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Tag: "reside" at biology news

Targeting tumors the natural way

... Because target receptors on cancer cells usually reside on healthy cells, too - albeit in lower numbers - therapies aimed at these receptors are always expected to have debilitating side effects. That's why Kiessling's approach holds such promise. "What we've shown is that you don't need a receptor that...

Viral protein is an effective preventative against infection

...moniae, aren’t transmitted at school. They already reside on the mucosal membranes in the nose, waiting for their chance to strike. When a child catches the flu, or another virus that causes an upper respiratory infection, the bacteria seize the opportunity and migrate to the middle ear, causing a secondary...

Brain networks strengthened by closing ion channels

...ivated cyclic nucleotide-gated channels (HCN) that reside on dendritic spines, the tiny protrusions on neurons that are specialized for receiving information. These channels can open when they are exposed to cAMP (cyclic adenosine monophosphate). When open, the information can no longer flow into the cell, ...

Stem cell transplants explored at Stanford as a possible treatment for hearing loss

...attention in 2003 for identifying stem cells that reside within the inner ear. Since then, his research has focused on using these stem cells to regenerate the critically needed hair cells in the inner ear. Later in 2003, his group reached another significant milestone: the team demonstrated that it is ...

New molecular pathway could reveal how cells stick together

... The job of MMPs is to cleave other proteins that reside in the space in between cells. Page-McCaw has previously identified a specific protein, called ninjurin, that gets cut by MMP. Now she is working out the interplay between MMPs and ninjurin, with the goal of characterizing this previously unknown pat...

New mechanism for nutrient uptake discovered

...like protein structures called transporters, which reside at the surface of the cell's outer membrane. Each pore is capable of transporting nutrients individually, so we were really surprised to find that the pores simply can't act without stimulation from their neighbors." In earlier research the Carneg...

Cancer-killing invention also harvests stem cells

...he type used in hospitals today. This shunt would reside on the exterior of the arm or be implanted beneath the skin. Some of the blood flow would bypass the capillary bed and instead go into the shunt, which could remain implanted for many weeks, continually removing and killing cancer cells. King's fir...

Type of stem cell found to reside in transplanted lungs

...tes for the first time that these progenitor cells reside in adult organs and are not derived from bone marr...not derived from bone marrow, but rather that they reside ?sometimes for many years ?in the lungs. The researchers also found that these cells have the capaci...

Despite their heft, many dinosaurs had surprisingly tiny genomes

...o the bone cells called osteocytes. These cells reside in individual lacunae, small pockets inside bone tissue. This uniquely durable cellular housing allowed the scientists to look back in time at the size of 31 extinct species' genomes: By measuring lacunae in dinosaur and extinct bird specimens housed...

Brain's white matter -- More 'talkative' than once thought

...red into action. To learn more about OPCs that reside in the brain’s white matter, the Johns Hopkins researchers measured activity from individual precursor cells in the corpus callosum, a region of white matter that connects the two brain hemispheres. To their surprise, OPCs were found to have electric...

Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness

...nathan Stamler M.D. G-protein coupled receptors reside on the cell surface where they interact with all manner of stimuli, including circulating factors such as adrenaline, as well such diverse sensory signals as odorants and light. The activation of these receptors leads to the propagation of intracellu...

How 'memory' T cells curb the spread of viruses throughout the body

...lymph nodes are not just organs where immune cells reside and proliferate, but also are the sites where a ma...ct, prevent viral diseases. CD8 T cells normally reside in lymphoid organs such as the lymph nodes. It was thought that to protect from disease, memory CD8...

Loss of stem cells correlates with premature aging in animal study

...stem cells, a deterioration of pools of cells that reside in each tissue type,” says Brown. We accelerated the aging process by wiping out a large fraction of these cells prematurely, in one fell swoop. Essentially, these mice start their young adulthood with two strikes against them in terms of long-term t...

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