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Tag: "responsible" at biology news

Scratch no more: Gene for itch sensation discovered

...w of pain research, and no one knew which gene was responsible for itching in the brain or in the spinal cord until now." In fact, Chen's team became interested in GRPR because they were looking for genes in the pain pathway. Among potential pain-sensing genes they identified, GRPR stood out because it is prese...

One species, many genomes

... other organisms, on the other hand, such as those responsible for defense against pathogens or infections, are much more variable than the average gene. "The genetic variability appears to reflect adaptation of local circumstances," says Weigel. It is likely that such variable genes allow plants to withstand dr...

Identified main genetic variants involved in response to HIV

...recisely, these variations are in a genetic region responsible for the determination of immune response capacity ...nes controlling HLA-B and HLA-C molecular systems, responsible for the activation of the immune system so that it is able to locate and destroys cells infected by ...

The insect vector always bites twice

... Nile disease illustrate the trend. The pathogens responsible for these diseases can be viruses, bacteria or pro...tract of Glossinia flies, the immunogenic proteins responsible for synthesis of these specific antibodies (2). The different saliva proteins of four Glossinia spec...

Dirty snow may warm Arctic as much as greenhouse gases

...e gases, which trap outgoing energy, are primarily responsible for the remaining temperature increase and are considered the Earth’s most important overall climate changing mechanism. Other human influences on Arctic climate change are particles in the atmosphere, including soot; clouds; and land use. Humans ...

Largest synthetic gene ever built offers insights into anti-malarial drug resistance

...to Roepe. Five infect humans, but P. falciparum is responsible for about 1 million deaths out of 300 million acut...described in 2000 that the PfCRT gene is primarily responsible for the vast majority of drug resistance that leads to human death from malaria. Earlier this year, ...

Ancient DNA traces the woolly mammoth's disappearance

... than human causes, even if humans might have been responsible for killing off the small, terminal populations that were left.” Barnes, along with Dr. Adrian Lister of the University College London and the Natural History Museum in London and others, had earlier found evidence that bison, bears, and lions und...

Stroke study sheds light on left-right brain divide

..., the front part of the brain which is known to be responsible for aspects of language, decision making and learning. The team found that people who had damage to their left side were more likely to realise they had made a mistake, and then correct it, compared to those who had damage to their right frontal lobe...

Newly discovered antibody may be body's natural defense against Alzheimer's

...n, oligomers have been implicated as potent toxins responsible for Alzheimer's-linked memory loss and brain cell death. This has led many scientists to speculate that oligomers may be the main culprit in Alzheimer's and therefore a prime target for a new generation of disease-modifying treatments. To further...

Researchers shed light on mechanism of action used by anti-cancer drug

...ncers, including leukemia. Oncogenes are typically responsible for promoting tumor growth. Previous findings by Grant’s team, reported in the Journal of Biologic Chemistry, showed that in human leukemia cells, sorafenib lethality was less a consequence of Raf inhibition, but rather reflected interference with...

Herpes virus hijacks DNA repair process

...l fellow. "However, by targeting the viral protein responsible for activating the DNA damage response, we may be able to block viral replication. In addition, determining how the DNA repair response helps viral replication may enable us to develop novel strategies to treat infection." The paper appears online...

Research finds that circadian rhythms dominate all life functions

...e essential components of leptin signaling system, responsible for the sensation of satiety after eating. The osc...that typically oscillate together -- such as genes responsible for the function of an organ or a specific tissue -- are chaotic under this state and don't function...

Gene responsible for common hearing loss identified for first time

A gene responsible for the single most common cause of hearing loss among white adults, otosclerosis, has been identified for the first time, a scientist told the annual conference of the European Society of Human Genetics in Nice, France. Ms Melissa Thys, from the Dep...

Mutating the entire genome

...down like a dimmer switch. Other DNA sequences are responsible for folding and packing DNA into the nucleus of each cell. Five percent to 50 percent of DNA is considered useless junk, “depending on who you ask, although probably at least half of the ‘junk’ DNA is going to end up having a pretty important fun...

Potato wart eyed as risk to potato production

...amiliar with potato late blight, the plant disease responsible for widespread potato shortages, the lesser known potato wart has the potential to be as devastating to economies that depend on potato production, say plant pathologists with The American Phytopathological Society (APS). According to Gary Franc, p...

Weizmann Institute scientists develop a general 'control switch' for protein activity

... substance that increases the activity of proteins responsible for ripening. Moreover, numerous proteins are used in industrial processes, as biological sensors and in other applications. The possibility of controlling these applications – strengthening or slowing the rate of protein activity in an immediate and...

Children of smokers have more than 5 times higher levels of a nicotine toxin

...exposed to tobacco smoke at home, and smoke may be responsible for up to 6,000 deaths per year in young children. The authors say: ‘Babies and children are routinely exposed to cigarette smoking by their carers in their homes, without the legislative protection available to adults in public places.’ But ...

Researchers develop buckyballs to fight allergy

...cells from releasing histamine. Mast cells are responsible for causing allergic response and are packed with granules containing histamine. They are present in nearly all tissues except blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are rapi...

Ancient retrovirus sheds light on modern pandemic

...ion years ago ironically may be at least partially responsible for the susceptibility of humans to HIV infection today. These findings, reported by a team of researchers at Fred Hutchinson Cancer Research Center in the June 22 issue of Science, provide a better understanding of this modern pandemic infection th...

Putting feelings into words produces therapeutic effects in the brain

... be part of what the right ventrolateral region is responsible for,” Lieberman said. If a friend or loved one is sad or angry, getting the person to talk or write may have benefits beyond whatever actual insights are gained. These effects are likely to be modest, however, Lieberman said. “We typically thin...

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