Tag: "reversible" at biology news

Bone Density Recovers After Teens Stop Injected Contraceptive

...d and that bone density loss may not be completely reversible after discontinuation of the drug. The FDA warning states: “Depo-Provera Contraceptive Injection should be used as a long-term birth control method (e.g. longer than 2 years) only if other birth control methods are inadequate.?The black box warning ...

50-year-old Mystery Solved: Protein Tags Regulate Key Ion Channel

...he book of how cells control ion channel function: reversible peptide linkage." Ion channels are in every cell in the human body. They are tightly controlled tunnels through the membrane barriers that hold in the cell's contents, separating the cell from the outside world. Ion channels allow ions such as potas...

Buying Time Through Hibernation on Demand

...enter have, for the first time, induced a state of reversible metabolic hibernation in mice. This achievement, the first demonstration of "hibernation on demand" in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues. "We...

U-M team recovers ancient whale in Egyptian desert

...enter have, for the first time, induced a state of reversible metabolic hibernation in mice. This achievement, the first demonstration of "hibernation on demand" in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues. "We...

DNA constraints control structure of attached macromolecules

... macromolecules with DNA constraints can be either reversible or irreversible, depending on which chemical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constrain...

UN successfully tests 'green' pesticide against locusts

... macromolecules with DNA constraints can be either reversible or irreversible, depending on which chemical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constrain...

Health costs soar as 60 million Americans classed as obese

... macromolecules with DNA constraints can be either reversible or irreversible, depending on which chemical trigger is used. Like a switch, a particular molecular shape could be turned on and off. "Another key aspect of DNA constraints is their programmability," Silverman said. "By placing two or more constrain...

Investigating 'brain shrinkage' in alcoholics

...wever, the damage appears to be at least partially reversible with abstinence. "The aim of this symposium was t...een in cirrhosis of the liver are also potentially reversible if treated. Furthermore, thiamine deficiency can be treated easily with oral or injected thiamine. P...

Study shows eutrophic lakes may not recover for a millennium

... report says. "This type of eutrophication is not reversible unless there are substantial changes in soil management," Carpenter writes in PNAS. The amount of phosphorus that runs into the lake in any given year is small, the Wisconsin scientist notes, but a little bit of the nutrient is all that is needed to ...

Duke Experiments Boost Radiation's Cancer-Killing Effects

...sing it to the antibiotic tetracycline. With this reversible switch, the team could observe the effects while HIF-1 was active and when it was blocked. Drugs to block HIF-1 have been used in previous studies conducted at Duke and elsewhere, but such drugs inhibit other proteins as well, making it impossible to...

IBM Transforms the Art of Scientific Expeditions

...sing it to the antibiotic tetracycline. With this reversible switch, the team could observe the effects while HIF-1 was active and when it was blocked. Drugs to block HIF-1 have been used in previous studies conducted at Duke and elsewhere, but such drugs inhibit other proteins as well, making it impossible to...

Out of sight, out of mind? Not necessarily

... For the study, the researchers induced temporary, reversible blindness lasting only a fraction of a second in nine volunteers with normal vision. Transcranial magnetic stimulation (TMS), a harmless noninvasive technique using brief magnetic pulses, was applied to the volunteers' visual cortex -- the area at th...

Limiting the damage in stroke

...rated two additional mouse models, which allow the reversible repression or activation of IKK2 at any time in neurons. "The unique advantage of this system is that we can specifically induce or block this signaling pathway at virtually any time and selectively in neurons," Wirth emphasizes. Putting all of thi...

Hormonal male contraception reversible after few months for all men

... of THE LANCET highlight how such contraception is reversible within a few months. Currently available male contraceptive methods (condoms, withdrawal, and vasectomy) are not acceptable to many couples because they are either not sufficiently reliable or not easily reversible. In a similar way to ovulation sup...

Mice lacking social memory molecule take bullying in stride

...ry circuit. Yet, the social avoidance behavior was reversible by giving the animals antidepressants. Next, borrowing a page from gene therapy, the researchers injected mice with a kind of molecular magic bullet (using transgenic techniques and a virus) that selectively turned off BDNF expression in the social...

Quitting smoking improves lung function considerably

...said Dr. Thomson. "It demonstrates that there is a reversible component to the harmful effects of smoking on the airways in asthma." "The degree of improvement noted for smoking cessation far exceeds that of high-dose anti-inflammatory treatment, such as oral prednisolone, 40 mg daily for 2 weeks, which had ...

One signal elicits thousands of answers

...on via protein modifications, most importantly the reversible attachment of phosphate, the so-called protein phosphorylation. Researchers at the Max Planck Institute of Biochemistry in Martinsried have now developed a technology to identify and quantify the specific sites in proteins that get phosphorylated in ...

PET imaging shows young smokers quick benefit of quitting

...PET study that shows abnormal coronary function is reversible after only one month of smoking cessation," said Nagara Tamaki, a professor and chair of the nuclear medicine department at Hokkaido University in Sapporo, Japan. "Smoking cessation normalized abnormal coronary artery function, thus supporting its va...

NHGRI aims to make DNA sequencing faster, more cost effective

...r goal is to improve the chemical subunits, called reversible terminators, for use in a system that will ultimately be used to sequence DNA templates in high-density arrays, using a sensitive fluorescence detection system. Steven Jeffrey Gordon, Ph.D., Intelligent Bio-Systems, Inc., Worcester, Mass.,$425,00...

Prion disease treatable if caught early

...Mallucci and colleagues. "Our findings of early reversible neurophysiological and cognitive deficits occurring prior to neuronal loss open new avenues in the prion field," they wrote. "To date, prion infection in mice has conventionally been diagnosed when motor deficits reflect advanced neurodegeneration. N...

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