Scientists Replicate Hepatitis C Virus in Laboratory
...bility to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this...f the human liver cells in the culture medium. The researchers believe that the HCV construct contained within the human liver cells behaved like a true HCV infect...Research advances quest for HIV-1 vaccine
... section of gp41 that the antibody recognizes. The researchers identified the specific amino acids on gp41 that 4E10 interacts with and the 3D structure adopted by these amino acids. These study results suggest that 4E10 interacts with gp41 at a conserved region very close to the surface of the virus and they re...Male circumcision reduces risk of HIV transmission from women to men
...t for differences in the risk ofinfection. But the researchers found that cultural differences insexual behavior did not matter: when groups of men were excluded fromthe analysis based on ethnic or religious characteristics, thedifference in probability of infection related to circumcision statusdid not change.I...Another Look Finds Promising Proteomics Test is Not Biologically Plausible
In a new study, researchers present a “cautionary tale?about what may go wrong...e of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an experimental test intended t...In a new study, researchers present a “cautionary tale?about what may go wrong...e of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an experimental test intended t...Cracking the olfactory code in bees
In a new study, researchers present a “cautionary tale?about what may go wrong...e of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an experimental test intended t...Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
...r samples could be accurately grouped together.The researchers also examined variations of individual genemeasurements to help determine causes of variability, and they foundthat laboratory practices comprised the smallest source of variation inthese studies. Measurement errors common to all labs were the next m...Signaling protein builds bigger, better bones in mice
In a new study, researchers present a “cautionary tale?about what may go wrong...e of the Journal of the National Cancer Institute, researchers from The University of Texas M. D. Anderson Cancer Center detail why an experimental test intended t...Scientists detect probable genetic cause of some Parkinson's disease cases
...ho do nothave a family history of the disease. The researchers found a mutationin one copy of the gene can lead t...a gene thatencodes a protein named dardarin by the researchers from the Basqueword dardara, which means tremor, a major symptom of Parkinson'sdisease. It was isola...Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
...have limited the application of this therapy.These researchers previously demonstrated that mouse embryonic stemcells can differentiate into neurons when cultured under specificconditions. These same culture conditions, technically simple andefficient, were recently applied to primate embryonic stem cells andres...Ecological destruction fuels emerging diseases
...argues that the real work has only just begun. The researchers still have a very poor to non-existent understanding of the roles these thousands of parasites play in different diseases, something that will require a detailed understanding of their often complex multi-host life cycles. "It's very difficult to li...Ancient olfaction protein is shared by many bugs, offering new pest control target
... In the new study, Vosshall, in collaboration with researchers from Sentigen Biosciences, showed that the function of Or83b is preserved in different insects. Although many odorant-receptor proteins appear to be species specific, there is a high degree of evolutionary conservation of the Or83b coding sequence am...Inexpensive, mass-produced genes core of synthetic biology advances at UH
... biology at the University ofHouston, now allowing researchers to inexpensively program the chemicalsynthesis of entire genes on a single microchip.Xiaolian Gao, a professor in the department of biology and biochemistryat UH, works at the leading edge of this field. Her recent findings onhow to mass produce mult...Study Links Ebola Outbreaks To Animal Carcasses
...dling of carcasses or bushmeat. Specifically, the researchers found that Ebola infections in wild animals such a...n the process. Between August 2001 and June 2003, researchers noted that wildlife outbreaks occurred prior to five human outbreaks in the same relative locations....Bacteria collection sheds light on urinary tract infections
... UTIs are typically treated with antibiotics. The researchers found that the E.coli causing the UTIs matched gen...les from dogs, cows, sheep, water and turkeys. The researchers then compared the samples genetically to the UTI causing bacteria and found that a sample from a cow...HIV Patients May Be at Risk of Heart Problems When Taking Protease Inhibitor Drugs
... University of Wisconsin, Madison, the Mayo Clinic researchers made the discovery about a class of prescription d...ra, Viracept, Crixivan, Norvir and Fortovase. The researchers emphasize that the drugs' therapeutic benefits are still greater than the risk of heart problems lin...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...d in making telomeres accessible totelomerase. The researchers found that both tankyrase 1 activity andtelomere shortening decrease the effects of telomerase inhibitors.Importantly, tankyrase inhibition enhanced telomere shortening upontreatment with a telomerase inhibitor and accelerated cancer celldeath."This ...GATA: a graphic alignment tool for comparative sequence analysis
...d in making telomeres accessible totelomerase. The researchers found that both tankyrase 1 activity andtelomere shortening decrease the effects of telomerase inhibitors.Importantly, tankyrase inhibition enhanced telomere shortening upontreatment with a telomerase inhibitor and accelerated cancer celldeath."This ...Whole genome fine map of rice completed
... was published in the Journal Science in 2002, CAS researchers have recently finished the fine map of the rice genome. In an article published by the recent issue of PLoS Biology (Vol.3 Issue 2, 2005), scientists led by the Beijing Institute of Genomics (BIG) reported a "much improved, near-complete genome analy......slows the rate of aging inroundworms, according to researchers at Washington University School ofMedicine in St. ... of them happened to have anti-aging activity."The researchers grew the roundworm C. elegans in the presence of the 19drugs and found that an anticonvulsant, ethos...