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Tag: "responsible" at biology news

Novel vaccine shows promise against early-stage breast cancer

...ease. Targeted immunoediting of critical pathways responsible for breast cancer development: treatment of early breast cancer using HER-2/neu pulsed dendritic cells Multiple genetic targets have been discovered that may help fight breast cancer, including BRCA, estrogen receptors, and HER-2/neu, all of which...

Study illuminates how the plague bacteria causes disease

The bacteria responsible for the plague and some forms of food poisoning "p...the virulence of Yersinia--a bacteria historically responsible for some of the worst diseases," he added. Although improvements in sanitation have eliminated acute...

From a lowly yeast, researchers divine a clue to human disease

...edicine and Public Health. A host of proteins are responsible for controlling which genetic messages are read and how much of the information is used. Working with yeast, Brow and his colleagues show that a protein called Sen1 plays an important early role in this process. Mutations in the human version of S...

Study IDs protein that inhibits HIV from growing in cell cultures

...ell culture strengthens the argument that GBV-C is responsible for the prolonged survival observed in several studies of HIV-positive people," Xiang said. "Understanding how the protein works may allow us to develop target-specific therapies that can mimic these effects and inhibit HIV. "Potentially these nov...

Wild gorillas carriers of a SIV virus close to the AIDS virus

...ing with HIV. The question of the origin of HIV-1, responsible for the AIDS pandemic, has been stimulating the scientific community for many years. Some months ago, the team of Martine Peeters, director of research at IRD, and Eric Delaporte, director of the mixed research unit UMR 145 jointly involving the IRD...

Researchers in Montréal and the US create model of key immune-system component

...n of the phagosome. The phagosome is the organelle responsible for the destruction of infectious pathogens that cause such diseases as tuberculosis and salmonellosis, as well as pathogens that could be used in bioterrorism. The results of their study were published this week in the prestigious journal Nature. ...

New sunscreen ingredient to heal sunburn and help prevent skin cancer

...e outer layer of the skin and is the primary agent responsible for skin blistering and peeling after sunburn. "UVA sunlight is typically associated with the cooler parts of hot summer days, before 10am and after 3pm. "UVA was once thought to have a minor effect on skin damage, but now it is considered to be...

A key antibody, IgG, links cells' capture and disposal of germs

...ost destructive microbial pathogens, such as those responsible for tuberculosis and salmonellosis, are able to hijack cells and use them as a breeding ground precisely because they block the merger of phagosomes and lysosomes. It had long been known that coating these germs with IgG can restore their destruction...

Scientists discover toxin that causes gastro disease

... strains of E. coli bacteria, has been found to be responsible for an outbreak of haemolytic uraemic syndrome, a dangerous disease that causes acute kidney failure, in South Australia in 1998. The research team was led by Dr Adrienne Paton from the University of Adelaide, and included scientists from Monash ...

HIV gets a makeover

...ng just a few parts of the human virus -- the ones responsible for blocking replication in monkey cells -- with components from SIV. "Overall, the virus is a mixture of engineering and forced evolution," Bieniasz says. "It sounds simple, in theory, but it took us two years to do." Bieniasz and Theodora Hatzii...

Technology exists to keep E. coli out of food

...ables, destroying bacteria like the E. coli strain responsible for the spinach/green onion outbreaks. This system could be used from the farm to the retail market—for irrigation in fields, washing in processing plants and misting in grocery stores. "The results we're seeing are phenomenal. It's killing all ...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...y ultimately derive the most benefit," says senior responsible author Abdallah Daar, Director of Ethics and Policy of the U of T McLaughlin Centre for Molecular Medicine. "While there are no easy solutions to the complex challenges facing developing countries, these technologies offer real promise in the field ...

Geneticists discover genes that make fruit fly hybrids sterile

...ication of a pair of genes in any species that are responsible for problems unique to hybrids. Specifically, the researchers have found two genes from two fruit fly species ( Drosophila melanogaster and D. simulans ) that interfere with each other, thereby preventing the production of male offspring. The fin...

Hormone linked to brain's cravings for food and other energy sources

...cuitry of the ventral tegmental area (VTA), may be responsible for overeating and addiction. "Targeting this region pharmacologically is an interesting tool to explore," said Horvath, chair of the Section of Comparative Medicine at Yale School of Medicine and professor of comparative medicine, neurobiology and o...

Did 'ABCs' cause Uganda's fall in HIV rates?

...s, the ABC approach is sometimes credited as being responsible for Uganda's dramatic decline in HIV rates. A provocative debate in PLoS Medicine considers the two sides to the question of whether the ABCs are helpful or harmful in the battle to control the HIV pandemic. Elaine Murphy and Margaret Green (George...

Tulane researcher reports on origin of deadly fever outbreak

Bats or other cave dwelling animals may have been responsible for the deadly 1998?000 outbreak of Marburg hemorrhagic fever among gold miners in the Democratic Republic of the Congo, according to an article in the Aug. 31, 2006, issue of the New England Journal of Medicine. Daniel G. Bausch, associate profess...

High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping

...umors (GISTs), and certain EGFR mutations that are responsible for one form of lung cancer. These cancers can be treated with the targeted therapies Gleevec and Tarceva, respectively, which shut down the affected oncogenes. The test involves taking a sample of fresh or frozen tumor, amplifying its DNA, and then...

Molecular 'signature' protects cells from viruses

...eolus.' These RNAs do not store information, being responsible for important tasks in 'assembling' the proteins. Importance for therapy The fact that RNAs without a 'signature' stimulate an immune reaction and initiate cell suicide opens up completely new perspectives for the therapy of virus infections an...

Biologists probe the machinery of cellular protein factories

...osed in the early 1970s that the RNA component was responsible for carrying out the ribosome's key functions. At the time it was considered a "crackpot idea," but subsequent findings by Noller and others proved he was right. "It was a completely heterodox view when we first proposed it, but it is now the acce...

Nanotech tools yield DNA transcription breakthrough

... The researchers showed that the molecular machine responsible for transcription unwinds adjacent DNA segments and pulls unwound DNA into itself during initial transcription ("scrunching"). In addition, the researchers showed that machine rewinds this unwound DNA when the machine leaves the start site and be...

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