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Tag: "reverses" at biology news

Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems

..."Growth hormone/IGF-1 replacement in older animals reverses the age-related decline in cognitive function." The group also found that "cartilage degeneration that normally accompanies aging is accelerated by the absence of growth hormone." The researchers concluded that cancer risk as well as other age-rela...

Targeting a key enzyme with gene therapy reversed course of Alzheimer's disease in mouse models

...ecessary for the formation of the telltale plaques reverses the progression of the disease, and more importantly, the cognitive function of these mice, which had already been impaired, has now recovered," says Inder Verma, professor in the Laboratory for Genetics at the Salk Institute for Biological Studies. ...

Scientists create digital bacteria to forge advances in biomedical research

... in devising simulations to understand how the sun reverses its magnetic field every 11 years. Each digital cell in AgentCell is a virtual Escherichia coli, a single-celled bacterium, which is equipped with all the virtual components necessary to search for food. These digital E. coli contain their own chemo...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...lectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. It's published in...te, selectively enhances apoptosis in PAH and thus reverses PAH, prolonging the survival of rats. Because this oral therapy has already been tried in humans wit...

Experimental drug reverses key cognitive deficits, pathology in Alzheimer's

...cell receptor involved in Alzheimer's disease (AD) reverses learning and memory deficits in mice engineered to have pathological hallmarks of the disease. What's more, the drug, called AF267B, reduces both of the pathologies--the brain-clogging buildup of protein "amyloid plaque" outside brain cells and the p...

Drug triggers body's mechanism to reverse aging effect on memory process

...rigger a natural mechanism in the brain that fully reverses age-related memory loss, even after the drug itself has left the body, according to researchers at UC Irvine. Professors Christine Gall and Gary Lynch, along with Associate Researcher Julie Lauterborn, were among a group of scientists who conducted...

When it comes to gene transcription, random pauses aren’t quite so random, study finds

...ssociated with gene regulation in which the enzyme reverses direction briefly; or a "hairpin pause, " named for tiny hairpin-shaped structures that sometimes form when an RNA strand binds to itself. "Kristina made these totally cool DNA templates that have the same 240-base pair sequence repeated over and ov...

Gene linked to rare disease activates fat breakdown

...ving the CDS mutation restores lipid breakdown and reverses the abnormal triglyceride accumulation typical of patients with the lipid storage disease. "These data establish an important biochemical function for CGI-58 in the lipolytic degradation of fat, implicating this lipolysis activator in the pathogenes...

Gardenia fruit compound starting point for diabetes therapy

...ype 2 diabetes does indeed contain a chemical that reverses some of the pancreatic dysfunctions that underlie the disease, researchers report in the June 7, 2006, Cell Metabolism. The chemical therefore represents a useful starting point for new diabetes therapies, they said. Such a drug could offer a big ad...

Scientists find hormone activity explains adolescent mood swings

...ally released in response to stress, THP, actually reverses its effect at puberty, when it increases anxiety. This hormone normally acts like a tranquilizer, acting at sites in the brain that "calm" brain activity. In the adult, this stress hormone helps the individual adapt to stress, with a calming effec...

Clot-dissolving agent may be beneficial in treatment of severe frostbite

... blood vessels, leading to cell death. Because tPA reverses this clotting, blood flow is restored before permanent damage is done. “Based on the dramatic improvements in perfusion [blood flow] and reduction in rates of amputations when tPA was administered within 24 hours of frostbite injury, we anticipate...

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