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Tag: "responsible" at biology news

Hybrid molecule causes cancer cells to self-destruct

...hile butyrate orchestrates the expression of genes responsible for halting the uncontrolled growth of cancer cells. Although the study of the exact molecular mechanism is in its early stages, the researchers believe the separate chemical components work together to bolster the cancer-fighting power of butyra...

Loss of a universal tRNA feature reported

...sfer RNA molecule tRNAHis. tRNAs are the molecules responsible for decoding sequence information specified by messenger RNA molecules, information which is ultimately encoded by the DNA template. tRNAHis is the specific tRNA that assists in incorporating the amino acid histidine into new proteins. Histidine re...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

...amine the genes of Cytophaga hutchinsonii that are responsible for the organism's ability to digest cellulose ?the first step in the carbohydrate's conversion into ethanol. Sequencing the genome of C. hutchinsonii provides what McBride calls a "parts list" for the microbe, allowing scientists to explore how ba...

Genetic pathways to curable and incurable forms of pancreatic cancer identified

... sequence of otherwise common genetic mutations is responsible for sending cells down the less-traveled path toward cystic pancreatic cancer versus the well-traveled route to the more fatal form of ductal pancreatic cancer. Sunil Hingorani, M.D., assistant member of the Hutchinson Center's Clinical Research a...

Bacteria control how infectious they become, study finds

...hird that appears to be the portion of the protein responsible for controlling the genes that make E. coli infect...ecting any living being. “We think that RfaH is responsible for more than making a microbe infectious,?he continued. “Actually seeing what happens at the molecu...

Technology reveals 'lock and key' proteins behind diseases

...sity of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications. A study appearing in the April 13 issue of Molecular Cell describes how U of T and Johns Hopkins University researchers designed a device to test f...

New mechanism for nutrient uptake discovered

... scientists, with colleagues, identified the genes responsible for initiating nitrogen uptake in plants. That identification has helped other researchers find the relatives of these genes in a variety of species from bacteria to humans. In this study, the scientists wanted to identify how ammonium transport is r...

Manipulating nature: Scientists query wildlife birth-control method

...reasons," Professor Cooper says. "If so, the genes responsible for this lack of response will be passed on to offspring. Within a few generations most of the population will be unresponsive to the immunocontraceptive, so its effectiveness as a form of birth control is likely to be short-lived." Professor Coop...

New study sheds light on 'dark states' in DNA

...see that there is a family of energy states in DNA responsible for energy dissipation, and this is a major correction in how we view DNA photostability." Until now, the proposed dark energy state of DNA was a little like the dark matter in the universe ?there was no direct way of probing it. The Ohio State che...

Fighting to keep Darwin in the classroom

...gh lectures, articles and books and is the curator responsible for the content of the major exhibition Darwin which opened at the AMNH in New York in November 2005, drawing in over 500,000 visitors. Greg Eldredge has a Masters Degree in Education and has been a New York City school teacher for the past three ye...

ESA launches new project to protect biodiversity

..." the UNCBD's Höft said. "It also demonstrates the responsible role of the private sector in offering tools and services for the benefit of the global community." ...

Keeping the body in sync -- The stability of cellular clocks

...cal model that identified the molecular parameters responsible for the stability of the cellular clocks. Stability is a measure of how fast the system reverts to its initial state after being perturbed. “To my knowledge we are the first to discuss how the stability of the oscillator directly affects biolumin...

MicroRNAs as tumor suppressors

...ausation and perhaps the cure of a disease that is responsible for the vast majority of hysterectomies in the Western world." Studying chromosomal HMGA2 translocations that are associated with human tumors, the researchers found that in normal cells, a microRNA called let-7 binds to the 3?end of the HMGA2 mRN...

Surgeons develop simpler way to cure atrial fibrillation

...on lines redirect the abnormal electrical currents responsible for atrial fibrillation, an irregular heart rhythm in which the upper heart chambers or atria wriggle like a bag of worms. The Cox-maze procedure was developed at the University in 1987. In their latest clinical study, reported in the February iss...

Protein overexpression at heart of heart failure

...nit of the L-VDCC complex (beta 2-subunit) that is responsible for the altered channel behavior in human heart failure. Similar changes of both beta-subunit expression and single-channel behavior were also observed in a mouse model of heart failure with cardiac overexpression of the human L-type Ca2+-channel por...

Protein discovery targets antibiotic-resistant bacteria

...anism that causes salmonellosis is related to that responsible for typhoid fever ?a huge problem in less developed countries ?the model being developed at Queen’s could potentially be a target for treating typhoid as well. The underlying goal is to control, if not clear, the infection. “It’s basic science tha...

Scientists discover new life forms in the Arctic Ocean

...lex biodiversity." The other members of the team responsible for this discovery are Fabrice Not, Khadidja Romari, and Daniel Vaulot from Université Pierre et Marie Curie (France); Klaus Valentin, Kerstin Töbe, and Linda Medlin from the Alfred Wegener Institute for Polar and Marine Research (Germany); and Ramon...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

...ver viruses, as well as the influenza virus strain responsible for the 1918 flu pandemic ?the immune system itself actually becomes the most dangerous element of the disease. All too often, a sudden immune overreaction sends the infected person into a shock-like state from which he or she may never recover. N...

Exploring the molecular origin of blood clot flexibility

...sses at the molecular and fiber levels that may be responsible for the mechanical properties of clots to eventually develop a model that can then be used to predict the effect of changes at one scale on clot properties at other scales. Such a model should be useful for developing prophylactic and therapeutic tre...

Researchers create artificial enzyme that mimics the body's internal engine

... cytochrome c oxidase (CcO) is the ultimate enzyme responsible for all aerobic life on Earth, from bacteria to people. It is also a crucial component of the cellular machinery that generates energy in our body. With such impressive credentials, you might expect that scientists would have a clear understanding of...

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