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Tag: "resisting" at biology news

A simple feedback resistor switch keeps latent HIV from awakening

...at must rapidly alternate between two states while resisting noise in the environment. Their model may also provide an explanation for some puzzling observations about Tat and HIV. Tat contains at least two acetylation sites that must both be deacetylated to turn off transcription. The authors propose this req...

Newly identified mechanism helps explain why people of African descent are more vulnerable to TB

... used by human macrophages that may be critical to resisting infection with certain pathogens and that turns out to be critically dependent on vitamin D. This description provides a different way to think about how human immune systems battle pathogens in general. The research team found that when Toll-like ...

Infant transplant patients resist infections that kill adult AIDS patients

...In fact, the post-transplant patients do very well resisting infections. It seemed to us very important to understand why this is so, because maybe that would help us help people with age-related diseases caused by declining immunity, or AIDS, or cancers, and understand why certain people tend to be more susce...

Plant defenses prompt bacterial countermeasure in the form of 'island' DNA excision

...vated by humans ?plants have developed systems for resisting the attack of microbial pathogens, while these microbes themselves have depended on their ability to alter molecular attack strategies in order to flourish. In the new work, researchers have essentially caught one step of this arms race in action, an...

FDA approves more generic AIDS drugs

...other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and HSP90 keep resistance proteins ready to perceive pathogen signals, and SGT1 pr...

UNC plant researchers discover proteins interact to form hair-trigger protection against invaders

...other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emerging story is that RAR1 and HSP90 keep resistance proteins ready to perceive pathogen signals, and SGT1 pr...

Breakthrough System for Understanding Ocean Plant Life Announced

...c strategy for evading the human immune system and resisting treatment, the current treatment for this disease is melarsopal, an antiquated drug with terrible side effects, including death. In the February issue (Volume 17, Issue 3) of the journal Molecular Cell, scientists in the Marine Biological Laboratory...

Newly discovered protein an important tool for sleeping sickness research

...c strategy for evading the human immune system and resisting treatment, the current treatment for this disease is melarsopal, an antiquated drug with terrible side effects, including death. In the February issue (Volume 17, Issue 3) of the journal Molecular Cell, scientists in the Marine Biological Laboratory...

NHGRI targets 12 more organisms for genome sequencing

...s species is exceptionally able at adapting to and resisting many pesticides. Understanding this resistance at a molecular level can lead to safer and more effective pesticides and improve human nutrition. The genome of the pea aphid, used extensively as an experimental model, will be a valuable comparison wit...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

...-delta T cells. Despite their clear importance in resisting disease, the processes controlling the generation of gamma-delta T cells have remained mysterious until recently. As Robert Frost put it, Wiest pointed out: "Two roads diverged in a wood, and I-- I took the one less traveled by, And that has made all...

Defenseless plants arm themselves with metals

...ver really made sense to me. If everyone's already resisting pathogens, why do you need an extra mechanism? There has to be more to it." It turns out the plants Salt studies - a group of small, weedy alpine flowers called Thlaspi - lack the standard pathogen defense mechanism found in nearly every other plant...

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