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Tag: "response" at biology news

Gene controlling circadian rhythms linked to drug addiction

...that, in mice, the Clock gene regulates the reward response to cocaine, suggesting that similar actions take place in humans. Findings from the multi-center study are available online in the Proceedings of the National Academy of Sciences. "We found that the Clock gene is not only involved in regulating slee...

Survival of heart patients on beta-blockers varies greatly with genetic variation

... genes influence such parameters as blood pressure response in hypertensive patients and heart function in heart failure patients. "But this is the first time that anyone has shown that these genetic variations affect survival," McLeod says. Humans have two types of beta-adrenergic receptors, beta-1 and be...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...iber measures the contractile force of the cell in response to that stretch. "It's like stretching a rubber b... mice had about 70 percent more passive tension in response to the stretch. Compared to normal myocytes, mdx myocytes were stiffer and resistant to stretching. ...

Physical and functional interaction of key cell growth molecules linked to cancer

...mained elusive. Recent studies have shown that in response to growth factor stimulation, a fraction of EGFR molecules move from the cell membrane into the nucleus, where the genetic material of the cell is located. These research studies suggest that EGFR itself probably does not directly regulate gene expre...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...xes' that humans do -- shifting their attention in response to the direction of gaze of another individual. Th...gaze. 'But to get a real understanding of how this response is accomplished at a neuronal level, you need an animal model that you can manipulate physiologicall...

New Lab Research May Help Those Deafened By Immune System Attack

... the ultra-sensitive hair cells, whose movement in response to vibrations creates the nerve signals that are f...ated the results of those two tests with patients' response to steroid treatment, based on standard criteria and the results of hearing tests performed before a...

Study identifies gene in mice that may control risk-taking behavior in humans

...ng the next time they hear the tone, a physiologic response that indicates they expected a shock. The mice rem...put them into a situation that would elicit a fear response in normal mice. They used a maze elevated 40 centimeters above a tabletop where mice had the option ...

Nose odors and mouth odors: The brain distinguishes

...d their exploration into the brain's possible dual response to odors because of the well-known phenomenon that sensing an odor "orthonasally" through the nose triggers the perception that it is coming from the outside world, while sensing it through the mouth--or "retronasally"--causes the perception that it ...

Treatments have same target, different responses for lung cancer patients with genetic mutation

...e drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux), according to a new study published in the August 17 issue of the Journal of the National Cancer Institute. Both drugs target the same gene but through different mechanisms. Some patients with non�small-cell lung c...

Discovery of T-cell 'traffic control' boosts new drug promise

... and on to tissues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own...e T cell surface that suppresses the cells' normal response to a "forward march" signal. T cells respond by chemotaxis -- moving from areas of lower to higher ...

Duke Experiments Boost Radiation's Cancer-Killing Effects

...opriate time, it substantially increases a tumor's response to radiation therapy." Specifically, they found t...atment -- can make all the difference in a tumor's response to that therapy, said Moeller. "Just as putting on a coat and gloves in the middle of summer would ...

IBM Transforms the Art of Scientific Expeditions

...opriate time, it substantially increases a tumor's response to radiation therapy." Specifically, they found t...atment -- can make all the difference in a tumor's response to that therapy, said Moeller. "Just as putting on a coat and gloves in the middle of summer would ...

Bird samples from Mongolia confirmed as H5N1 avian flu

.... The multidisciplinary, collaborative response to this latest outbreak reflects the WCS One World-One Health approach to making informed, multidisciplinary decisions on global health crises that intersect human, wildlife, and livestock health. WCS experts are warning that to contain this potentia...

Past droughts geographically widespread in the West, according to tree-ring data

...ona is the one of many initiatives taken by SRP in response to an ongoing drought that is in its 10th year. Even counting this past winter when 2,017,580 acre-feet of runoff ?the first above-normal runoff season since 1998 -- filled the reservoirs on the Salt and Verde rivers, stream flows into the Salt and V...

Rodent social behavior encoded in junk DNA

...enced by the hormone," added Hammock. "An animal's response to vasopressin thus depends upon which rooms have the locks and our research shows that the distribution of the receptors is determined by the length of the microsatellites." Prairie voles with the long version have more receptors in circuits for so...

How cell suicide protects plants from infection

... identified a gene that regulates the major immune response in plants, programmed cell death (PCD), according to a recent report in the journal Cell. To protect themselves from viruses, plants create a zone of dead cells around an infection site that prevents the infection from spreading. Savithramma Dinesh-...

New imaging technology shown to detect pancreatic inflammation in type 1 diabetes

... diabetes, but most of all for early prediction of response to therapy, which might be very useful for reducing the time and cost of clinical trials. "Because the results in mice looked so good, and because our MGH colleagues have already successfully used essentially the same drug on many patients with prost...

York scientists warn of dramatic impact of climate change on Africa

...c changes may soon occur in Africa's vegetation in response to global warming. They believe the effect may be...ean, of York's Environment Department to study the response of plants to climate change. Dr Lovett added: "We needed a method that would help fill in gaps in k...

Why do aneurysms form? New studies suggest leading role for white blood cells

...ding that in general, an aneurysm is an inadequate response to injury," Upchurch explains. "Something happens ...or some reason, the immune system's normal healing response doesn't work. Something eats away at smooth muscle cells in the wall of the aorta until it starts to...

Women cautioned against using herbal supplements

...ct was found to have no effect, while a beneficial response from chaste tree berry extracts was found in about half the women studied. For menstrual pain, two clinical trials have examined the Japanese herbal preparations toki-shakuyakusan and toki-shakuyakusan with shakuyaku-kanzoto; neither found a benefici...

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