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Tag: "response" at biology news

Secret of smallpox's success may lead to bioterror cure

... post-exposure vaccine is to strengthen the immune response to the vaccinia virus by completely eliminating th...s is to the immune system, the stronger the immune response should be and the better the body should be able to fight off a smallpox infection. Over the past 1...

Gene therapy cures inherited liver disease in rats

...see one developed that minimizes the body's immune response to it immediately right after it is injected into the body. "Fifteen years ago, the goal was to get some correction of the problem," he said. "Most effects were transient. Now with these vectors, long-term correction with no long-term toxicity is po...

Brain May Be Less Plastic Than Hoped

...e adult primate brain displays less flexibility in response to retinal injury than previously thought, according to a new study published in the May 19, 2005, issue of the journal Nature. This may have implications for other regions of the brain, and the approach the investigators used may be a key to develop...

Master gene controls healing of skin in fruit flies and mammals

... that grainyhead-like factors are required for the response to injury opens up new avenues of research in the ...t the grainyhead gene initiates the cuticle repair response after it receives an as-of-yet unidentified signal produced in cells adjacent to the injury." In it...

Scripps scientists find potential for catastrophic shifts in Pacific ecosystems

..., random physical changes can provoke an amplified response in the biology in ways that may not be easily or symmetrically reversed. These measurements show that asymmetrical and even irreversible ecological change is possible." Irreversibility means that if the ecosystem changes dramatically due to, for exa...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...elates to different disease states and a patient's response to drug therapy," said Noel Doheny, Vice President of PreAnalytiX and QIAGEN. "We continue to see a strong market trend towards the correlation of gene expression profiles of whole blood and tissue samples. With the new GeneChip Globin-Reduction Prot...

Designing vaccines by computer

...been shown by experiments to effectively trigger a response by the immune system. They look for common patterns in their sequences or structures and use the information to create a theoretical model of what is needed for one of these fragments to trigger an immune response. They can then employ computers to s...

Python a 'hearty' eater

...rt occurs in adapting to prolonged exercise and in response to some diseases. The python does not eat frequently; it's more of a binge eater. James Hicks at the University of California, Irvine, together with his colleagues, discovered the snake's tell-tale heart undergoes drastic physiological changes after...

Mouse with designer liver has enhanced glucose tolerance, insulin response

...culating triglycerides in the bloodstream. Insulin response to glucose load was diminished in LGKO mice, thus ...oming in on enzymatic pathways critical to insulin response in cells. Upon stimulation with insulin, they found an elevated level of Akt/PkB kinase, an enzyme n...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...he conclusion that mutation is a programmed stress response -- a survival mechanism. If the cell senses damage, and if the damage persists beyond its ability to repair it, the cell will turn on its mutation machinery and open the floodgates for evolution. Take the bacterium Escherichia coli for instance. Whe...

Wake Forest scientists find new combination vaccine effective against plague

...?one method of vaccination ?produces little if any response in the mouse immune system. But if a protein termed flagellin is added to the vaccine, antibody levels against the plague bacteria are 500,000 times higher. "Flagellin can function as an effective adjuvant, making a vaccine that protects against the...

Radio-tracking associated with 'dramatic shift' in water vole sex ratio

...habitats, similar to the sex-ratio bias and stress response in food deprived water voles," they say. Researchers have long been aware that the techniques they use had the potential to cause unexpected effects, and there have been many studies into the effects of radio-collars. However, this is the first stud...

Future diabetes drugs may target new protein interaction

...now know that sirtuin1 is directly involved in the response to calorie restriction in mammals and in processes involved in cellular aging," says Puigserver. "But we still don't know whether sirtuin1's activity affects lifespan in mammals." There is a precarious anecdotal link, however. In 2003, other scienti...

'Smart drug' targets deadly brain cancer

...rme participating in this study -- which is a high response rate for this very resistant disease. These early results suggest that we are on to a promising new treatment strategy that could potentially help us improve treatment for patients with recurrent glioblastoma." Achieving the 36 percent regression ra...

PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

...now know that sirtuin1 is directly involved in the response to calorie restriction in mammals and in processes involved in cellular aging," says Puigserver. "But we still don't know whether sirtuin1's activity affects lifespan in mammals." There is a precarious anecdotal link, however. In 2003, other scienti...

Computational verification of protein-protein interactions by orthologous co-expression

...now know that sirtuin1 is directly involved in the response to calorie restriction in mammals and in processes involved in cellular aging," says Puigserver. "But we still don't know whether sirtuin1's activity affects lifespan in mammals." There is a precarious anecdotal link, however. In 2003, other scienti...

Eliminate Data Analysis Bottlenecks in Drug Discovery

...now know that sirtuin1 is directly involved in the response to calorie restriction in mammals and in processes involved in cellular aging," says Puigserver. "But we still don't know whether sirtuin1's activity affects lifespan in mammals." There is a precarious anecdotal link, however. In 2003, other scienti...

Researchers find gene that may be at root of potato blight

...tations in their Avr3a gene escaped the resistance response triggered by R3a. Further laboratory analysis showed that when R3a detected Avr3a in a leaf cell, that plant cell died. "This programmed cell death is how the plant keeps the pathogen from spreading to other cells," Kamoun said. "Only a few cells d...

WHO suspends Marburg work, appeals for new funds

...ited Nations, for funding to support the emergency response to this outbreak. WHO needs US$ 2.4 million to support the Ministry of Health, Angola to intensify ongoing operations in the field. To reduce the risk of transmission in the community, priority activities include intensive social mobilization and he...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

...determines the level of expression of early growth response (Egr) proteins, with cells choosing the gamma-delt...delta-gamma T cells seem to form the first line of response against external disease-causing agents, including bacterial infections, tissue damage and stress," ...

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