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Tag: "resistant" at biology news

For the first time: Longevity modulated without disrupting life-sustaining function

...riately to oxidative stress, but they are just as resistant to heat stress as wild type worms whose signaling pathways have not been experimentally manipulated," explained Wolff. "In the future, we may use this protein as a tool to study the genetic and metabolic requirements for extending longevity without...

Genetic mutation linked to West Nile virus infection

...o copies of this mutation (CCR5delta32) are highly resistant to HIV infection, even when repeatedly exposed to the virus. This resistance was the theoretical basis for the development of therapeutic CCR5 inhibitors, several of which are now in clinical trials, for the treatment of patients with HIV. CCR5 see...

Major WHO study concludes calcium supplements can reduce complications during pregnancy

...y in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, p... a diverse array of HIV mutants, some of which are resistant to antiviral drugs. Drug-resistant strains of HIV are being found more often in recently infected pe...

Computer simulation hints at new HIV drug target

...y in the United States harbor HIV viruses that are resistant to at least one of the available drugs. In fact, p... a diverse array of HIV mutants, some of which are resistant to antiviral drugs. Drug-resistant strains of HIV are being found more often in recently infected pe...

Viral 'fitness' explains different resistance patterns to aids drugs

...taking by patients causes HIV to mutate and become resistant to the effects of the medications, while the medic...tions that were consumed, in turn, cause the newly resistant virus to become less fit. The type of medication also factors in. Differences in viral fitness of m...

Plant-derived vaccines safeguard against deadly plague

...to bioterrorism. "There have been discovered some resistant strains to antibiotics and that poses a concern, especially if plague would be used as a bioweapon," said Luca Santi, a research assistant professor at the institute and lead author of the study published in the early online edition of the journal Pr...

Losing sleep undoes the rejuvenating effects new learning has on the brain

..."implies that some kinds of cognitive function are resistant to sleep loss," Hairston said. "This may be significant in human learning as well, and implies that it may be possible to optimize the way information is presented to rested versus fatigued individuals to take advantage of the specific neural substra...

Scientists re-engineer a well-known antibiotic to counter drug resistance

...the most common strains of enterococci have become resistant to vancomycin and use of the antibiotic has been u...inst VanA, a strain of the bacteria that is highly resistant to treatment by glycopeptide antibiotics, including vancomycin and teicoplanin (a somewhat newer dru...

Supersized 'island' of resistance genes discovered in an infectious bacterium

...mber of laboratories already working on multi-drug resistant A. baumannii throughout the world. This is a demo...ompletely susceptible to antibiotics and now it is resistant to a wide-range of antibiotics. "A. baumannii is exceptionally prone to pick up foreign DNA from ot...

Less antibiotic use in food animals leads to less drug resistance in people, study shows

...f the locally acquired Campylobacter isolates were resistant to ciprofloxacin, a type of fluoroquinolone. Countries that allow fluoroquinolone use in animals may have a drug resistance prevalence of up to 29 percent. Ciprofloxacin can be used to treat severe Campylobacter disease, so a low level of bacterial d...

Predicting chemotherapy outcome

...ell to combined chemotherapy and patients who were resistant to the therapy. These findings could be used in cl...ll to chemotherapy compared with patients who were resistant to the therapy. The results were validated by RT-PCR analysis, which confirmed the differential expr...

Salmonella caught red-handed

Pathogens are becoming increasingly resistant to antibiotics, causing problems for therapy. Doctors need to have antibiotics available that work in new kinds of ways. The last few years of research have, however, found few such ways. One major difficulty for developers of antibiotics is choosing...

Botox could help target resistant tumors for treatment

...owing for more effective destruction of previously resistant cancer cells. The study is the first to test the idea of using Botox against cancer and explores the possibility of its use as an adjuvant, assisting the effective delivery of chemotherapies and radiation. The findings mark a relatively new area of ...

New cellular flaw found in some virulent breast cancers

...gineered to lack cyclin D1 were found to be highly resistant to certain breast cancers, and other experiments s...CDK4 kinase were developmentally normal and highly resistant to ErbB-2-caused breast cancers, demonstrating that blocking CDK4 was not harmful to the mice. That ...

Newly discovered protein kills anthrax bacteria by exploding their cell walls

...ant of anthrax spores." Because anthrax spores are resistant to most of the chemicals that emergency workers re...it is so specific, the chances of anthrax becoming resistant to PlyPH, as it is to many of the antibiotics currently available to treat it, are extremely low. "...

Virginia Tech helping to develop higher quality, disease-resistant wheat varieties

...lect varieties possessing genes conferring durable resistant to powdery mildew, which causes annual crop loss of 10 to 30 percent in the Mid-Atlantic region. Researchers also will be identifying genes that confer superior milling and baking qualities. The new technology implemented in this project is called M...

Lack of a key enzyme dramatically increases resistance to sepsis

...w study showed that caspase-12 deficient mice were resistant to peritonitis and septic shock and were able to clear pathogenic bacteria more efficiently than mice with the enzyme. The presence of caspase-12 also reduced production of several pro-inflammatory cytokines, increasing vulnerability to bacterial inf...

Researchers use dirt to stay one step ahead of antibiotic resistance

...at the numerous ways soil-dwelling bacteria become resistant to antibiotics are identical to the resistance pat...g level of resistance. Not only were the bacteria resistant to an average of seven to eight antibiotics, but every strain was found to be multi-drug resistant. ...

Experimental TB drug effective against resistant and latent mycobacterium tuberculosis

...isms, which merely enhances the emergence of drug- resistant strains. No resistance has been encountered to FAS20013 in clinical isolates,. The short-term killing power of FAS20013 is greater than currently used drugs; for example, FAS20013 will kill more organisms in a 4-hour exposure than isoniazid or rifamp...

Successful cell engineering may lead to mad cow prevention, say researchers

... been silenced have demonstrated the animals to be resistant to prion-mediated diseases such as BSE. Their wor...er genes that could be targeted to produce animals resistant to a variety of diseases. Moreover, the success raises possibilities to develop similar disease res...

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