UCSB scientists probe sea floor venting to gain understanding of early life on Earth
.... The NSF explains that subseafloor ecosystems may represent both the cradle of life on Earth and a model for the exploration and discovery of life on other planets. "We are highly conscious of the importance of microbes in the grand scheme of things," said Haymon. "Indeed, they are the greatest biomass on th...Fox Chase Cancer Center scientists identify immune-system mutation
...id. The helper-deficient mice his team discovered represent the second time that a naturally occurring mutant strain has been found and bred at Fox Chase. In 1981, the laboratory group of Melvin Bosma, Ph.D., discovered mice with severe combined immune deficiency (SCID), a condition that also affects humans. ...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
...ell branches rapidly disappeared. "Theseswellings represent structural damage that seemed to be wellestablished and stable, but clearing out the plaques often led to rapidrecovery of normal structure over a few days," says senior author DavidH. Holtzman, M.D., the Charlotte and Paul Hagemann Professor and hea...Key molecule in plant photo-protection identified
...ell branches rapidly disappeared. "Theseswellings represent structural damage that seemed to be wellestablished and stable, but clearing out the plaques often led to rapidrecovery of normal structure over a few days," says senior author DavidH. Holtzman, M.D., the Charlotte and Paul Hagemann Professor and hea...Newly-discovered class of genes determines ?and restricts ?stem cell fate
...r or complex of factors to have this dual role may represent a new general paradigm for developmental and stem-cell biology. "My idea is that this is a new family of genes--they can both determine the cell type, but also put the breaks on differentiation," says Epstein. "We have named them pangenes, after the ...Study Links Ebola Outbreaks To Animal Carcasses
... proves that hunting and consumption of great apes represent a serious health risk for people in Central Africa, and a risk that can be avoided," said Dr. William Karesh, field veterinarian for the Wildlife Conservation Society and a co-author on the paper. "What we need now is improved awareness of this risk ...Spider Venom Could Yield Eco-Friendly Insecticides
...ins. Thousands of spider species yet to be studied represent an untapped reservoir of diverse insecticidal compounds that could do more than control agricultural pests. As researchers inventory more kinds of venom and uncover insecticide leads, they may be able to target insects that transmit new and emerging ...Open microfluidic and nanofluidic systems
...fabricated by available photolithographic methods, represent an appealing design principle for such microcompartments and, thus, provide a new route towards open microfluidic and nanofluidic systems. Scientists from the Max Planck Institute of Colloids and Interfaces, the Max Planck Institute of Dynamics and S...Researchers find missing genes of ancient organism
...the process of evolution," said Söll. "Or they may represent a specialization that has rid itself of genetic baggage to exist in extreme environments." Understanding how primitive organisms like Nanoarchaea operate gives clues to -- but not proof of -- the relationship between modern and ancient organisms. #...Scientists reveal molecular secrets of the malaria parasite
...pressed in the mammal hosts (human/mouse). Thatmay represent a mechanism by the parasites to repulse the attack of thehost's immune system. * For the first time, scientists were able tostudy the protein expression of the parasite in the mosquito vector.Researchers hope this will shed light on how the mosquito ...Circles Of DNA Might Help Predict Success Of Stem Cell Transplantation
... into any one of countless combinations. The rings represent sections of DNA cut out of chromosomes during the mixing and matching of genes that are chosen to build a particular receptor. Each T cell uses the resulting combination of genes to make a receptor that lets the cell recognize a specific target. When...The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
...al information on 4,000-6,000 unique proteins that represent the variety found in organisms ranging from bacteria to humans. Researchers can use these structures, which are determined experimentally, to build computer models of the structures of other proteins with related amino acid sequences. Although the m......after our Institute, termed ‘IBN-1?to ‘IBN-5? They represent a new class of materials that are tailored simultaneously with nanometer-scale particle size and nanometer-sized pores. This is a beautiful example of ‘bottom-up?nanotechnology made possible by supramolecular chemistry,?said Prof. Ying. Previous att...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...EL2 activity, since such an approach might one day represent an effective treatment for leukemia patients." Other authors of the report include Ayten Kandilci, Cintia Carella, Jonas A. Nilsson, Jennifer A. Brennan, Kelli Boyd, John Cleveland (St. Jude); and Sema Sirma and Ugur Ozbek (Istanbul University). ......e therapy proves to be safe and effective, it will represent an important new approach to improve the quality of life in these seriously ill patients with refractory chest pain," said Dr. R. Jeffrey Snell, study co-investigator and Schaer's colleague at Rush. In the new study, patients will be randomly assign...Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
...umor within a living rodent. Their findings, which represent a proof of principle for the use of emissive polymersomes to target and visualize tumors, appear in the Feb. 7 online early edition of the Proceedings of the National Academy of Science. "We have shown that the dispersion of thousands of brightly em...Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
...t particular antigens. The results from this trial represent a substantial step forward in this regard. This conclusion is justified because we are using reproducible immunological monitoring across the CVC, allowing a more accurate comparison of the effects of CpG 7909 in this trial with the results of severa...Discovery Promises Simpler Therapy for Sickle Cell Disease
...ive nitric oxide processing by red blood cells may represent a new class of blood diseases. Patients with sickle cell disease have an abnormal form of hemoglobin. In the late 1990s, Stamler's team discovered that, in addition to its role in oxygen delivery, hemoglobin acts a biosensor, adjusting blood flow ac...A human parasite with a streamlined mitochondrion
...eported by researchers this week, the mitosome can represent a surprisingly pared-down version of the much more... The work suggests that the Entamoeba mitosome may represent the simplest mitochondrion yet described, and thus it provides a model system for probing which mito......at time, the currently circulating strains may not represent the first HIV-1 lineages within the UK . If earlier strains existed they may have been unsuccessful in sustaining transmission to the present, although the absence of older strains could also reflect a sampling bias in this study. ...