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New SARS Protein Linked To Important Cell Doorway

As public health officials in China brace for a potential resurgence in SARS (Sudden Acute Respiratory Syndrome) in connection with Chinese New Year on February 9, researchers at Washington University in St. Louis have published insights into a new protein that could be an important contributor to the SARS virus' ability to cause disease and death. .. When the SARS virus first jumped from its sti...

New studies suggest airborne SARS transmission is possible

Two new studies present evidence that the virus causing severe acute respiratory syndrome (SARS) may spread through the air, not just through direct contact with contaminated water droplets as previous research had shown. . SARS coronavirus was detected in the air in a patient's room during the 2003 outbreak in Toronto, according to a new study published in The Journal of Infectious Diseases. Ano...

UIC developing drug for SARS

A prototype drug created by researchers at the University of Illinois at Chicago shows promise in slowing replication of the virus responsible for severe acute respiratory syndrome, or SARS. .. . On the basis of their success, the researchers have received an $8 million grant from the National Institute of Allergy and Infectious Diseases to develop protease inhibitors that would block key enzymes...

New study shows SARS can infect brain tissue

Severe acute respiratory syndrome (SARS), by its very name, indicates a disease of the respiratory tract. But SARS can also infiltrate brain tissue, causing significant central nervous system problems, according to an article in the Oct. 15 issue of Clinical Infectious Diseases, now available online. . SARS, a potentially fatal illness caused by a coronavirus, was first reported in Asia in Februa...

Learning how SARS spikes its quarry

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection. The structure, which shows how the spike protein grasps its receptor, may help scientists learn new details about how the virus infects cells. The information could also be helpful in identifying potential we...

Enzyme inhibitors block replication of SARS virus

The study was conducted by researchers from Scripps Research; the Genomics Research Center, Academia Sinica, Taiwan; and the National Taiwan University. It is being published today in the journal Chemistry and Biology (Vol. 13, No. 3). . .. "We have been working on the problem of SARS since the epidemic started in 2003," Wo...

Researchers find 'secret weapon' used by SARS virus

In 2003, the highly contagious and often-deadly mystery disease now called SARS emerged explosively out of Southern China. It eventually killed an estimated 916 people in Asia, Europe, and North and South America--nearly one in ten of those it infected. . .. Now, in a disco...

SARS: No evidence that any of the treatments worked

The SARS virus set alarm bells ringing across the world when it first appeared in 2002, but now a review of the effectiveness of the treatments used against it has found no evidence that any of them worked. The review was commissioned by the World Health Organization and has been published in PLoS Medicine. . Severe acute respiratory syndrome (SARS) is caused by a virus; the main symptoms are pne...

Household transmission of SARS: Lessons learned

In the 2003 outbreak of severe acute respiratory syndrome (SARS) in Toronto, Ontario, about 20% of cases resulted from household transmission (spread of the infection within a household). . .. SARS presented a u...

Restricting hospital-based services during SARS outbreak had modest impact

Restrictions on the non-urgent use of hospital-based services that were imposed when a provincial health emergency was declared during the 2003 SARS (Severe Acute Respiratory Syndrome) outbreak in Toronto, Ontario, resulted in only modest reductions in overall admissions. In this study, Dr. Michael J. Schull and colleagues determined that restrictions on the non-urgent use of hospital-based serv...
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