roles 2 8

Tag: "roles" at biology news

MSKCC researchers uncover structure of key protein complex in cells

...of SUMO and ubiquitin. "Identifying the additional roles of sumoylation may well provide us with new targets to inhibit the protein and therapeutic agents for cancer and other conditions in which SUMO is involved." The study also casts light on a poorly understood aspect of cellular communication. The MSK...

miRNAs and musculature

...s an essential tool for identifying the biological roles of miRNAs. ...

NYU biologists map out early stages of embryo formation

...f the animal. The results further suggest specific roles for new genes that had not been studied before, and functional tests of a subset of these supported the predictions. Describing how embryos function at the molecular level may help understand how human embryos develop, and may also provide new insig...

Virus uses tiny RNA to evade the immune system

...dence that the little molecules can play important roles not only in normal human cells but in infected cells as well. "A popular notion is that the whole system of generating small RNAs was designed to be a defense by cells against viruses. Our study shows that a virus can also adapt it to evade the immu...

Trio of plant genes prevent 'too many mouths'

...e touching each other. These genes appear to have roles at two points in the production of stomata. First, they inhibit undifferentiated cells ?those unspecialized cells that have yet to turn into specific cell types ?from making too many stomata and then they repress the development of two guard cells th...

Single gene is genetic switch for fly sexual behavior

...these cases, "we have been able to reverse the sex roles during Drosophila courtship," Dickson and Demir say. Dickson and Demir created male-spliced versions of fruitless in female flies and female-spliced versions in male flies. Males with the female version of fruitless "barely court at all" when paired...

Computer modeling reveals hidden conversations within cells

... mystery: how the same proteins can play different roles in a wide range of cellular processes, including those leading to immune responses and cancer. Prior to the UCSD team's findings, which are published in the September 16 issue of the journal Science, many scientists expressed doubts that a computat...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...s' experiments revealed that PI(3)K plays multiple roles as an enzyme that affect heart responses. It manufactures signaling molecules called phospholipids in the cell. And it activates other molecules, among them one called "non-muscle tropomyosin," which plays an important role in maintaining cell struct...

Muscle repair: Making a good system better, faster; implications for aging, disease

... * The plasminogen system likely has multiple roles in muscle repair. Understanding how the plasminogen system works in skeletal muscle may give some clues to improving repair of different tissues, especially heart, which is similar in many ways to skeletal muscle. ...

Once given 'no respect,' cells' tiny RNAS take driver's seat

...NA not used to make proteins actually play central roles in normal biology and in the development of cancer... protein building-instructions. The microRNAs play roles in cell division, cell specialization and cell death in worms and flies and are off-kilter in human ...

Deep sea buffet for bone-devouring worms

...acterial 'partners' are likely to play substantial roles in the cycling of nutrients into the surrounding deep-sea community." This can be put into context by considering that the Osedax worms and their symbiotic bacteria can turn-over a large amount of organic carbon (one whale carcass may weigh up to 50...

One bacteria stops another on contact

...infancy, but opens the door for exploration of the roles of contact-dependent growth inhibition in urinary tract infections and possibly other diseases," said Low. "Aoki has discovered an entirely new phenomenon," explained Low, who has studied E. coli for over 20 years. "It is fascinating that bacteria h...

Proposal would allow wild animals to roam North America

...mals near the top of the food chain play important roles in structuring ecological systems and maintaining biodiversity, according to the paper. These keystone species -- animals that contribute to diversity of life and which the rewilding researchers would like to reintroduce -- play a disproportionate ro...

Energy management in cells may hold key to cancer defense

...ss a large family of enzyme proteins that play key roles in the workings of most animal cells. He has focu...y as a classroom, Witters pointed out the integral roles played by Hurley and Dartmouth College undergraduate student Jeanne Franzone '05, a co-author of the...

Laboratory professionals in Africa receive training under AIDS Relief Plan

...e past year, 14 ASCP volunteer members have played roles assessing the situation in Africa, serving as trainers, and participating in Work Groups developing training materials. Estimates are that some 40 million people are living with HIV/AIDS in developing nations. In Zambia, for instance, some 1.2 mil...

Most common lung cancers may begin in newly discovered cells

...ironment for stem cells of the lung, including the roles of the neighboring cells that support the stem cells and specialized lung cells. Still, she says their studies are as rigorous as the generally accepted reports of stem cells found in the skin, brain, testes and gut. The lab has already teamed up wi...

Attacks of King George III's madness linked to key metabolism molecule

...r intimate knowledge of PGC-1 alpha and its varied roles in energy metabolism, the Dana-Farber researchers wondered if it might be involved in porphyria, since PGC-1 alpha is a regulator of heme manufacture in the liver. One of its actions is controlling the activity of the ALAS-1 gene that makes a protein...

Unraveling a stomach cancer puzzle

...ortantly without affecting Stat3's other important roles in the body. Add to that the evidence suggesting that Stat3 is also involved in breast, head and neck, and prostate cancers, and we have a compelling case for investigating the development of therapies that target Stat3." ...

Scientists find microRNAs regulate plant development

...development and show that microRNAs play important roles in regulating the auxin response pathway. You can read the full report News and Reviews article on this research in The Plant Cell at http://www.plantcell.org/pressreleases/IN_THIS_ISSUE.pdf. The research papers cited in this report are available a...

Scripps research scientists identify infertility molecule

...ructural elements. Some play significant signaling roles in the cell. LPA belongs to a family of phospholipids known as "lysophospholipids." These molecules play a more active role in the mammalian body, acting as signals for many different developmental events and adult physiology. Chun and his colleague...

1 2 3 4 5 6 7 8 9 10