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Tag: "sabotage" at biology news

Newly discovered pathway might help in design of cancer drugs

...ohns Hopkins chemists have discovered a new way to sabotage DNA's ability to reproduce, a finding that could eventually lead to the development of new anti-cancer drugs and therapies. The method could enable future doctors to target treatment more precisely, rather than directing chemotherapeutic medication ...

To control germs, scientists deploy tiny agents provocateurs

... creating artificial chemicals that infiltrate and sabotage bacterial "mobs." Reporting the work here today (March 13) at the 229th national meeting of the American Chemical Society, University of Wisconsin-Madison chemistry professor Helen Blackwell described the ongoing construction of a new class of molec...

Study provides insight into cellular defenses against genetic mutation

...mRNAs create shortened, disabled proteins that can sabotage natural processes by competing for spots usually held by their full-length counterparts, or by simply not working. In recent years, researchers at the University of Rochester Medical Center have revealed the existence of a natural surveillance syst...

Researchers find 'secret weapon' used by SARS virus

... "secret weapon" that the SARS coronavirus uses to sabotage the immune defenses of infected cells. Experiments conducted by the UTMB scientists show that a SARS coronavirus protein called "nsp1" causes the breakdown of biochemical messages that normally prompt the production of a protein critical to defending...

Key to lung cancer chemo resistance revealed

...top this cleansing process. But lung cancer cells sabotage the expression of these same genes to block assault from chemotherapy drugs. "What we're seeing is that lung cancer cells recruit and distort NRF2 and KEAP1 expression to help tumor cells evade the toxic effects of chemotherapy," says Shyam Biswal...

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