studies being presented at the annua...Secret of smallpox's success may lead to bioterror cure
...in, the more likely it is for the immune system to say 'Hey, wait a minute! There is something going on here! I need to start fighting a virus infection!' and so it fights the mutant virus and a normal pathogenic virus as well." The gene that Jacobs has isolated and eliminated from the mutants is a spec......in Reproduction and Women's Health, and colleagues say that these investigations point the way to a new type of contraceptive for both men and women. They report their findings in this week's online edition of the Proceedings of the National Academy of Sciences. "Not many proteins are expressed in both ...