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Tag: "reveal" at biology news

Heart failure: Intervention possibilities from imaging programmed cell loss

...three-dimensional computer-reconstructed images to reveal information about both structure and function to measure the amount of annexin A5 absorbed. Annexin A5 bound to the damaged heart muscle. "We discovered that higher uptake was uptake with a worse outcome. Cell death is one of the biological events th...

Bacterial walls come tumbling down

...ffract x-rays into a pattern that would ultimately reveal its natural structure. They then were able to repeat the feat to reveal the crystal structure of the enzyme combined with the animal antibiotic. Their findings help reve...

A genetic 'gang of 4' drives spread of breast cancer

...ies by Howard Hughes Medical Institute researchers reveal that the aberrant genes work together to promote the growth of primary breast tumors. Cooperation among the four genes also enables cancerous cells to escape into the bloodstream and penetrate through blood vessels into lung tissues. Although shutti...

Researchers find gene mutation that causes infertility in male mice

...had a custom gene "knockout," this is the first to reveal a dominant mutation that leads specifically to infertility in a mammal. The researchers believe this kind of dominant effect is closer to how real-life infertility occurs in humans. "People have been sequencing genes in humans, including the Dmc1 g...

Renegade RNA -- Clues to cancer and normal growth

..., Mendell hopes that further study of miR-29b will reveal other, hidden functions of microRNAs. ...

Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex

... and, in a second step, isolated and fragmented to reveal their amino acid sequence. Using this two-step, or tandem (MS/MS), procedure, Asara netted seven separate strings of amino acid. He now faced his second challenge, namely, to interpret the amino acid sequences. Normally, when a sequence comes out ...

Secret of worm's poison pill box protein could produce new natural insecticide

...al research arm Warwick HRI, have now been able to reveal the shape of the protein XptA1 and discovered a number of properties that make it a particularly efficient natural insecticide and possible alternative to some commercial insecticides that are facing increased resistance in the insect populations t...

Wired for sound: How the brain senses visual illusions

In a study that could help reveal how illusions are produced in the brain's visual c... signals, when only one flash actually occurs ?can reveal how information from different senses are integrated in the brain. The study of 34 subjects was...

Technology reveals 'lock and key' proteins behind diseases

...this process." iMYTH works by scanning cells to reveal proteins that fit with the transporters, the only ...entifying new interactors for ABC transporters may reveal unanticipated aspects of how these transporters function and help researchers gain clues for fightin...

Angelman syndrome deficits rescued in mice

... Nature Neuroscience (currently available online), reveal an important part of the mechanism underlying the condition and point to potential therapeutic targets for treating these symptoms. Angelman syndrome, which affects approximately one in 15,000 children, is a debilitating neurological disorder char...

MicroRNAs as tumor suppressors

...G&D, Drs. Yong Sun Lee and Anindya Dutta (UVA) reveal that microRNAs can function as tumor suppressors in vitro. "Overexpression of HMGA2 is an important feature of many medically important tumors like uterine fibroids,?explains Dr. Dutta. “It is very exciting to realize that microRNAs have an importa...

Ancient amphibians evolved a bite before migrating to dry land

... -- in the tops of these fish and amphibian skulls reveal how these extinct animals captured prey, say authors Molly J. Markey and Charles R. Marshall. "Based on experimental data obtained from living fish, we found that the shapes of sutures in the skull roof indicate whether a fish captures its prey by...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...new high-throughput genetic analysis technique can reveal gene markers ?by the dozens ?that determine how a ...ave revealed several sensitizing drug targets that reveal a set of candidate combination drugs that are predicted to be synergistic with Tykerb." Tykerb ...

Out of Africa -- Bacteria, as well

...enes of bacteria isolated in Europe, for instance, reveal influences from Central Asia - an indication that human immigrants came to Europe from Asia. ...

Researchers discover new details about HIV-1 entry and infection

...fore spreading it to other cells. These results reveal that it is necessary to consider mechanisms of viral entry into both CD4+ T and LC when searching for an effective way to interfere with infection through the vaginal epithelium. "Our findings provide exciting definitive insights into the initial eve...

Scientists discover a new risk factor for Alzheimer's

... sets that St George-Hyslop's team studied did not reveal a significant association between SORL1 and Alzheimer's. Non-SORL1 causes might have been overrepresented and SORL1-associated causes underrepresented in these data sets, St George-Hyslop explained. Alternatively, these data sets may have contained s...

UF scientists discover new genus of frogmouth bird in Solomon Islands

...ion of detailed morphological and genetic analyses reveal that this frogmouth ?formerly dismissed as just a race of an existing species ?actually cannot be placed confidently in any existing genus, and so the data demand naming a new one." Storrs Olson, a senior zoologist with the Smithsonian Institution...

Discovery of an HIV inhibitor in human blood points to new drug class

...t," according to the researchers. "The findings reveal a new target for inhibiting HIV that remains fully active against viral strains that are resistant to other drugs," said study author Frank Kirchhoff of the University of Ulm in Germany. "That's a big advantage." Kirchhoff's group also provided ev...

The origin of the brain lies in a worm

...ecular Biology Laboratory (EMBL) in Heidelberg now reveal that the vertebrate nervous system is probably much older than expected. The study, which is published in the current issue of Cell, suggests that the last common ancestor of vertebrates, insects and worms already had a centralised nervous system res...

Studies yield insight into the numerical brain

...t symbols precisely with quantities. Both studies reveal in unprecedented detail how structures in the parietal cortex--the region of higher cognitive processing just above the forehead--activates during perception of both abstract quantities and numerical symbols. In one paper, Manuela Piazza and collea...

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