Selectively blocking inflammatory signals may protect mice from MS
...amage. But if stem cells could be engineered to resist harmful signals such as interferon-gamma, they might be protected from the "harsh environment" present in immune mediated demyelinated lesions, said Popko. ...Knowledge of dendritic cells branches out
... T cells then eliminate the existing infection and resist any future attack by memorizing that infection. DC also have an important educative role to play in preventing autoimmune diseases, such as type 1 diabetes and Multiple Sclerosis, where the body's immune system mistakes "self " for "foreign " and l...MRSA vaccine shows promise in mouse study
...drug-resistant. By 2004, 63 percent had learned to resist the antibiotics commonly used to treat them. While such methicillin-resistant Staphylococcus aureus (MRSA) infections have long been a problem in hospitals, nursing homes and dialysis centers, more and more healthy people with no apparent risk fa...Scientists resuscitate a 5 million-year-old retrovirus
...ably because host cells have evolved mechanisms to resist uncontrolled virus propagation, as has been repeatedly observed for retroviruses from experimental animals. "Phoenix has produced some 'genomic offspring' that may be responsible for the synthesis of the retroviral particles that can be observed i...A simple feedback resistor switch keeps latent HIV from awakening
...hat this simple resistor system was better able to resist environmental fluctuations than hypothetical oligomer-dependent switches, and cell-sorting experiments confirmed this prediction. This simple switch, in which the deactivating reaction overpowers the activating rea ction under most circumstances, ...Researchers use multiphoton microscopy to watch chromosomes in action
..., it will produce proteins that will help the cell resist stress," said Webb, Cornell professor of applied physics and the S.B. Eckert Professor in Engineering. The process is triggered by a molecule called heat shock factor (HSF), which interacts with genes to cue the synthesis of new proteins. But this we......ncer cells mutate to evade the body’s defenses and resist treatment with drugs. The Stowers researchers used the benign budding yeast Saccharomyces cerevisiae as their model organism and deleted a key cell division gene called MYO1. Surely, eliminating this important gene would shut down cell division...'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance
... advantage to their hosts - such as the ability to resist antibiotics. Plasmids are useful tools for genet...ted bacterial pathogens that lacked the ability to resist over-replication. "We harnessed this plasmid," thought Filutowicz. "Now, how can we use it?" The a......e for this effect in biomaterials ?small particles resist failure better. Scientists carried out experiments on ID2 beamline at the ESRF. They tracked the molecular and supramolecular rearrangements in bone while they applied stress using the techniques of X-ray scattering and diffraction in real tim...Minuscule molecules pack a powerful punch
...man autoimmune disease. They are also less able to resist infection by bacteria, such as Salmonella. The tea...e significant: the knockout mice were less able to resist infection by bacteria than mice with normal miR-155, producing lower levels of antibody and a reduce...Organic is healthier: Kiwis prove that green is good
...wis had thicker skins, which could help the fruits resist insects, and higher antioxidant activity which is thought to be a natural by-product of stress. However, some people are still unsure about the potential benefits of antioxidants and other compounds elevated in organic farm produce. Carl Winter, ...Leukemic cells find safe haven in bone marrow
...and leukemic cells grow. "Leukemic cells that resist asparaginase and survive in this protective niche of the bone marrow might be the reason that leukemia recurs in some children who have been treated with this drug," said Dario Campana, M.D., Ph.D., a member of the St. Jude Oncology and Pathology dep...Will the plague pathogen become resistant to antibiotics?
...lps bacteria commonly found in US meat and poultry resist several antibiotics has also been found in the pla...ene sequence researchers report. The ability to resist many of the antibiotics used against plague has been found so far in only a single case of the disea...Strawberry daiquiris -- the extra-healthy cocktail?
...n the fruit. While such a boost helped the berries resist decay, the same compounds would also be expected to make the strawberries healthier to eat. Dr Korakot Chanjirakul and colleagues at Kasetsart University in Thailand, in collaboration with scientists at the United States Department of Agriculture,...The price of vanity: Mating with showy males may reduce offspring's ability to fight off pathogens
...make her daughters and granddaughters less able to resist pathogens, Mank argues. However, there may be some benefits for the females. For example, females are larger than males in many fish species, perhaps because of the requisite energetic burdens of producing massive amounts of roe, and elevated tes...Why doesn't the immune system attack the small intestine?
...icrobial agents such as bacteria, teach T cells to resist attacking healthy intestinal cells." In the new study, Turley and her colleagues found that, in fact, dendritic cells aren't essential in creating tolerance in T cells. Instead, and unexpectedly, tolerance is produced by stromal cells from nearby l...New study sheds light on 'dark states' in DNA
...my of Sciences. "We want to know, what makes DNA resist damage by UV light?" said Kohler. "In 2000, we showed that single DNA bases can dissipate UV energy in less than one picosecond. But now we know that there are other energy states that have relatively long lifetimes." "Now we see that there is a fa...Herpes infection may be symbiotic, help beat back some bacteria
...ce with chronic herpes virus infections can better resist the bacterium that causes plague and a bacterium that causes one kind of food poisoning, researchers report in this week's Nature. Scientists at Washington University School of Medicine in St. Louis attributed the surprising finding to changes in th......e most heterozygous individuals are better able to resist these diseases,” explains Renaud Kaeuffer. The researchers stress the point that the genetic variety of the mouflons on the Kerguelen Islands is still less than what could be observed in a larger population. Very few researchers have carried out ...