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Tag: "reproducible" at biology news

Cells re-energize to come back from the brink of death

... “The GAPDH response appears to represent a basic, reproducible event. But in order to verify that hypothesis, we’ll need to study it in the body, especially as we try to develop ways to force cancer cells without caspase to undergo CICD,” Green said. “Our goal is to find better ways to treat these diseases.”...

Extra-aggressive form of idiopathic pulmonary fibrosis identified

... part, the difficulty in obtaining significant and reproducible results in studies of therapeutic interventions in patients with IPF," said Dr Selman, who is the Director of Research at the National Institute of Respiratory Research in Mexico City and the lead author on this publication. "They also suggest that...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

... part, the difficulty in obtaining significant and reproducible results in studies of therapeutic interventions in patients with IPF, noted first author Moisés Selman, M.D., director of research at the National Institute of Respiratory Research in Mexico City. "This study suggests that physicians should pay more ...

Scientists clone mice from adult skin stem cells

...there are no reports on using adult stem cells for reproducible cloning of mice that survive until adulthood. By using cells from the same mouse and performing the experiments on the two successive days, the Rockefeller scientists could directly compare adult stem cells with other cell types. Nuclear transfer...

Insomnia drug can improve brain function

...ffect was due to zolpidem. "This phenomenon was so reproducible that caregivers used to give her up to three tablets each day without sleepiness as 'side effect,'" the authors state. The researchers systematically assessed the effect of zolpidem on motor and cognitive function and explored its effect on brain...

Computer imaging assists with facial reconstructive surgery

...e pupil. The porion-pogonion distance is a simple reproducible measurement that can be used along with established soft tissue measurements as a guide for profile facial analysis.?...

Embryos exposed in 3-D

... with increasingly stringent regulations for safe, reproducible and efficacious cell products. In addition to rapid processing, the Pall system can be performed at point of use (operating room). It does not require the addition of laboratory equipment or trained technicians, as the method is easy to learn and us...

New technology enables faster, more efficient cell harvest: Cell therapy meeting study

... with increasingly stringent regulations for safe, reproducible and efficacious cell products. In addition to rapid processing, the Pall system can be performed at point of use (operating room). It does not require the addition of laboratory equipment or trained technicians, as the method is easy to learn and us...

Ready, set, mutate?and may the best microbe win

...ests that the pathways of molecular adaptation are reproducible and not highly variable under identical conditions," Shamoo said. ...

Intensive statin therapy may partially reverse plaque build-up in arteries

...brand name Crestor®). IVUS provides a precise and reproducible method for determining the change in plaque, or atheroma, burden during treatment. Atherosclerosis progression was assessed at baseline and after at 24 months of treatment. "Previous similar studies with statins have shown slowing of coronary disea...

New journal article urges use of animal serum-free media for growing live cells

... into experiments, meaning that results are easily reproducible by different laboratories. ...

Diabetes researchers pioneer islet cell xenotransplantation in primate studies

... developed by the U of A researchers is simple and reproducible with the neonatal pig islets having some growth po...e that it is safe." Using a relatively simple and reproducible method of obtaining large numbers of islets from neonatal pig pancreata developed at the U of A, the...

Langerhans cells regulate immune reactions in the skin

...e response to contact hypersensitivity, we found a reproducible and significant increase," said first author Kaplan, assistant professor in the Department of Dermatology at Yale School of Medicine. "Langerhans cells are thus not required to generate immune responses in the skin and more profoundly, they actually ...

Prenatal exposure to marine toxin causes lasting damage

... the effects of a range of doses have found highly reproducible behavioral consequences of sublethal doses of the marine toxin, including impairments to spatial memory. To explore the toxin's effects during development, the Duke team administered domoic acid to pregnant rats at three levels -- each below those ...

Solexa and collaborating scientists illuminate the small RNA component of the transcriptome

...gy has the advantage of producing highly accurate, reproducible and quantitative readouts of the full complement of activated genes and small RNAs, including genes expressed at low levels, without requiring advance knowledge of the genes or sequences of interest. Solexa performed this research in its Genomic Serv...

The right drug at the right time

...of the spectrum as the crystals get smaller. The reproducible synthesis of high-quality quantum dots became a reality in the early 1990s when researchers at MIT pioneered a new method of producing quantum dots with uniform sizes and well-defined optical signatures. The basic recipe for making quantum dots hasn'...

Method slashes quantum dot costs by 80 percent

...of the spectrum as the crystals get smaller. The reproducible synthesis of high-quality quantum dots became a reality in the early 1990s when researchers at MIT pioneered a new method of producing quantum dots with uniform sizes and well-defined optical signatures. The basic recipe for making quantum dots hasn'...

'Mad cow' proteins successfully detected in blood

...nd validated the test to make it more rugged, more reproducible across laboratories, and more resistant to user error. They developed a clearly defined method for production of gamma phage that proved to be highly stable, as reflected in the extended shelf life of the B. anthracis-specific virus. USAMRIID then pr...

Anthrax test, developed by army and CDC, receives FDA approval

...nd validated the test to make it more rugged, more reproducible across laboratories, and more resistant to user error. They developed a clearly defined method for production of gamma phage that proved to be highly stable, as reflected in the extended shelf life of the B. anthracis-specific virus. USAMRIID then pr...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

... at Arizona State University has created the first reproducible single molecule negative differential resistor ?an... sulfuric acid solution, the team was able to make reproducible measurements showing all three states by measuring the current through it as electrons were removed ...

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