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Tag: "rodents" at biology news

Switching genes to overdrive improves muscular dystrophy symptoms in mice

...e having no additional PGC-1alpha. Both sets of rodents were run on a treadmill for one hour, then again 2... the runs easily on both days, while untreated MDX rodents were exhausted halfway through each run. The MDX mice with increased PGC-1alpha activity performed a...

In young mice, gregariousness seems to reside in the genes

...ism. In past research, the social capacities of rodents have been studied primarily in the context of behaviors associated with sexual reproduction, territorial defense and parental care. Those studies, say Lahvis and Panksepp, do not account for the many forms of social interaction that occur prior to se...

Glucose triggers brain cell death in rats after hypoglycemic coma

...istered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical...tion. In their study, the researchers subjected rodents to a model of severe hypoglycemic coma. "The rats could remain hypoglycemic without evidence of sign...

Discovery could lead to better control of hemorrhagic fever viruses

... them to more severe infection when exposed to the rodents that carry the viruses. Choe's lab is now trying to find the cellular receptor for other viruses that cause hemorrhagic fever in humans. In 2003, Choe's lab collaborated with Farzan's lab to identify angiotensin converting enzyme2 (ACE2) as the re...

White blood cells in lung produce histamine seen in allergies

...e to mycoplasma, a common respiratory infection in rodents and humans. One population had a genetic abnormality that causes a total lack of mast cells; the other population was made up of normal, wild-type mice. Both populations of infected mice developed pneumonia. "We thought the mice without mast cells...

OHSU lab finds meth receptor that could lead to therapy

... real target of methamphetamine and amphetamine in rodents and probably humans, too." Grandy added that it's his hope that "these findings will eventually lead to the development of new pharmaceuticals that reduce dependence on and craving for methamphetamine." The study is published in the April editi...

Experimental vaccine given during pregnancy reduces stillbirths from common virus

...xperimental vaccine that reduces stillbirths among rodents born to mothers infected with cytomegalovirus (CMV...in their third trimester. Tests showed that the rodents given the experimental vaccine had acquired immunity to guinea pig CMV because they produced antibod...

Scientists discover new species of distinctive cloud-forest rodent

...tless. I. barbarabrownae belongs to a family of rodents known as "spiny rats" because most of the species in that family bristle with spines. Its discovery has necessitated a re-examination of this tropical American family, especially its closest relatives, the bush-tailed tree rats found in South America...

Does a peptide affect the heart's response to social isolation?

...disease. Prairie voles (ochrogaster) are small rodents that demonstrate features of social interactions similar to humans and therefore provide a useful animal model for investigating how the social environment influences behavior and cardiac function. Earlier studies by this research team showed that wh...

Hopkins researchers discover how brain protein might control memory

...d behaviors ranging from song learning in birds to rodents being aware of 3-D space. In people, Arc may be one culprit behind certain long-term memory-based behaviors like drug addiction, the researchers say. "We think Arc controls how brain cells learn and associate behaviors and remember them over a lo...

MIT material stops bleeding in seconds

...biodegradable liquids can stop bleeding in wounded rodents within seconds, a development that could significantly impact medicine. When the liquid, composed of protein fragments called peptides, is applied to open wounds, the peptides self-assemble into a nanoscale protective barrier gel that seals the woun...

Longer-lived rodents have lower levels of thyroid hormone

... an important role in longevity, with longer-lived rodents showing significantly lower levels of a thyroid ho...he study "Differential thyroid hormone activity in rodents with different life spans" at a poster session Oct. 9 at Comparative Physiology 2006: Integrating Di...

Human stem cells delay start of Lou Gehrig's disease in rats

..., Koliatsos hopes to take further advantage of his rodents with ALS to learn as much as possible about how human stem cells behave when transplanted. ...

What animals can tell us about hemorrhage, organ transplants and aging

...a lower metabolic rate. A study of birds, bats and rodents finds differences within their cells that may help explain the longer-than-expected life span of birds and bats, Kristan said. These are just two of the symposia taking place at the conference. There are plenty of fresh and interesting story line...

UWM brain research supports drug development from jellyfish protein

...rning and memory deficits. These tasks first teach rodents to associate one stimulus with another and then test their memory of the association. During training, the stimuli are separated by a brief period of time, which requires the animal to maintain a memory of the first stimulus. The "stimulus free" peri...

Mice learn tasks that may help treat human psychiatric disorders

...ed the outer texture and smell of the bowls. The rodents learned to find the cereal by using a cue such as the bowl's outer texture. After experience solving a number of tasks with this cue, the animals were given a new cue for finding the cereal, such as the bowl's smell. "Like people performing a serie...

Wild vs. lab rodent comparison supports hygiene hypothesis

In a study comparing wild rodents with their laboratory counterparts, researchers at... compares specific immune system responses of wild rodents to laboratory rodents, could open up a new approach to studying human disease and allergies that com...

BGSU biologist trying to crack microscopic code

...t" and a genetic model for 60 years, on a par with rodents in other research areas. The problem, however, is that laboratory E. coli are the "98-pound weaklings in the real world," not offering barriers as robust as other bacteria maintain outside the lab, he says. So he has begun studying the type of bact...

Pest control research leads to pain control discovery

...Bruce Hammock's lab, tested the novel compounds on rodents and found them to be as potent at a low-dose as Vi...lar or greater potency in reducing inflammation in rodents to Vioxx, but also when combined with Vioxx can dramatically reduce the concentrations of the Cox 2 ...

Possible brain hormone may unlock mystery of hibernation

... of Cell. Hibernation allows animals from bears to rodents to survive unscathed--in a state of suspended animation--under the harshest of winter conditions. If the findings in chipmunks are confirmed, the hormone would represent the first essential brain signal governing the seasonal adaptation, according t...

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