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Tag: "responsible" at biology news

Study uncovers mutation responsible for Noonan Syndrome

...of severe cases] the identity of the gene or genes responsible for fully half the cases had not been elucidated," Neel said. To identify candidate genes, a group led by HMS instructor Amy Roberts, MD, and director of HPCGG Raju Kucherlapati, PhD, conducted genetic analysis of over 100 children with Noonan syn...

An AIDS-related virus tricks cells to become tumors, new Penn study finds

...efore it can start the process of activating genes responsible for inducing growth of more blood vessels to supply the tumor with oxygen. However, in a KSHV-infected cell, p53 and VHL themselves would be targeted for degradation and HIF-1a would then be free to activate genes involved in growth of blood vessels ...

Hair-growth drug artificially lowers PSA levels in prostate cancer screening, study finds

...wn for years that the same testosterone metabolism responsible for prostate growth also causes male-pattern baldn...e named 5-alpha reductase. DHT activates the genes responsible for the development of male-pattern hair loss. Finasteride interferes with this process by blocking ...

Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia

...ia. Chlamydia trachomatis is a bacteria that is responsible for a common STD. If untreated, Chlamydia infections can damage a woman's reproductive organs and lead to infertility. An estimated 2.8 million men and women in the U.S. are infected with chlamydia each year. Chlamydia can be easily treated and cured...

Eating protein boosts hormone that staves off hunger

...nd weight loss maintenance. However, the mechanism responsible remained elusive. In a study in normal-weight and obese people, the researchers now show that enhanced-protein meals stimulate greater release of PYY than either high-fat or high-carbohydrate meals and result in a greater reduction of hunger. Fur...

A silent pandemic: Industrial chemicals are impairing the brain development of children worldwide

...d Landrigan conclude that industrial chemicals are responsible for what they call a silent pandemic that has caused impaired brain development in millions of children worldwide. It is silent because the subclinical effects of individual toxic chemicals are not apparent in available health statistics. To point ou...

HIV-1 kills immune cells in the gut that may never bounce back

... percent of its CD4 memory T cells -- immune cells responsible for recognizing invaders and priming other cells for attack. Intrigued, Martin Markowitz, an Aaron Diamond Professor at Rockefeller University and a staff scientist at ADARC, wanted to know whether this loss was reversible, and whether giving patient...

Researchers identify neurons that assign value during learning

...ntify neurons in the fruit fly Drosophila that are responsible for assigning value to stimuli during so-called as...monstrate that antagonistic subsets of neurons are responsible for assigning positive or negative values to odor stimuli. It will be of interest to see whether thi...

Who gives stem cells their marching orders?

...a single gene involved in embryonic development is responsible for two seemingly contradictory activities -- maintaining stem cells after the embryo has implanted in the mother's uterus, and later providing cues to direct their differentiation in a coordinated fashion when the time is ripe. The development of ...

Scientists crack genetic secrets of human egg

...ology and animal science. "Some of those genes are responsible for the magic trick that the egg has. This paper takes a peek at what genes are in the egg waiting to make these changes." Combined with sperm, the egg divides and organizes cells to ultimately create a human being. Combined with technology, the...

Origin of inherited pain disorder pinpointed

...ases, indeed, revealed that mutations in SCN9A are responsible for the disease in at least two-thirds of PEPD cases. Analysis of these mutations revealed that they all disrupted the ability of the sodium channel to rapidly snap shut, prolonging activation of the peripheral nerves in which the channels function...

Molecules in blood foretell development of preeclampsia

...alance of two proteins produced by the placenta is responsible for the symptoms of preeclampsia. Abnormally high levels of these proteins appear to deprive the blood vessels of substances needed to keep the lining of the blood vessels healthy. Deprived of these essential substances, the cells lining the blood ...

Cocaine high caused by interference in neuronal receiving stations

... D2R, tended to attach to the NR2B subunit and was responsible for preventing the normal activation of the glutam...n the striatum of the brain—the region known to be responsible for cocaine's stimulating effects. The researchers also analyzed whether this interaction between ...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...tem's B cells and causes them to grow, is directly responsible for Burkitt's lymphoma, an often-fatal malignancy ...d that one 25-amino acid segment within EBNA-1 was responsible for the regulation of viral gene transcription, the first step in the process by which a gene's code...

Environmental toxins may cause body's defenses to worsen lung disease

...e in the lung. Lymphocytes, the white blood cells responsible for targeting and fighting off infection in the body, continually survey the epithelial cells lining the lungs to identify and destroy diseased cells. If the lymphocyte recognizes the tissue, Borchers explains, it simply continues its survey for prob...

Train your brain to hear your friends at a party

...e in a noisy place, such as a party or bar, and is responsible for "training" the brain to hear better in these s...ying to work out exactly what part of the brain is responsible and how it allows us to distinguish one sound from lots of noise. Early research has had some remark...

Studies find general mechanism of cellular aging

...unction of pancreatic islet cells. Islet cells are responsible for insulin production and secretion. Because p16INK4a stops cancer cells from dividing and demonstrates increased expression with age, the scientists suspected the gene played a similar role in aging. The researchers developed strains of mice that w...

Memories: It's all in the packaging, scientists say

...he parietal cortex. It appears that this region is responsible for binding together all the features of a particular memory so that contextual details, as well as more central aspects of the event such as the identity of the word, can later be recalled. "We know that if the intra-parietal sulcus is damaged, t...

Mysterious 'neural noise' actually primes brain for peak performance

...estions--how can it be that our neurons, which are responsible for our crystal-clear thoughts, seem to fire in utterly random ways? In the November issue of Nature Neuroscience, the Rochester study shows that the brain's cortex uses seemingly chaotic, or "noisy," signals to represent the ambiguities of the real...

Genetic surprise confirms neglected 70-year-old evolutionary hypothesis

...nto two new species. When asked if JYAlpha may be responsible for melanogaster and simulans' initial split a few million years ago, Masly replied, "That's lost to history." Fortunately, the theory isn't. ...

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