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Tag: "resistant" at biology news

Important gene controlling tree growth and development found

.... The tree is now dormant and is as such much more resistant to drought and frost than if it had been actively growing. It has been known for a long time that the trees sense that fall is coming by measuring the length of the day. When the days get shorter the trees "know" that it is time to stop growing and ...

New study reveals structure of E. coli multidrug transporter protein

...out selecting specific drugs to expel." Multidrug resistant bacterial infections raise the cost of medical tre...some general structural features across multi-drug resistant transporter families." Other authors of the study include Yong Yin, Xiao He, Paul Szewczyk, and Tha...

Scientists discover new regulating mechanism in cells

...drugs target the virus itself, which often becomes resistant to them, rendering the drugs ineffective. Antiretroviral drugs that affect cellular targets might be less prone to resistance.) "Retroviruses seem to take advantage of RHA to enhance production of their own proteins, and cells use it to control the...

More than drought affecting wheat yields

...We're trying to develop some cultivars that can be resistant to wheat streak mosaic and could be planted early and then grazed out," Rush said."They would be popular in this region and serve an important purpose." The problem now, he said, is any resistance breaks down in high temperatures. And not enough ...

Increased sensitivity to nerve signals keeps diabetes at bay

...e researchers found. Moreover, such animals become resistant to developing symptoms of diabetes or prediabetes when fed a high-fat diet. The findings suggest that drugs that boost the activity of the M3 receptors on pancreatic beta cells might have therapeutic potential, said Jurgen Wess of the National Insti...

Trials for new drug to overcome HIV

...own that the drug defeats strains of HIV which are resistant to other anti-HIV drugs. A small human trial of the drug, reported last August, showed that when given on its own it rapidly clears most HIV from the blood, driving down the levels tenfold in a matter of hours. The trial planned for this month is in...

Potato blight pathogenicity explained by genome plasticity

...cations. "The efforts of plant breeders to obtain resistant varieties by introducing R genes, either by classical breeding or by genetic modification, may be a waste of time and resources when the genome dynamics of the pathogen population is not understood," says Govers. "Monitoring field populations of p...

Study provides new understanding of spontaneous hybridization

...ng two parent species. Not only were these hybrids resistant to the insects that attack sunflowers, they also produced more seeds than the uncrossed plants. "The results show for the first time that adaptive trait introgression can be a potent evolutionary force, broadening our view of the mechanisms by whic...

New treatment for food poisoning

...hen tested this way, Listeria had been shown to be resistant to the antibiotic, fosfomycin. As a consequence, this drug has never been considered for the treatment of listeriosis. Dr Mariela Scortti, lead author on the paper, added: "Our findings warn about the need to revise laboratory methods currently in u...

Discovery could aid fight against cystic fibrosis infection

...nts' death. PA is difficult to treat because it is resistant to many drugs. "Since we know so little about what this bacterium is up to while it's engaged in these chronic infections, the discovery of this protein secretion system might lead to finding a new target for treatments," said Mougous, a research ...

New bird flu drug promises to beat the problem of resistance

.... "By the time the influenza virus becomes fully resistant to the drugs currently in use, we should have this as a viable alternative." Dr McKimm-Breschkin is also very optimistic about the new project. "We are aiming to produce a likely drug candidate within the three year period," she said. "Howeve...

Research links protein to breast-cancer migration

...rugs that can kill invasive cells that have become resistant to standard treatment." A further £143,000 has been awarded by the charity to Dr Keith Brennan, again in Life Sciences, to uncover how a group of proteins called Notch are able to protect breast-cancer cells from dying. "Notch proteins appear to sh...

Metal homeostasis research in plants will lead to nutrient-rich food and higher yielding crops

...lows these plants to take up iron and renders them resistant to Cadmium. Transgenic seedlings have Cadmium levels similar to that of IRT1 loss of function plants, demonstrating that Cadmium transport through IRT1 has been eliminated. Furthermore, these plants have twice as much Iron as wild type plants when g...

Ready, set, mutate?and may the best microbe win

...tations that pathogens will use in order to become resistant to antibiotics." Rice's study involved the heat-loving bacteria G. stearothermophilus, which thrives at up to 73 degrees Celsius (163 F). Shamoo and graduate students Rafael Couñago and undergraduate Stephen Chen used a mutant strain of the microbe ...

Study details hepatitis C ability to block immune system response

...us can persist indefinitely, indicating that it is resistant to their antiviral effects." The current study sh...virus has other tricks up its sleeve that makes it resistant to their antiviral effects. Further study is needed to understand which cells in the liver produce t...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...d up in experiments with ovarian cancer cell lines resistant to docetaxel and to the chemotherapy drug cisplatin. The FAK-silencing liposome and the liposome with chemotherapy also reduced the incidence of cancer by between 20 and 50 percent in all tested cancer lines. In addition to its anti-tumor effect...

Over-use of antibiotics in fish-for-food industry encourages bacterial resistance and disease

...rial resistance and could lead to the evolution of resistant strains of bacteria in animals and humans as well ...urvive in the presence of antibiotics - antibiotic resistant bacteria. Eventually this process could lead to increased antibiotic resistance in the 'disease-cau...

Researchers develop flood-tolerant California rice

...lleagues plan to work on developing crops that are resistant to multiple stresses. "For example, we'd like to develop rice that is both submergence and salt tolerant," she said, "given that many flood-prone areas are a mixture of fresh and salt water." Besides Bailey-Serres, Takeshi Fukao of UCR; and Kenong ...

U of M researchers discover genetic key to treating deadly fungal infections

...nding may yield clues about how some tumors become resistant to chemotherapy and how researchers can develop co...available to treat it and the fungus often becomes resistant to a drug, making it ineffective. The cost to the U.S. health care industry is $1 billion per year. ...

Montreal researchers identify defects of immune cells

...s often complicated by strains of Candida albicans resistant to conventional antifungal therapies. The research project was carried out jointly by Dr. Louis de Repentigny, Director of the Medical Mycology Laboratory and Professor in the Department of Microbiology and Immunology at the Faculty of Medicine of Un...

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