'Failed' experiment yields a biocontrol agent that doesn't trigger antibiotic resistance
... when he was puzzling over a failed experiment. A researcher in his lab had been trying to insert two different mutations into an ordinary bacterial plasmid - a routine task for the experienced scientist - but every attempt failed to produce a live bacterium. Plasmids are circular DNA molecules that are diff...Who gives stem cells their marching orders?
...dérale de Lausanne) professor Daniel Constam, lead researcher on the project. Constam adds that cells respond differently depending on the amount of time they have been exposed to the Nodal signal. One hallmark of aggressive cancer cells is their unspecified nature, similar to that of embryonic stem cells. Co...To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says
...the journal AIDS, was led by Douglas Owens, MD, a researcher at the Veterans Affairs Palo Alto Health Care System and professor of medicine at the Stanford University School of Medicine, and Margaret Brandeau, PhD, professor of engineering at Stanford. Estimates vary, but around 1 million Russians - sligh...Train your brain to hear your friends at a party
A major science prize was today awarded to a researcher who is looking for the region of the brain that he...e 2007 Pauline Ashley Prize to Sam Irving, a young researcher at the MRC Institute for Hearing Research in Nottingham. The Pauline Ashley Prize, established i...Memories: It's all in the packaging, scientists say
...d color," said Melina Uncapher, a graduate student researcher and lead author of the study. "This study provides empirical evidence for how critical this region is for bringing the constituents of a memory together in the brain. "Memory is more than a sum of its parts. A complete memory of an event requires ......," says study co-author Paul Rosenberg, MD, PhD, a researcher in the Neurobiology Program at Children's Hospital Boston, and a physician in the Center for Pediatric Sleep Disorders at Children's and in the Sleep Disorders Center at Beth Israel Deaconess Medical Center. In 1997, senior investigator Tarja Porkk...Sea urchin genome suprisingly similar to man and may hold key to cures
...ases, according to a University of Central Florida researcher and several colleagues. UCF Professor Cristina Calestani was part of the Sea Urchin Genome Sequencing Group, which recently completed sequencing of the sea urchin genome and published its findings in the November issue of Science. The National Insti...Researchers identify new weapon to fight deadly bacterial sepsis
... ability to pump blood is dangerous in itself, the researcher continued, and it can also have disastrous effects on the lungs and kidneys, which depend on efficient blood circulation. Srivastava, lead author Ramana and their collaborators injected mice with lipopolysaccharide (LPS) to produce the conditions...Scientists design simple dipstick test for cocaine, other drugs
...i Lu, a chemistry professor at the U. of I., and a researcher at the Beckman Institute for Advanced Science and ...r-linked nanoparticle aggregates, Lu, postdoctoral researcher Juewen Liu and graduate student Debapriya Mazumdar created highly sensitive and selective colorimetr...Study IDs protein that inhibits HIV from growing in cell cultures
...D., a VA research health scientific specialist, UI researcher and the current study's principal author. GBV-...y author Jack Stapleton, M.D., staff physician and researcher at the VA Iowa City Health Care System and professor of internal medicine at the UI Roy J. and Lucil...An advanced genetic diagnostic method for multiple myeloma
A researcher at the University of Navarra, Borja Sáez Ochoa, has proposed a new genetic diagnostic method for multiple myeloma (MM), a type of bone marrow cancer, which permits the detection of this disease in earlier stages. The dissertation of this biologist, ...New system could drastically reduce herbicide use
...d to the front of the machine engages a device the researcher calls "a custom-designed end effector." There are two layers to the device, according to Tian. One layer cuts the weed, while the second layer applies herbicide to the cut weed. "This type of application is extremely effective," said Tian, "bec...Biodegradable napkin -- featuring sensitive nanofibers -- may quickly detect biohazards
...g a napkin or paper towel across a surface, says a researcher from Cornell University. "It's very inexpensive, it wouldn't require that someone be highly trained to use it, and it could be activated for whatever you want to find," said Margaret Frey, the Lois and Mel Tukman Assistant Professor of Fiber Science...Rising ocean temperatures, pollution have oysters in hot water
...28° C (82° F) water died within 20 days, said lead researcher Gisela Lannig. Oysters exposed to cadmium at lower temperatures showed much lower mortality rate, suggesting that the combination of high temperature and cadmium is more stressful than each of these conditions alone, she said. The study "Temperat...SARS: No evidence that any of the treatments worked
... to be important in defense against pathogens. The researcher tested phytol, which increased oxidative burst in vivo, and found that it improved the arthritis in the mouse model with arthritis. In testing, also in mice, phytol showed comparative effectiveness to standard therapies for arthritis such as anti-tum...Climate change creates dramatic decline in red-winged black bird population
...al warming strikes again. A University of Illinois researcher reports that a red-winged black bird population in Ontario, Canada has decreased by 50 percent since 1972. The decrease is related to a positive shift in the North Atlantic Oscillation which has resulted in warmer, wetter winters in the southeastern ...Researchers make nanosheets that mimic protein formation
...evelop and test this hypothesis." Post doctoral researcher Zhenli Zhang of Glotzer's group tried various combinations of forces based on information gleaned from experiments performed by post doctoral Zhiyong Tang of Kotov's group. The team discovered that the unique shape of the CdTe nanocrystals gave rise ...High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
...d development of tailored treatments, according to researcher Levi A. Garraway, M.D., Ph.D., an assistant professor in the Dana-Farber Department of Medical Oncology. "It may help clinical testing of new targeted therapies, because patients can, in principle, be screened in advance for activating mutations in t...Biologists probe the machinery of cellular protein factories
...the paper, in addition to Noller, are postdoctoral researcher Andrei Korostelev, senior scientist Sergei Trakhanov, and postdoctoral researcher Martin Laurberg. The researchers used a technique called x-ray crystallography, which involves growi...Engineer ramps up protein production, develops versatile viral spheres
... they don't always tolerate the chemical changes a researcher needs to impose to make a specific product. Cell-free techniques, in contrast, can be more robust because they use just the protein-making machinery of cells. To harvest just the parts he needs, Swartz literally rips cells open by applying intense sh...