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Tag: "run" at biology news

Twin studies reveal genetic components leading to cardiac and kidney disease

...rs before," said O’Connor. "Now we know that they run in families, not only because of a shared environment, but because they are determined in part by particular genes. "Behavioral studies with twins have been conducted for decades, but in the post-genomic era, we can now factor in genotypes and det...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...epartment of Immunology. "While we are unlikely to run large-scale trials with this particular form of the vaccine due to difficulty in its manufacturing, we have learned a tremendous amount from the subjects that benefited from the trial, which may translate well into more practical vaccine formulations...

20-year study shows significant rise in childhood obesity, especially among girls

...e children become overweight and obese adults they run a much higher risk of developing cardiovascular disease and type-2 diabetes." ...

Elucidation of the genome for diabetics with DNA chips

...subjects from the DESIR study, a prospective study run by INSERM and directed by Beverly Balkau. The key results of this first screening were then confirmed in more than 5500 French diabetic patients treated at Corbeil-Essonnes Hospital (Guillaume Charpentier) and Poitiers University Hospital (Samy Hadja...

Scientists find new genes for Crohn's disease

...re than 1 million Americans. Because IBDs tends to run in families and are more frequent in certain ethnic populations, especially Ashkenazi Jews, scientists have long suspected that they have a significant genetic component. Previous genetic studies have found strong links between Crohn's disease and...

Keeping the body in sync -- The stability of cellular clocks

... in physiology, gene expression, and behavior that run on a cycle of approximately one day, even in conditions of constant light or darkness. Peripheral organs in the body have their own cellular clocks that are reset on a daily basis by a central master clock in the brain. The operation of the cellular ...

Researchers find gene mutation that causes infertility in male mice

...mc1 mutation are born with fewer egg cells and can run out of eggs prematurely -- resulting in early menopause (or "mousapause" as the researchers humorously refer to the condition). To get their results, the researchers randomly induced mutations in the mouse genome and then looked for infertility in ...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

... explore how bacteria use these parts to build and run their key functions ?some of which have potential uses in bioenergy. The genome has revealed surprises, he says. "Microorganisms typically require two kinds of enzymes to efficiently break down cellulose," he says. "One type cuts the long carbohy...

'Marathon mice' elucidate little-known muscle type

...were full of the so-called IIX fibers were able to run farther and at higher work loads than normal mice could. The findings could ultimately lead to novel drugs designed to change the composition of muscle, the researchers said. Such treatments might have the potential to boost physical strength and en...

Need oxygen? Cells know how to spend and save

...ep the motor running smoothly even as it begins to run out of gas," says Gregg Semenza, M.D., Ph.D., a professor of pediatrics and director of the vascular biology program in the Institute for Cell Engineering at Hopkins. "This is one way that cells maintain energy production under less than ideal condit...

UCI scientists reconstruct migration of avian flu virus

...ding across a large area, the virus in essence can run multiple experiments in multiple locations, increasing the likelihood that it will mutate into a form that can be transmitted from human to human." Avian flu has been isolated almost exclusively among bird populations. The H5N1 virus has only spor...

Switching genes to overdrive improves muscular dystrophy symptoms in mice

...dditional PGC-1alpha. Both sets of rodents were run on a treadmill for one hour, then again 24 hours later. Normal mice completed the runs easily on both days, while untreated MDX rodents were exhausted halfway through each run. The MDX mice with increased PGC-1alpha activity performed almost as well ...

Warts vaccine -- 1 of many in pipeline

... and Australia have taken part in the trial so far run from the Princess Alexandra (PA) Hospital. "The new treatment has so far proven safe, and we want to know if it improves the outcome after conventional therapy, which all patients also receive," Dr Jardine said. Trial researchers aim to use a ...

Diminishing dinosaur steps saved by laser and laptop

...nts in which they lived. The on-going project - run in conjunction with Universitat Autonoma de Barcelona - is being led by palaeontologist Dr Phil Manning, who received a grant of Euro 9,000 from the Consorci Ruta Minera to fund the laser scanning. The computer modelling for the project was done b...

Master regulatory gene of epithelial stem cells identified

...mor-suppressing p53 gene. Without p63, mutant mice run out of the regenerative epithelial stem cells. Th...fect is simply running out of stem cells. When you run out of stem cells, you run out of those tissues as we have seen with the mice lacking the p63 gene."...

Lessons from the orangutans: Upright walking may have begun in the trees

...he straight legs is still unclear, but when humans run on springy surfaces, we also keep our weight-bearing legs relatively straight, so this may have an energy-related advantage. "Our results suggest that bipedalism is used to navigate the smallest branches where the tastiest fruits are, and also to ...

For many insects, winter survival is in the genes

...d to high heat. Humans make these proteins when we run a high fever. "But insects make these very same stress proteins during times of low temperature as well as during exposure to high levels of toxic chemicals, dehydration and even desiccation," Denlinger said. He and his colleagues first figured...

Ants show us how to make super-highways

...f forager traffic, along which prey-laden foragers run back to run back to the nest. This trail can be extremely uneven and full of ‘pot holes’ as it passes over leave...

Male circumcision overstated as prevention tool against AIDS

...ivist claiming that a rabid dog must be allowed to run free in a neighborhood regardless of how many men women and children he infected and killed. It is not surprising that computer models rarely show the virus reaching epidemic proportions; it is very hard to transmit this illness heterosexually. On...

Penn researchers link cell's protein recycling systems

...osomal and the proteasomal systems are trains that run on different tracks, with similar purposes, but no point of intersection,” explains senior author J. Paul Taylor, MD, PhD, Assistant Professor of Neurology. “The new finding directly challenges this thinking by showing that one system can be induced ...

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