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Tag: "response" at biology news

U of T researchers map role of Epstein-Barr virus in cancer

...3 protein. "Normally, p53 levels will increase in response to certain problems in the cell such as damaged DNA and this stops the cell from proliferating. Through binding USP7, EBNA1 keeps the p53 levels low so cells will continue to divide when they shouldn't, which means they're now more likely to develop ...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...by acting as a scaffold for signaling molecules in response to dopamine receptor activation," Caron said. "The observations also provide an alternative pathway by which dopamine receptor activation leads to the expression of dopamine-associated behaviors." The findings reveal another mechanism that could be...

Brain Scan Study of Smokers Reveals Signature of Craving

... smokers have found increases in brain activity in response to smoking-related images in areas associated with attention, motivation and reward. However, those studies examined smokers only after a period of overnight deprivation from smoking. To further explore this phenomenon, the researchers examined smok...

UN: World in big ecological mess

...s, with private sector and civil society input, in response to Mr. Annan's call for global support of the Millennium Development Goals (MDGs), which seek to slash a host of socio-economic ills such as extreme poverty and hunger by 2015. "The overriding conclusion of this assessment is that it lies within the...

Studies reveal how plague disables immune system, and how to exploit the process to make a vaccine

...liminating the elements that suppressed the immune response but retaining enough of the normal protein's structure to generate protective antibodies. Out of 11 altered versions they found one that met both criteria. In mouse and human macrophages, version rV10, missing amino acids 271 through 300, triggered ...

Immune system's distress signal tells bacteria when to strike back

...es ?the chemical messengers that trigger an immune response ?in the bowel. "These could signal the bug," said Alverdy, "then the bug strikes back and then the inflammation process snowballs." Because the bacteria in this case are "normal flora," people with no real infection develop a chronic disease. The ba...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...an proteins, they do not induce an unwanted immune response like products created from non-human sources often do." On behalf of Shen and his collaborators, USC holds the patent to the new recombinant fusion protein technology. The research was supported by grants from the National Institutes of Health. ...

Study: Well-known protein helps stem cells become secretory cells

...xpression in the salivary gland: CrebA (Cyclic-AMP response element binding protein A) and Fkh (Fork head). CrebA is required for the expression of the secretory genes throughout development, while Fkh appears to be required only in later embryonic stages. The group has shown that Fkh is required to maintain...

UNC plant researchers discover proteins interact to form hair-trigger protection against invaders

...is that the system remains poised for an immediate response to bacteria and other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and H...

Depression gene may weaken mood-regulating circuit

...ility to put the brakes on a runaway amygdala fear response depends upon the degree of connectivity in this ci...upling in the circuit, a poorly regulated amygdala response and impaired emotional reactivity ?resulting in increased vulnerability to persistent bad moods and ...

Proteomics brings researchers closer to understanding microbes that produce acid mine drainage

... understand how organisms change their behavior in response to the presence of other organisms and when their physical and chemical environments are perturbed." Coauthors with Banfield, Hettich and Thelen are post-doctoral fellow Rachna J. Ram, graduate student Gene W. Tyson and researcher Brett J. Baker of ...

FDA approves more generic AIDS drugs

...is that the system remains poised for an immediate response to bacteria and other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and H...

Specialized immune-system B cells play double-barreled role

... thought to play a major role in the innate immune response -- the type of immunity that offers rapid, general...hich the immune system develops a long-term immune response to an invader after vaccination or infection. The researchers -- Karen Haas, Jonathan Poe, Douglas ...

New method shows it is possible to grow bone for grafts within a patient's body

...take advantage of the body's natural wound-healing response and create a special zone on the surface of a healthy bone in hopes that the body would respond by filling the space with new bone. The approach lived up to their highest expectations. Working with mature rabbits, a species with bones that are very s...

Poaching, logging, and outbreaks of Ebola threaten central African gorillas and chimpanzees

...uatorial Africa, the document seeks a multilateral response to the threats to populations of the western lowla... anti-poaching activities, improved monitoring and response to Ebola outbreaks, increased training, and tourism development. "As dire as the threats are to t...

Scientists reveal how disease bacterium survives inside immune system cell

...riments, the research team compared the neutrophil response to A. phagocytophilum with that of a weak strain o...nt human genes, the researchers discovered how the response to A. phagocytophilum deviates from that of S. aureus, and thus permits the HGA agent to survive. "...

A whole lot of shaking goin' on triggers early hatching in red-eyed tree frogs

...etermine whether the frog embryos were hatching in response to vibration and not to some chemical or visual cu...tches. Sure enough, the eggs hatched more often in response to snake-attack recordings than rainstorm recordings. "They hatch when the snake starts biting the ...

Arthritis: What Wnt wrong?

...ating the importance of Wnt-7b in the inflammatory response of RA. The above findings identify a role for Wnt...sites of inflammation and elicited an inflammatory response are consistent with inflammation as a hallmark of RA disease. Co-author Dr. Yukio Nakamura is an Or...

Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton

... however, an understanding of zooplankton swimming response to ocean currents has remained elusive, mainly due to the lack of technology to track the motions of the miniscule animals in the sea. Now, an international team of scientists from Israel, the United States and Germany led by Amatzia Genin of the He...

Blink, and the brain misses it

.... Bristow et al.: "Blinking suppresses the neural response to unchanging retinal stimulation." Publishing in Current Biology, Vol. 15, 1296?300, July 26, 2005. DOI 10.1016/j.cub.2005.06.025 www.current-biology.com ...

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