A genetic 'gang of 4' drives spread of breast cancer
...cells in the primary tumor," said Massagué. "These same genes, we believed, might also be used for some re...gué. "We concluded that metastatic cells use these same genes to loosen up cells in capillaries, so that the cells can penetrate the lung tissue to grow the...Newborn brains grow vision and movement regions first
... thought experiences very little growth during the same period, University of North Carolina at Chapel Hill researchers have found. The researchers discovered that the back regions of the brain, which control vision and sensory integration, grew significantly faster than the prefrontal region, which cont...Renegade RNA -- Clues to cancer and normal growth
...aterial is kept. The researchers then stuck the same six-block end onto another type of small RNA, a small-interfering RNA or siRNA that turns off genes. This also forced the siRNA into the nucleus. According to Mendell, these results demonstrate for the first time that despite their tiny size, micr...New recommendations against a major opportunistic infection -- cryptococcosis
...Institut Pasteur, and Olivier Lortholary, from the same Pasteur unit and the Necker-Pasteur Infectiology Centre, in collaboration with the French Cryptococcosis Study Group, which is composed of mycologists and clinicians in 77 centres throughout the territory. Aiming to analyse the factors influencing...NASA predicts nongreen plants on other planets
... use extra green light. But not all stars have the same distribution of light colors as our Sun. Study sci...n extrasolar planets will not necessarily look the same as on Earth. "It makes one appreciate how life on Earth is so intimately adapted to the special q...Cold sore virus might play role in Alzheimer's disease
...d that the virus infiltrates brain cells about the same no matter which gene is involved. But they found that the subsequent activity level of the virus generally mirrored the disease-causing potential of the gene. They found that in animals with the ApoE-4 gene, the virus is less likely to be in the quie...Gene elevating breast cancer risk also causes prostate cancer
...rations in 113 Finnish breast cancer families. The same constitutional mutation in PALB2 was observed in three families. It was later showed that the relevant mutant protein is deficient in its ability to support the kinds of DNA damage responses in which PALB2 normally participates. The mutation was furt...Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
...t that idea." In another study appearing in the same issue of Science, Mary Schweitzer, of North Carolina State University, and colleagues found that extracts of T. rex bone reacted with antibodies to chicken collagen, further suggesting the presence of birdlike protein in the dinosaur bones. The me...Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps
...t relied on the rhesus sequence also appear in the same issue. The rhesus genome is the second non-human primate, after the chimp, to have its genome sequenced and is the first of Old World monkeys to have its DNA deciphered. "The sequencing of the rhesus macaque genome, combined with the avai...Genetic pathways to curable and incurable forms of pancreatic cancer identified
...c cancer behaves differently, despite carrying the same basic genetic mutations as the more common and dea...to ductal pancreatic cancer can look very much the same under the microscope, involve the same constellation of genetic events, and culminate in invasive an...New technologies coming too fast for Indian farmers
...ne says. "Many different brands are actually the same seed," he says. "Farmers can't recognize what they are getting. As a result, the farmers can't properly evaluate seeds. Instead, they ask their neighbors. Copying your neighbor isn't necessarily a bad thing; but in this case, everyone is copying ever...Cancer-killing invention also harvests stem cells
...ct, it stays active for many weeks or months. The same TRAIL molecules can kill enormous numbers of cancer cells. A possible way to use the cancer-killing invention is to implant the device in the body before primary tumor surgery or chemotherapy. When doctors remove a primary tumor, the procedure i...Bacteria control how infectious they become, study finds
...se-causing bacteria infect their host while at the same time protecting the bacteria from the host's immune defenses. “E. coli seems to prevent RfaH from acting unless the microorganism absolutely needs it,?Artsimovitch said. That's because bacteria like E. coli are caught in a delicate balancing act. ...Technology reveals 'lock and key' proteins behind diseases
...is safe to assume they participate or regulate the same cellular process," explains Stagljar. "Identifying new interactors for ABC transporters may reveal unanticipated aspects of how these transporters function and help researchers gain clues for fighting disease and drug resistance." Using iMYTH, t...New mechanism for nutrient uptake discovered
...for this activity, the scientists believe that the same feature could occur across species. The discovery, published in the February 11th on-line edition of Nature, has widespread potential—from understanding human diseases, such as kidney function, to engineering better crops. "Every cell in every organ...Trusting your instincts leads you to the right answer
...ical symbols, including one rotated version of the same symbol, actually performed better when they were g...onscious brain recognises a rotated version of the same object as different from the original, whereas the conscious brain sees the two objects as identical...Penn study on olfactory nerve cells shows why we smell better when we sniff
...emical and mechanical stimuli both resulted in the same messenger molecule, cAMP, which acts like a gatekeeper of reactions in the olfactory neurons. Although this study was conducted on a mouse model, the researchers tested two different parts of the nose, one that humans have and one that humans do...Antibody therapy prevents type 1 diabetes in mice
... of regulatory T-cells. If we can demonstrate this same genetic predisposition and therapeutic effect in human type 1 diabetes patients, then this may prove to be a significant step toward preventing this disease before it can take hold," he explained. ...Saving endangered whales at no cost
...r than in the Canadian Fishing Area to harvest the same lobster catch. On the basis of these findings and estimations of seasonal whale presence determined by patterns of whale sightings, the authors estimate that, in terms of impact on right whales, each lobster caught in Canada has less than 1% of the i......ch would allow us to use adult stem cells from the same patient rather than those harvested from an unrela...t survive until adulthood. By using cells from the same mouse and performing the experiments on the two successive days, the Rockefeller scientists could di...