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Tag: "reverse" at biology news

Nutrition a major factor in rise in twin pregnancies

...or culture conditions, it could prove difficult to reverse as embryo quality continues to improve ?whether in the IVF lab or in the community generally." "Because two implanted embryos have twice the chance of MZ twins than a single implanting embryo the best way of minimising MZ as well as DZ twinning is t...

Toxic molecule may cause most common type of muscular dystrophy

...isonous RNA (ribonucleic acid) in muscle cells can reverse myotonic dystrophy, the most common type of muscular dystrophy in adults. About 40,000 people in the United States have myotonic muscular dystrophy (MMD). The disease can cause a slow, progressive wasting of the muscles, irregular heartbeat, catara...

Parkinson's disease mechanism discovered

...rapeutic potential. "We have found compounds that reverse alpha-synuclein toxicity, and we plan to publish those results soon," she said. "These findings are exciting because they tell us we have a platform for discovering new therapeutic strategies and for speeding the process of discovering treatments for...

Brain enzyme treatment relieves memory lapse in Alzheimer's mice

...eimer's symptoms, the researchers found they could reverse lapses of memory characteristic of the debilitating disease. Treatments that elevate the protein, known as ubiquitin C-terminal hydrolase L1 (Uch-L1), might therefore have potential as a new therapy for Alzheimer's disease, according to the researc...

Pest control research leads to pain control discovery

...response to a painful stimulus. The sEH inhibitors reverse hyperalgesia and bring their withdrawal reaction back into the normal range. Hammock said "these sEHIs are of similar or greater potency in reducing inflammation in rodents to Vioxx, but also when combined with Vioxx can dramatically reduce the con...

Drug triggers body's mechanism to reverse aging effect on memory process

...researchers showed that ampakine drugs continue to reverse the effects of aging on a brain mechanism thought to underlie learning and memory even after they are no longer in the body. They do so by boosting the production of a naturally occurring protein in the brain necessary for long-term memory formation....

Carnegie Mellon researchers discover new cell properties

...d what causes the lamina to stiffen, we can try to reverse or stop the problem," Dahl said. "We think this stiffening mechanism happens over time with increased protein concentration, so we need to determine the tipping point that causes real problems." When people grow old, the walls of the cell nuclei exh...

UF scientists test improved gene therapy method for hereditary heart conditions

... UF researchers used the approach to successfully reverse symptoms in mice with a form of muscular dystrophy that damages the heart. They also tested the virus-based delivery method in monkeys and found genes were readily absorbed by heart muscle cells, and the effect persisted for months. The findings, p...

New human retrovirus originated in mice

...ic material is in the form of RNA. The RNA is then reverse transcribed into DNA that is integrated into the DNA of the host cell the virus is infecting. When the researchers isolated and sequenced the genome of the virus, they found that it was a xenotropic virus ?one that can only grow in foreign cells oth...

New fruit fly protein illuminates circadian response to light

...response to light. Sehgal and others were able to reverse the behaviors in the jetlag flies by genetically replacing the mutated gene sequence with the normal sequence, which led to the production of the wild-type (control) JET protein. When the jetlag flies acquired the normal JET protein, regular TIM degr...

Biomarkers may hone anti-aging therapies

...ancer, and for screening compounds that prevent or reverse the process, Sligh said. ...

Anti-inflammatory drug's potentially deadly side effect found to be rare

...gresses to death within a few months unless we can reverse the immune suppression." MS is an autoimmune disease believed to result from misguided immune system attacks on nervous system tissues. It comes in various forms and affects an estimated 400,000 Americans, with 200 new diagnoses of MS every week. R...

Thinner and younger

... "We want to learn whether calorie restriction can reverse some of these markers of aging in healthy young people," Holloszy says. "It's going to be many years before we know whether calorie restriction really lengthens life, but if we can demonstrate that it changes these markers of aging, such as DNA damag...

Mayo Clinic researchers challenge sepsis theory

...iscover new therapies that could prevent, blunt or reverse the release of the constrained receptor. ...

Rewind, please: Nature paper shows that cell division is reversible

...ma Medical Research Foundation, has found a way to reverse the process of cell division. The discovery could...esponsible for the division process, interrupt and reverse the event, sending duplicate chromosomes back to the center of the original cell, an event once thou...

MIT research holds promise for Huntington's treatment

...eatments have focused on compounds that prevent or reverse the aggregation of huntingtin proteins. However, recent evidence suggests that the largest inclusions may not necessarily be harmful and could in fact be protective, said Bodner. So, the MIT and Harvard scientists decided to look for compounds that a...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...lass of drugs called non-nucleotide inhibitors for reverse transcriptase typically bind at such alternate sites." Once Perryman had a hypothesis to test in a second round of simulations -- the proposed mechanics of the protease enzyme's nanomachinery--he used artificial restraints in the computer program to...

Report shows deforestation threatens Brazil's Pantanal

...ccording to the report, urgent actions required to reverse the situation include increased government regulation and better coordination of conservation efforts at various government levels (municipal, state and federal); a review of current legislation regarding protected areas and legal reserves for the re...

Computer simulation hints at new HIV drug target

...lass of drugs called non-nucleotide inhibitors for reverse transcriptase typically bind at such alternate sites." Once Perryman had a hypothesis to test in a second round of simulations -- the proposed mechanics of the protease enzyme's nanomachinery--he used artificial restraints in the computer program to...

Insects and mammals share common fat-building pathway, study suggests

... that stimulate the pathway could possibly help to reverse or prevent this trend, building stronger bones while reducing fat." The researchers found that flies in which the Hh pathway in the fat bodies was overactive gained less fat than normal. Conversely, treatments that blocked the action of the Hh pathw...

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