Man and mouse share genome structures
... the way chromatin is organized, thus allowing the right combination of genes to be turned on. In their study, the researchers analyzed the chromatin structure of the two shortest human chromosomes, numbers 21 and 22, containing about two percent of the human genome. They also sampled additional regions i...Timing is everything: First step in protein building revealed
...ing happening at the wrong time,or the lack of the right thing."As a result, Lorsch studies the timing of h...rses of cells. If theribosome doesn't start in the right place along a gene's instructions,it will make the wrong protein, which can kill the cell or lead to...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
...od is unlikely to lead to a reliable clinical test right away. After conducting repeated checks of the data that supported the test’s effectiveness, the researchers say their findings indicate that claims about the experimental protein-based assay are not biologically plausible. “We view this as a cauti......od is unlikely to lead to a reliable clinical test right away. After conducting repeated checks of the data that supported the test’s effectiveness, the researchers say their findings indicate that claims about the experimental protein-based assay are not biologically plausible. “We view this as a cauti...Cracking the olfactory code in bees
...od is unlikely to lead to a reliable clinical test right away. After conducting repeated checks of the data that supported the test’s effectiveness, the researchers say their findings indicate that claims about the experimental protein-based assay are not biologically plausible. “We view this as a cauti...Signaling protein builds bigger, better bones in mice
...od is unlikely to lead to a reliable clinical test right away. After conducting repeated checks of the data that supported the test’s effectiveness, the researchers say their findings indicate that claims about the experimental protein-based assay are not biologically plausible. “We view this as a cauti...U-M scientist to talk about tissue engineering at AAAS
... scaffold helps direct the engineered cells to the right place, then dissolves once the cells begin to generate to fill in the wound. "In certain kinds of defects, the body cannot heal itself and the body needs a jumpstart," Krebsbach said. To heal a large wound, like that created when a cancerous tumor i...Genome-wide mouse study yields link to human leukemia
...aningful in treating leukemia is a big step in the right direction." Grants from the National Cancer Institute and the Leukemia and Lymphoma Society supported the research. Additional co-authors from Ohio State include Li Yu, Chunhui Liu, Jeff Vandeusen, Brian Becknell, Zunyun Dai, Yue-Zhong Wu, Aparna R......like using the Hubble telescope of ocean acoustics right now,?says Clark. “The Navy had heard the whales for years but hadn’t focused on the significance of their low voices. To me it was like —ohmygawd!?/p> Access to the U.S. Navy’s underwater listening systems took researchers from fixed-point observ...Jefferson Virologists Coax HIV Out of Hiding
...e virus at bay,it’s still quite capable ?given the right opportunity ?of replicatingand wreaking havoc on the body’s immune system.Now, virologists at Jefferson Medical College, led by Roger J.Pomerantz, M.D., professor of medicine, biochemistry and molecularpharmacology and director of the Division of Inf...Purdue proves concept of using nano-materials for drug discovery
...lecules to pass. "This allows us to do separation right in the reactor, which means we can do reactions that could not be done before in such a small device. We can study membrane proteins in a fundamentally new way, which is very important because many future drugs to treat diseases will likely work by c......ese analogues into clinical trials. "We're trying right now to get a company interested in this, especially because the mice used in our trial seemed to experience minimal toxicity -- a good sign that patients might tolerate these compounds, too," Dr. Huang said. "It's all very exciting," he said. "Metas...Critical role in programmed cell death identified
...mmon safeguard, to ensure that neurons talk to the right neighbors and make the right connections." Also, if cells do not die on schedule, unregulated growth can lead to tumors and other...Open microfluidic and nanofluidic systems
...count. Such a contact line is visible in the upper right image in Figure 1. In such a situation, the contact angle is not determined by the classical Young equation but can vary over a wide range of values. A surprising prediction of the new theory is that the experimentally observed polymorphism of the w...Development of portable infectious disease detector
... to apply. Although Pria decided that he wasn'tthe right person for the job, in their correspondence Pyle expressedpotential interest in collaborating with VIIBRE. Schaffer passed theinformation along to Wikswo, who gave Pyle a call. That was in earlySeptember. By mid-November a joint research agreement fo...Why do insects stop 'breathing'? To avoid damage from too much oxygen, say researchers
...ernal oxygen concentration at 4-5 kilopascals, the right oxygen concentration for its body. In a low-oxygen environment, the insect opens its respiratory system for longer periods of time; when it closes the system, it does so for only a very short time. In a stream of air with high oxygen on the other han...Scientists discover unique microbe in California's largest lake
...ced theorganism's unusual lime-green color."I knew right away there was something unusual about itsphotochemistry," Miller recalls."We purified the pigments from the strain and saw that they were verysimilar to those known from a species of blue-green algae calledAcaryochloris marina, but different from an...First real-time view of developing neurons reveals surprises, say Stanford researchers
... moving in a certain direction or near the left or right side of the visual field. What they found was a surprise. As soon as the neurons were old enough to respond to the LCD screen, they specifically fired when they sensed only one type of movement. When the tiny square moved left to right, a distinct p...Gene vaccine for Alzheimer's disease shows promising results
...t least two years out,theoretically, we are on the right track," he said....Scientists identify molecular events that drive cell senescence
...t least two years out,theoretically, we are on the right track," he said....