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Tag: "resistant" at biology news

Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm

...ations," she says. "Compaction may keep the genome resistant to damage of all kinds. This is critical ?if the single-stranded DNA in gametes breaks, it can fall apart and possibly reassemble itself in devastating translocations." She notes that normal double-stranded DNA, on the other hand, has the ability to...

Does natural selection drive the evolution of cancer?

...tion of tumor cells, you're quite likely to have a resistant mutant somewhere in that population of billions or...en able to cure cancer is that we're selecting for resistant tumor cells. When we spray a field with pesticide, we select for resistant pests. It's the same idea...

World-wide warning of highly drug-resistant tuberculosis

...sess the extent of the spread of these highly drug resistant strains of tuberculosis worldwide and improved mea...outh Africa earlier this year, 41% were multi-drug resistant and of those, 24% met the exact definition of being extensively drug resistant tuberculosis (also re...

Cancer stem cells linked to radiation resistance

...t the researchers studied, glioblastoma, is highly resistant to radiation and other forms of treatment and is t...ntly, scientists knew little about what made these resistant cells different from those that succumb to radiation treatment. It was clear, however, that the cell...

Search on for treatment of slow-healing wounds

...communities that can be 1000 times more antibiotic resistant than free-floating bacteria. "If you accept the biofilm theory of chronic wounds, it explains a lot," said Garth James, director of medical projects at the CBE. "It explains why these wounds are slow to heal. It explains why they recur. It explain...

Jefferson scientists find aging gene also protects against prostate cancer development

...ing a mutation for the androgen receptor, which is resistant to current forms of therapy, we can almost complet...r cells can express a mutation that makes patients resistant to current forms of treatment such as hormonal therapy. Such therapy focuses on inactivating the and...

Cloning techniques produce FDA-approved antibiotic

...alth, and demands new treatments effective against resistant pathogens. Fosfomycin is a natural antibiotic appr...e for the treatment of infections that have become resistant to the antibiotics penicillin and vancomycin. Fosfomycin is a member of a class of compounds calle...

New path from estrogen to survival in breast cancer cells described

...d in general, the more NFkB is expressed, the more resistant the cell is to apoptosis. Estrogen, a hormone that acts as growth fuel for about 70 percent of breast cancers. Researchers are interested in ways that cells can efficiently turn genes on or off, and one of the newest mechanisms is dubbed "NEDD...

Resistant bacteria increasing source of muscle infection

...ere forms of staphylococcal bacteria that were not resistant to methicillin, an antibiotic. It is important ...s cellulitis to use antibiotics that will cure the resistant forms of the bacteria, said Pannaraj. "Be aware that this is out there," she said. "When someone ...

Jumping gene could provide non-viral alternative for gene therapy

... produce a desired change, such as making the cell resistant to damage from radiation therapy. They found the piggyBac transposon was five to 10 times better than the other circular pieces of DNA at making a home and a difference in several mammalian cell lines, including three human ones. "If we want to a...

Looking to a new era in bee research

...faced by honey bees, including analyses of disease resistant pathways and metabolic adaptations to an all floral diet. Several papers address ways that honey bee studies can provide insights into human health. These papers cover the genetic bases of honey bee venom allergens, along with mechanistic insights i...

UGA scientists engineer root-knot nematode resistance

...an Rex Allen, Hussey discovered how to make plants resistant to root-knot nematode infection. Eric Davis at No...d reducing growers' losses, he said, is to develop resistant plants that prevent the nematode from feeding on the roots. Because root-knot nematode resistance do...

Air travel and pandemic flu

...the cities, and the fact that some people are more resistant to infection than others. From the use of their mathematical model, the researchers concluded that restrictions on air travel would achieve very little. This is probably because, compared with some other viruses, the flu virus is transmitted from ...

Scientists use gene signatures to match cancer and other diseases with potentially effective drugs

... of ALL, but in some patients the cancer cells are resistant to the drugs, which often can lead to fatal result... "We took cells from ALL patients that were either resistant or sensitive to glucocorticoids and put them through the Connectivity Map database, and it predicted...

MIT engineers probe spiders' polymer art

... be flexible or stiff, water-soluble or insoluble, resistant to heat and chemicals and very strong. Silk protein solution consists of 30-40 percent polymers; the rest is water. The spider's silk-producing glands are capable of synthesizing large fibrous proteins and processing those proteins into an insolub...

MRSA vaccine shows promise in mouse study

...rries lung-damaging toxins. All five strains were resistant to most of the drugs used to treat S. aureus infections. "This microbe's ability to acquire the tools it needs to protect itself from the drugs we use to treat it is legendary," said study director Olaf Schneewind, M.D., Ph.D., professor and chairm...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

... crop yields or enable growers to make plants more resistant to drought, pathogens, and cold weather. Unfortunately, synthesizing brassinosteroids in the lab is complicated and expensive. But understanding how plant steroids work at the molecular level may one day lead to cheap and simple ways to bulk up cro...

Salk scientists untangle steroid hormone signaling in plants

... crop yields or enable growers to make plants more resistant to drought, pathogens, and cold weather. Unfortunately, synthesizing brassinosteroids in the lab is complicated and expensive. But understanding how plant steroids work at the molecular level may one day lead to cheap and simple ways to bulk up cro...

Tests may help answer questions about GMOs and allergies

...his is usually done to create a plant that is more resistant to insects or diseases. The Food and Agriculture Organization within the World Health Organization has a structured approach to determining whether genetically engineered foods cause allergies, according to Gangur, who also is a faculty member in th...

Liquorice cancer care

...able for most patients, and liver tumours are very resistant to chemotherapy. The American Cancer Society estimates that 18,510 new cases of primary livercancer and bile duct cancer will be diagnosed in the United States during2006, and around 16,200 people will die of liver cancer. Studies in mice by Zhi Yua...

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