resistant 2 7

Tag: "resistant" at biology news

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

...helps them live long, spread to new sites and grow resistant to chemotherapy. Narayan's team has previously studied cells that were exposed to the chemicals found in cigarette smoke yet did not die. In general, about two-thirds of these cells will be growth-retarded, and some actually acquire cancer-like cha...

Mouse mimics chronic leukemia, will aid drug development

...he drug fludarabine, but the disease often becomes resistant to the drug. This TCL-1 mouse strain was originally developed by OSU cancer researcher Carlo M. Croce, professor and chair, department of molecular virology, immunology and medical genetics and director of human cancer genetics at the OSUCCC-James...

Mass. General study finds potential ovarian cancer stem cells

...e. "We feel these stem-like cancer cells may be resistant to traditional chemotherapy and could be responsib...or would be able to recur quickly, often in a form resistant to chemotherapy. Similar cancer stem cells have been previously identified in leukemia and breast c...

Innocuous intestinal bacteria may be reservoir for resistance

...between antibiotic use and isolation of multi-drug resistant Salmonella. Where does the drug resistance in Sal...otic-resistance genes as those found in multi-drug resistant Salmonella strains found on the same farm. In addition, isolation of antibiotic-resistant Salmonell...

Purdue creates new low-cost system to detect bacteria

...ight be used to identify staph infections that are resistant to antibiotics. "This is an extremely dangerous infection, and you want to catch it as early as possible," Robinson said. A mass-produced system based on the technology would consist of inexpensive, off-the-shelf hardware, such as red lasers and ...

Technique speeds up detecting, treating wound bacteria

...cteria that cause hospital-acquired infections are resistant to at least one of the drugs most commonly used to treat them. So far Finegold and his colleagues have been able use real-time PCR to detect 20 of the most common bacteria found in wounds, including one, Finegoldia magna, which had been named after...

Honey helps problem wounds

... hospitals today we are faced with germs which are resistant to almost all the current anti-biotics,' Dr. Arne Simon explains. 'As a result, the medical use of honey is becoming attractive again for the treatment of wounds.' Dr. Simon works on the cancer ward of the Bonn University Children's Clinic. As far a...

New protein target may advance design of HIV and cancer drugs

... viruses with drugs, over time patients can become resistant to treatment and the drug becomes ineffective. Therefore, novel biological processes and proteins are attractive targets for antiviral drug development," said lead author Nicholas Farrell, Ph.D., professor and chair in the Department of Chemistry at ...

Researchers find molecular 'brake' to cell death

...poptosis," Tang says. Cancers that quickly become resistant to therapy, such as melanoma and ovarian tumors, do so because they have found ways to prevent mitochondria from releasing a lot of CC, he says. Tumor cells also don't want to decrease their nucleotide pool, because they need ATP for continued functi...

Mutation in blood stem cells provides clues to cancer development

...due to a reservoir of leukemic stem cells that are resistant to current therapies. The discovery of the JAK2 mutation in stem cells in patients with PV is an important first step in developing treatments which target the earliest population of cells which propagate the disease." The research also provides mo...

A step forward in the fight against bacterial infections

...fatal. Because more and more bacteria are becoming resistant to the pre-eminent remedy; antibiotics; the search...combination of important characteristics: they are resistant to LPS, but they still recognize and destroy pathogens. The limited quantity of type 1 interferons e...

Gene thwarts some pathogens, gives access to others, could save crops

...empting to invade. "This gene, BIK1, makes plants resistant to pathogens such as Botrytis, but it allows biotr...uding Botrytis. But unexpectedly, it is completely resistant to virulent strains of the biotrophic bacteria." The study of BIK1's role in plant resistance to th...

History of human cannibalism eats away at researchers

...on polymorphism in the PRNP gene were relatively resistant to the disease. Over time, homozygotes who participated in the cannibalistic rituals purportedly diminished in numbers due to their increased susceptibility to kuru. This indicated that cannibalism conferred an effect of balancing selection on the...

Molecular force field helps cancer cells defend against attack

...UF's College of Medicine. "It also makes them more resistant to our attempts to kill them. And we're trying to understand exactly why this gene, which is a small enzyme molecule, is very intimately associated with tumor cell survival." Focal adhesion kinase, or FAK, is commanding increasing attention and has ...

Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections

Staph infections resistant to antibiotics, previously only associated with ho...Medicine, reports on a dramatic rise in antibiotic resistant community-acquired methicillin-resistant Staphylococcus aureus (MRSA), making it the primary cause o...

A large step forward in the fight against African sleeping sickness

...: Trypanosoma brucei rhodesiense. This parasite is resistant to ApoL-1, because it has particular proteins that counteract ApoL-1's action. For some time now, scientists have known that a variant of ApoL-1 is not neutralized by Trypanosoma brucei rhodesiense. This truncated ApoL-1 variant can help to overcome...

Faults in newly discovered breast stem cells may lead to tumours

...er cells. But an errant stem-like cell may be more resistant to chemotherapy because it divides more slowly. So while chemotherapy can eliminate the bulk of cancer cells, the tumour factory itself ?a breast cancer stem cell ?may survive months or years later. In the context of international breast cancer res...

UCLA paper examines how one disease may prevent another

...nic diet is still used today for cases of epilepsy resistant to medication. During the 1994 winter of starvation when bread supplies to the children's hospital were interrupted at The Hague, young patients with celiac disease, a digestive disease that damages the small intestine and interferes with absorptio...

Drug-resistant bacteria patterns in intensive care units changing nationally

...alence, there was also a decrease in MRSA that was resistant to multiple drugs. The researchers hypothesize that the influx of MRSA strains from the community might have replaced those multidrug-resistant strains associated with the hospital. "Unlike traditional MRSA the community strain is very fit - it ca...

Genetically engineered mosquitoes show resistance to dengue fever virus

...yos, creating the first stable transgenic mosquito resistant to Type 2 dengue fever virus, the most prevalent s...ability of the dengue virus to make the mosquitoes resistant to infection. This vulnerability occurs when the virus replicates and its single strand of RNA -- a ...

1 2 3 4 5 6 7 8 9 10