Environmental metagenomics diagnosing extreme environments, tapping opportunities for clean energy
...hallenge is that the vast majority of microbes are resistant to being grown under standard laboratory conditions. Through the emerging strategy of metagenomics--isolating, sequencing, and interpreting the DNA extracted directly from the environment in question, an informative window opens onto that important a...Driver of anthrax toxicity could lead to late-stage therapy
...-called LDL receptor-related protein (LRP6) become resistant to anthrax toxin. Furthermore, antibodies against LRP6 protected cells from anthrax toxicity, reported study authors Wensheng Wei and Stanley Cohen of the Stanford University School of Medicine in collaboration with others at Stanford and the Nationa...Researchers create pigs that produce heart-healthy omega-3 fatty acids
...ays. Adapting to and surviving chemotherapy, these resistant cells could breed, leading to a cancer relapse. He hopes to pursue this hypothesis in the future. "More immediately," he adds, "we intend to validate the new study with other cohorts and other types of tumors." ...Evolutionary biology research techniques predict cancer
...ays. Adapting to and surviving chemotherapy, these resistant cells could breed, leading to a cancer relapse. He hopes to pursue this hypothesis in the future. "More immediately," he adds, "we intend to validate the new study with other cohorts and other types of tumors." ...York researchers develop pollution-busting plants to clean up contaminated land
...in pollution of land and groundwater by explosives resistant to biological degradation. Large tracts of land used for military training, particularly in the USA, are contaminated by RDX, one of the most widely-used explosives, which is both highly toxic and carcinogenic. The six-strong CNAP team has isolated...Microbes convert 'Styrofoam? into biodegradable plastic
...her disposable items. The biodegradable plastic is resistant to hot liquids, greases and oils, and can have a long shelf life. But unlike polystyrene, it readily breaks down in soil, water, septic systems and backyard composts. Worldwide, more than 14 million metric tons of polystyrene are produced annually, ...New evidence questions the simple link between prion proteins and madcow disease
...ow this resistance is achieved. One option is that resistant people do not absorb the disease-associated prion ...eing due to an invisible sub-fraction of digestion resistant PrP molecules is unlikely. The possibility of there being infectious molecules other than PrP must t...Plants give pests sock in the gut
...versity have since developed several lines of corn resistant to multiple pests, using conventional plant breedi...s with plants susceptible to the insects and those resistant to them. Results indicate that after seven days, the level of both IIM and IIM messenger RNA in inse...MRSA use amoeba to spread, new research shows
...oeba first, MRSA may emerge more virulent and more resistant to antibiotics when it infects humans. "Infection...ts that pathogens that emerge from amoeba are more resistant to antibiotics and more virulent. "This makes matters even more worrying," said Professor Brown. ...Poison + water = hydrogen. New microbial genome shows how
...x to be used as a bioweopon because the spores are resistant to heat, radiation, and other treatments. By comparing this genome to those of other spore-making species, including the anthrax pathogen, Eisen and colleagues identified what may be the minimal biochemical machinery necessary for any microbe to s...Researchers uncover mechanisms of estrogen in promoting cell death in breast cancer
... of breast cancer cells, called MCF-7:5C, that are resistant to estrogen withdrawal and that undergo apoptosis when treated with very small concentrations of estradiol. The researchers treated MCF-7:5C cells with estradiol and fulvestrant, and they also injected the cancer cells into mice to study estradiol's ...'Good' bacteria could save patients from infection infection by deadlier ones
... especially involving the deadly MRSA (methacillin resistant staphylococcus aureus) bacteria. Despite being around for 40 years, these bacteria are still basically found only in hospitals. The question Spigelman asks is why? Spigelman, who is also a visiting professor at University College London, argues in ...GROWing the next generation of water recycling plants
...rigold, and the common reed. They are chosen to be resistant to the pollutants they absorb. By planting more than one species, the engineers guard against an unusually dirty batch of water exceeding a particular species' tolerance level. Should one species die off, there will still be others there to continue ...Scientists show how thinking can harm brain cells
...ervous system to experience stress and become more resistant to future encounters with stress and the damage it can trigger," said Harris A. Gelbard, M.D., professor of Neurology at the University of Rochester Medical Center and the research project's principal investigator. A long-standing villain in neurod...Anyway you slice it, tomatoes cut through drought with new gene
...VP1 in Arabidopsis to create hardier, more drought resistant plants were published in the journal Science in October, but the study described in the proceedings marks the first time the enhanced gene has been inserted in a commercially viable crop, he said. The paper notes that drought conditions througho...Lateral thinking produces first map of gene transmission
...ws how disease-causing bacteria can quickly become resistant to treatment: a bacterium with genes that confer drug resistance can, through lateral transfer, rapidly spread them to other bacteria, instead of just to their own offspring. From the early days of the science of genetics, it was assumed that trans...Switching to new anti-bacterial targets: Riboswitches
... and fungi fail to grow in pyrithiamine and become resistant by acquiring mutations in their riboswitches. This...lifetime of a drug and makes it possible to tackle resistant 'superbugs' with combinations of drugs. The analog, pyrithiamine, was synthesized decades ago to s...Finding rewrites the evolutionary history of the origin of potatoes
...ant trait - for example, that a certain species is resistant to disease - then everything related to that species becomes potentially useful," Spooner says. "We can screen samples to see if related germplasm has similar resistance, in which case we may be able to guide plant breeders to germplasm to use in br...Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection
...nts the first demonstration that cells can be made resistant to HIV infection by treatment with Sangamo's propr...The researchers found that ZFN-modified cells were resistant to HIV infection whereas control cells were infected when challenged with the virus. Furthermore, w...Evolutionary conservation of a mechanism of longevity from worms to mammals
...- embryonic stem (ES) cells and show that they are resistant to oxidative stress and exhibit reduced DNA damage when compared to ES cells in which this gene is active. Because these findings would predict that reduced expression of the mclk1 gene would result in longevity, the authors compared the lifespan ...