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Tag: "reservoirs" at biology news

Loss of stem cells correlates with premature aging in animal study

...ent leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body’s response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans. This work appears in the inaugural issue of Cell ...

The quest for an effective HIV vaccine presents new possibilities, challenges

...s, spreads throughout the body and establishes HIV reservoirs in lymphatic tissues. Within weeks of exposure, virus levels peak and then decline to levels that may remain low for months or years. It is believed that CD8+ T cells--so-called killer T-cells--are responsible for this reduction in HIV levels; howeve...

Anti-wrinkle compound causes pathological reaction in skin cells

...kin cell vacuoles called fibroblasts, which act as reservoirs and interface between the inside and the outside of the cell. In the hours following the application of DMAE, the researchers observed an important slowing down of cell division—sometimes coming to a complete stop, the inhibition of certain metabo...

Swimming 'to the left' gets bacteria upstream, and may promote infection

...his allows the bacteria to eventually locate large reservoirs with richer sources of food and better conditions for multiplying. "We think that upstream swimming of bacteria may be relevant to the transport of E. coli in the urinary tract," said Köser. "It might also explain the high rates of infection in c...

Fight weeds with plant pathogens

...nt and animal species. In addition, weeds serve as reservoirs for plant pathogens that impact crops. According to Rosskopf, there are two approaches used for managing weeds with plant pathogens-the classical biological control approach and the bioherbicides approach. The classical biocontrol approach uses a ...

A key antibody, IgG, links cells' capture and disposal of germs

...partments then fuse with lysosomes, toxic cellular reservoirs that kill and degrade the sequestered antigens by flooding the phagosomes with acid and destructive proteins. IgG, Nohturfft and his colleagues report, plays a key role in this merger of phagosomes and lysosomes into the so-called phagolysosomes t...

Common cold virus leads to death in lung transplant patients

...ction suggests that certain cases can act as viral reservoirs to sustain transmission of rhinovirus. "Therefore, in lung transplant recipients with severe immunosuppression, clinical rhinovirus infection needs to be considered," said Dr. Kaiser. "This point might have substantial implications in terms of dia...

A new view on Lyme disease: Rodents hold the key to annual risk

...y other small animals, which in turn provide large reservoirs for B. burgdorferi. Acorns will not be a universal predictor of risk, the researchers acknowledge, since the disease occurs in areas without oaks. But the strength of these findings suggests that the observed link between increased Lyme disease risk ...

HIV infection requires an accomplice: B cells with special protein direct HIV to T cells

...studies and drug development efforts that focus on reservoirs of HIV in cells other than T cells," said Charles R. Rinaldo, Jr., Ph.D., professor and chairman of the department of infectious diseases and microbiology at Pitt's Graduate School of Public Health (GSPH) and the study's senior author. Nearly all a...

Microbes hitchhike across Atlantic on desert dust

...antic transport of dust could be a vector to renew reservoirs of some plant and animal pathogens in North America and could also be the cause of new diseases," says Griffin. ...

Progress being made in exploring potential use of stem cells to treat heart disease

...enerative Medicine. "The adult heart seems to have reservoirs of cardiac progenitor cells--adult stem cells that are destined to become cardiovascular cells--that may be able to replace a slow loss of cells over a lifetime. The coming years will undoubtedly bring new developments and technologies to unravel the...

Plants used to detect gas leaks, from outer space!

... if CO2 is sequestered indefinitely in underground reservoirs then it can't be acting to absorb heat in the earth's atmosphere. "Our own research attempts to address some of the issues related to public acceptability and safety: Will there be leaks? What environmental effects will any leaks have? Can we detect...

Contaminants linked to sturgeon decline in Columbia river

...chreck and Feist studied white sturgeon from three reservoirs along the Columbia River and from areas downstream.... The researchers found some of the fish living in reservoirs behind the dams had concentrations of chemicals up to 20 times higher than the fish below Bonneville...

Deep-rooted plants have much greater impact on climate than experts thought

...e tap roots transfer rainwater from the surface to reservoirs deep underground and redistribute water upwards after the rains to keep the top layers moist, thereby accentuating both carbon uptake and localized atmospheric cooling during dry periods. The researchers estimate this effect increases photosynthesis...

Ocean virus identified in human blood samples

...mpany. Researchers say that Vesivirus has natural reservoirs in the marine community where it can replicate and recycle, infecting and sometimes causing health problems in seals, sea lions, whales, and perhaps fish, shellfish and other species. In general, the marine environment is "a relatively under-explored...

The reason why antiviral therapy can't annihilate HIV infection, and what to do about it

... in affected patients. But the existence of viral reservoirs precludes the complete elimination of HIV from treated patients. In a new study appearing on November 1 in The Journal of Clinical Investigation, Tae-Wook Chun and colleagues from the NIH offer new insight into the eradication of HIV in infected indi...

New vaccine platform may fight infections with causes from influenza to bioterrorism

...ns, HIV and children with leukemia. Without normal reservoirs of these particular T-cells that are key to immune responses, these patients are unable to stave off an infection that in most people causes, at most, a bad cold. The findings are being published in the December 1 issue of the journal. The manuscri...

Applying ecological laws to bacteria

...lso be applied to bacteria living in the sump tank reservoirs of machines in an engineering workshop in Oxford, ...f bacteria living in oil-based metal-cutting fluid reservoirs were similar to those found in higher animal and plant communities. This confirms the ecological law...

New antibody shows promise as cure for anthrax

... only trace amounts of anthrax residing in typical reservoirs for the bacteria, the lungs and spleen. Iverson cautions it's not yet clear that this antibody treatment is as effective as the IgG antibody produced by Elusys, and that he and his collaborators are doing more studies to confirm that. The researche...

Past droughts geographically widespread in the West, according to tree-ring data

...bove-normal runoff season since 1998 -- filled the reservoirs on the Salt and Verde rivers, stream flows into the Salt and Verde have been below normal for eight of the last 10 January-through-May runoff seasons. Phoenix-based SRP is the largest provider of water to the greater Phoenix metropolitan area. The ...

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(Date:7/28/2014)... drugs already approved by the U.S. Food and Drug ... growth of certain bacterial pathogens inside human cells, including ... fever. The findings, published in mBio , the ... demonstrate a new way of identifying non-antibiotic drugs that ... A handful of drugs on the list inhibit the ...
(Date:7/28/2014)... of researchers led by the University of Arizona has ... genetic information will enhance scientists, and agriculturalists, understanding of ... enable the development of new rice varieties that are ... help solve global hunger challenges. , The paper, "The ... and evidence for independent domestication," was published online in ...
(Date:7/28/2014)... MIT professor John Essigmann and colleagues from the University of ... thought if they could induce the virus to mutate uncontrollably, ... a strategy that our immune system uses against many ... caused HIV to mutate at an enhanced rate, as expected. ... a small clinical trial reported in 2011. In a new ...
Breaking Biology News(10 mins):New route to identify drugs that can fight bacterial infections 2Generating a genome to feed the world: UA-led team sequences African rice 2Generating a genome to feed the world: UA-led team sequences African rice 3Generating a genome to feed the world: UA-led team sequences African rice 4Forced mutations doom HIV 2Forced mutations doom HIV 3Forced mutations doom HIV 4
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