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Tag: "responsible" at biology news

New engineered drug may offer prolonged arthritis relief

...iginal or the modified drug. White blood cells are responsible for mounting the body's immune response and normally react to IL-1 by growing in numbers and releasing molecules that further activate the immune system. Active IL1RA therefore serves to dampen the immune cells' rate of proliferation, Shamji said. ...

New dyslexia theory blames 'noise'

...erling and Lu's data suggest is that the mechanism responsible for faulty phonological development is quite general and has to do with attention in a broad sense.... "This is a great paper of very high significance... As people like Steve Grossberg [of Boston University] have argued for many years, attention ...

Human stem cells delay start of Lou Gehrig's disease in rats

...les above the waist, especially those in the chest responsible for breathing, were not helped by these transplanted stem cells." The research team used so-called SOD-1 rats, animals engineered to carry a mutated human gene for an inherited form of ALS. As in human ALS, the rats experience slow nerve cell de...

UCLA researchers unravel a mystery about DNA

...f the structure and mechanics of RNAP -- an enzyme responsible for making RNA from a DNA or RNA template -- can help set the stage for new opportunities in combating bacterial diseases that kill 13 million people worldwide each year. The researchers used single-molecule spectroscopy to monitor the transfer of ...

Friendly bacteria in alcoholic milkshake could fight food allergies

...e presence of allergens it can also activate cells responsible for the release of histamine, a chemical which sti...ill microbes such as 'flu viruses and the bacteria responsible for MRSA. The system could be used to sanitize the air in airplanes and hospital sick bays. ...

Researchers image molecular motor structural changes

...esearchers said. For example, molecular motors are responsible for dividing genetic material during cell division, and understanding how motors work in cancer cells, which undergo unchecked cellular division, might lead to new anticancer therapies. The team, from Duke University Medical Center, the National Ins...

Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes

...udy of more than 2,000 Air Force veterans who were responsible for spraying herbicides including Agent Orange dur...c substances known and are thought to be partially responsible for this increase in male reproductive tract disorders. They are formed as byproducts of processes s...

Stanford discovery may help predict when toxoplasma can be deadly

...e Dec. 15 Science, searched for the gene or genes responsible for markedly increased virulence. To do such a survey, however, the researchers needed to produce an array of strains. Because Toxoplasma strains only recombine in cats, the researchers provided mice infected with different Toxoplasma strains f...

Researchers create genetically matched embryonic stem cells for transplantation

...tem cells that shared with the egg donor the genes responsible for tissue matching, called the major histocompatibility complex (MHC). When they injected these selected embryonic stem cells into MHC-matched mice, a variety of specialized tissues formed, with no rejection and no need to suppress the recipients' i...

Experimental cancer drugs counter muscle deterioration seen in muscular dystrophy

...d, caused by a mutation in one of a group of genes responsible for maintaining muscle integrity. Puri's team studied the disease's most common form, Duchenne muscular dystrophy, which affects one in 3,500 male births, according to the National Institute of Neurological Diseases and Stroke. Inheritance is linked ...

Researchers barcode DNA of Venice museum's vast fungi collection

... from Europe to the United States. The pathogen is responsible for sudden oak death, the disease that has caused widespread dieback of tanoaks and coast live oaks in California and southwest Oregon. "In the case of exotic plant diseases, DNA information may be used, as it is in criminal forensics, to identify...

Cellular traffic backups implicated in skeletal malformations

...cted that these so-called 'housekeeping genes' are responsible for that sort of phenotype." "For me, it's fascinating that the gene we have found was the least expected." It turns out that the zebrafish mutant has a human counterpart, making the crusher mutant the first animal model that links ER to Golgi pr...

Pair of microRNA molecules controls major oncogene in most common leukemia

...croRNA (miRNA) molecules help control the oncogene responsible for a dangerous form of B-cell chronic lymphocytic leukemia (B-CLL), the most common human leukemia in the world. Their findings, published in the December 15 issue of Cancer Research, demonstrate that miRNAs are emerging as powerful regulators of ...

Molecular mechanism provides intra-cellular traffic signal

...n brain disorders." A special set of proteins is responsible for the coordination. Molecular switches that go by the letters Ypt allow membrane-enclosed vesicles to pass in and out of cellular compartments. Activator proteins flip the switches on. One activator protein, called TRAPP, coordinates two Ypt switch...

Professors to develop hand-held pathogen testing device

...mful. For instance, the bacterium Vibrio cholerae, responsible for the waterborne illness cholera, has many housekeeping genes that maintain the organism, but are not dangerous to humans by themselves. But the gene producing the cholera toxin is harmful. These genes serve as good markers for detection. Hashsham'...

How brain injury leads to seizures, memory problems

... Transportation accidents such as car crashes are responsible for the majority of TBIs in people under age 75. According to the National Institutes of Health, over 5 million Americans currently have permanent disabilities resulting from TBIs. The study, which was done in animals, appears in the journal Neuro...

Critical hearing gene helps send auditory messages to brain

...ppeared to develop normally. "Study of the genes responsible for deafness can bring new insight into the molecular basis of how hearing works," said Christine Petit of the Institut Pasteur in Paris, France. The sensory machinery within the inner ear is particularly intriguing, she added, "in the sense that i...

A wolf in sheep's clothing: Plague bacteria reveal one of their virulence tricks

...ed Yersinia, a group that also includes a pathogen responsible for food poisoning. These bacteria insert into their host cells proteins and other virulence factors, which kill by -- among other things -- disrupting the cells' normal structure. One of these proteins, called YpkA, attacks a cell's internal skeleto...

High levels of blindness in southern Sudan following years of war

...es. Trachoma, which is caused by an infection, was responsible for a greater proportion of the cases of blindness than has been found in studies in other parts of rural Africa. In a second survey in the same district, the researchers looked specifically for cases of trachoma, both in its early stages and late...

New technology used to construct the first map of structural variation in the human genome

...ed article appears in Nature Genetics . CNVs are responsible for genetic changes in Alzheimer's and Parkinson's, susceptibility to HIV-1, some forms of color blindness, and many other diseases. They lead to variation in gene expression levels and may account for a large amount of phenotypic variation among in...

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