Botox could help target resistant tumors for treatment
...ays, for vascular and perfusion changes as well as responses to anti-cancer therapies. In tests on oxygenation, cellular oxygen pressure was shown to significantly increase after treatment by Botox in both types of tumors. In tests on perfusion, magnetic resonance imaging results (MRI) showed significantly gr...Viral protein helps infected T cells stick to uninfected cells
... lymphocytes. These immune cells coordinate immune responses in part through physical contact with other immune cells. The cells adhere to one another using a protein known as LFA-1, which is found on the cells' surface. In this study, Lairmore and his collaborators examined the influence of the p12 protein ...Aspirin reduces cardiovascular risks in men and women -- but differently
...etter understand any differences in cardiovascular responses to aspirin." Specifically, among the 51,342 women in the analysis, there were 625 strokes and 469 heart attacks. Among the 44,114 men, there were 597 strokes and 1,023 heart attacks. However, the routine use of aspirin does not come without potenti...How taste response is hard-wired into the brain
...rychnine would seem to demand that such behavioral responses be so innate as to be hard-wired into the brain. I...erated taste behaviors. To directly monitor taste responses of the flies, the researchers generated flies with fluorescent labels on their neurons that would si...'Nano-keys' bind cell receptors and trigger allergic reactions
...ceptors on cell membranes and trigger larger-scale responses within cells -- such as the release of histamines ...nderstand the role of cell membranes in activating responses within cells. Barbara Baird, Cornell professor of chemistry and chemical biology, reported this res...Stanford study of owls finds link in brain between sight and sound
...wls, and then studied how that affected the neural responses in regions of the brain that process auditory info...ain that process visual information increase their responses to objects that the monkey is about to look at and decrease their responses to all other objects in ...Defective immune system response to smallpox vaccine detailed in new study
...natum and improves our understanding of the immune responses to smallpox vaccine of people with atopic dermatit...uction in atopic dermatitis skin. Comparing immune responses of skin cells grown in the lab from healthy volunteers and from people with atopic dermatitis, the r...Sweet 'water taste' paradoxically predicts sweet taste inhibitors
...e receptor. Findings revealed that the cellular responses directly parallel the human perceptual responses. ...of saccharin and acesulfame-K inhibit the cellular responses to other sweeteners by binding to a second, low-affinity inhibitory site that causes the receptor to...The Amazon in 2050: Implementing the law could save a million square kilometers of rainforest
... futures for this region. A study of deforestation responses to different policies will be published in the March 23, 2006, issue of Nature. It shows that simply implementing existing laws and proposed protected areas would spare the Amazon one million square kilometers of deforestation (one fifth of the enti...New nano-canary in the nanotoxicology coalmine: The body itself
...and, Wash., have harnessed living cells to monitor responses to a variety of biologically active test agents. They presented their findings Friday at the American Association for the Advancement of Science annual meeting. "Our process requires that live cells be grown on an infrared transparent substrate giv...Immune system response to viral DNA is unique
...way will shed light on the mechanisms of antiviral responses and how cells discern viral and self-DNA." ...Boosting newborns' immune responses
...ll-like receptors are stimulated, newborns' immune responses are very impaired," Levy says. "But there was one ...hat stimulate TLR8 could be used to enhance immune responses in newborns, perhaps as adjuvants given along with vaccines," Levy says. "We plan to test this appro...Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
...d produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 ...s used in the vaccine. "The high rates of immune responses at all dose levels in this initial human Ebola vaccine study support continued development of this v...BiovaxID?yields 89 percent survival in patients with aggressive non-Hodgkins
..., BiovaxID did induce anti-tumor T-cell lymphocyte responses in most patients. Depletion of normal B-cell lymph...lation; and T-cell lymphocytes, which mediate cell responses to immune stimulation ("cellular" immunity). B-cell lymphocytes can undergo malignant transformation...Picking apart how neurons learn
... automobile. "We've long known that LTD underlies responses like the vestibulo-ocular reflex. This study gets at the heart of how LTD occurs, specifically how PICK1 controls the Purkinje cell's response to the signaling molecule, glutamate," says Richard L. Huganir, Ph.D., a Howard Hughes Medical Institute in...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...hite blood cell types known to be involved in host responses to infection, and concluded by revealing a new an... that we have much yet to learn about human immune responses to infections. They also emphasize the importance of vitamin D in human immune responses, and sugge...H5N1 avian flu virus vaccine induces immune responses in healthy adults
...tal H5N1 avian influenza vaccine can induce immune responses in healthy adults. Approximately half of those v..., M.D. "For example, potentially protective immune responses were seen most frequently at the highest dose of this vaccine. We are investigating other options th...Simple idea to dramatically improve dengue vaccinations
...ld allow the body to simultaneously develop immune responses against all four versions of Dengue. "The literature about immunodominance is new and growing," Deem said. "Ours is the first model that can predict immunodominance, and when we compare our results with experimental data from Dengue vaccination tria...Frog’s ear canal may provide insights for understanding human hearing loss
...onents and ultrasonic components, and observed the responses of eight A. tormotus males to each of the split so...ed in sound processing and found marked electrical responses to sounds extending into the ultrasonic range -- both in the averaged response of a population of ne......d contribute to ongoing efforts to engineer immune responses in vaccine design and tumor immunotherapy and to a better understanding of the immune response against skin pathogens." "Now that we know which cells are the precursors to Langerhans cells and the importance of Csf-1, we may be able to enhance tumor...