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Tag: "sarcoma" at biology news

Synthetic peptide targets latent papilloma virus infections

...ukemia called Burkitt's leukemia, and the Kaposi's sarcoma virus, which can develop to cancer in those with AIDS. ...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

Kaposi’s sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi’s sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival tim...

New way of tracking muscle damage from radiation

...before and after radiation therapy for soft tissue sarcoma and Ewing sarcoma are related not only to the amount of radiation the child received, but also to the child's age and ...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...ers new potential strategies for treating Kaposi's sarcoma and other cancers associated with viruses. KSHV i... patients are at high risk for developing Kaposi's sarcoma and another cancer called primary effusion lymphoma. The study describes how a KSHV-encoded prot...

Scientists tie several cancers to common 'oncogene engine'

... a dangerous type of soft-tissue tumor ?clear cell sarcoma ?that develops near muscles and tendons in teenage...possibility of MITF involvement because clear cell sarcoma tumors are sometimes pigmented ?a process requiring the MITF transcription factor. In this form of s...

Landmark discovery of a Kaposi's sarcoma-associated herpesvirus receptor

...surface molecule involved in infection by Kaposi's sarcoma herpesvirus (KSHV), the virus that causes Kaposi's sarcoma and certain forms of lymphoma. Kaposi's sarcoma is a major cancer associated with HIV/AIDS, and it t...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

...al viruses fusing with a host cell membrane. Avian sarcoma and leukosis virus (ASLV), a virus that is in the same class as HIV, was used in the study. The researchers discovered that once the virus fuses with the host cell membrane the hole, or pore, through which the virus unloads its deadly genetic cargo ...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

...into tumor cells has been shown to inhibit Ewing's sarcoma in an animal model of the disease. In this classi...gene called EWS-FLI1 that's active only in Ewing's sarcoma tumors. Once inside these cells, the genetic machinery of the tumor cells are effectively silenced ...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

...py (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study... in the study had a highly elevated risk of Kaposi sarcoma and non-Hodgkin lymphoma. They also had an increased risk of anal cancer, Hodgkin lymphoma, cervical...

How an AIDS-Related Cancer Unleashes Inflammation

...have drastically reduced the incidence of Kaposi's sarcoma in developed countries, it remains a health threat... researchers have discovered one way that Kaposi's sarcoma ?a cancer-like viral disease traditionally associated with AIDS ?triggers severe inflammation. Don ...

Association of herpesvirus with lung disorder questioned

... herpesvirus 8 (HHV-8), also known as the Kaposi's sarcoma virus, in the lungs of 22 patients with primary or...r a control group, the scientists studied Kaposi's sarcoma tissue samples obtained from unrelated patients. Like the authors of the earlier study, Katano and ...

Viral DNA sequence a possible trigger for breast cancer

...ng viruses such as Epstein Barr virus and Kaposi's sarcoma virus, but what role this sequence plays in cancer development has remained unexplored. Katz and colleagues now show that this sequence is contained in the Env protein of MMTV and show that expression of Env in mouse breast cells transforms them. Th...

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