Towards precise classification of cancers based on robust gene functional expression profiles
...t year at an ACS national meeting, the researchers reported they were able to prevent diabetes in a group of mice by using a synthetic compound called ISO-1 to block the MIF protein. If human studies prove the effectiveness of ISO-1, the compound or its derivatives could ultimately save lives, reduce health c...Antibiotic might fight HIV-induced neurological problems
...m the blood into the brain. Other researchers have reported that this antibiotic can protect brain cells in animal models of other diseases -- multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's disease, stroke and more. The drug is being tested in early clinical trials for some non-HIV-related con...Ophthalmologists implant five patients with artificial silicon retina microchip
...formed by Optobionics." The first 10 patients all reported some degree of improvement in visual function, says Pollack. "Improvement in visual function was variable and included the ability to read letters, improvement in color vision, and expansion of their visual field. Some patients gained new ability to ...Rats infected as newborns grew up vulnerable to memory problems during an immune challenge
...hers at the University of Colorado at Boulder have reported that rats who experienced a one-time infection as newborns didn't learn as well as adult rats who were not infected as pups, after their immunity was challenged. The research is in February's Behavioral Neuroscience, published by the American Psychol...Genetically modified rice in China benefits farmers' health, study finds
...netically modified insect-resistant rice varieties reported experiencing adverse health effects from pesticide... plots of conventional rice varieties, 7.7 percent reported pesticide-induced illness incidents in 2002, and 10.9 percent reported such cases in 2003. None of t...Use of Insecticides Linked to Lasting Neurological Problems for Farmers
...eir history of 23 neurological symptoms. Those who reported experiencing more than 10 symptoms during the year...ays in their lifetime. Nearly 800 of these farmers reported more than 10 neurological symptoms compared to those using insecticides fewer than 50 days. The rese...Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
...Coley Pharmaceutical), with a peptide antigen were reported today in the Journal of Clinical Investigation. The paper shows that the CpG 7909 DNA sequence is safe, and increases the immune system's ability to recognize and destroy cancer cells. The Phase I study was conducted by the Lausanne Branch of the Lud...Variation in women's X chromosomes may explain differences among individuals, between sexes
...tudy co-author Laura Carrel, Ph.D., of Penn State, reported their findings in the March 17, 2005, issue of Nat...than 250 researchers including Willard and Carrel, reported the complete DNA sequence of the human X chromosome. In animals, sexual identity is governed by sex...PET/MRI scans may help unravel mechanisms of prenatal drug damage
...Brookhaven National Laboratory, whose findings are reported in the February issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine, used positron emission tomography (PET) combined with magnetic resonance imaging (MRI) to track the uptake and distribution of trace amounts of cocaine in pregnan...Chemists identify immune system mechanism for methamphetamine binges
... to get high," says Janda. His findings were first reported in a recent issue of the Journal of the American Chemical Society, the Society's peer-reviewed journal. In a test tube study designed to simulate the chemical reactions that occur with the drug when it enters the bloodstream, the researchers showed ...HIV vaccine trial breaks ground for future research
...rld's first phase 3 HIV vaccine efficacy trial are reported in the March 1 issue of The Journal of Infectious Diseases, now available online. Although the vaccine was ineffective in preventing HIV infection, the trial represents a landmark in the fight against HIV and offers the scientific community a foundat...Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
...ith acquired immunodeficiency syndrome (AIDS) have reported increased risks of several cancers, including Kaposi sarcoma, non-Hodgkin lymphoma, and, to a lesser extent, anal cancer, invasive cervical cancer, and Hodgkin lymphoma. However, less well understood are the associations of these cancer risks with th...Discovery Promises Simpler Therapy for Sickle Cell Disease
...t Duke University Medical Center. The researchers reported their findings on Jan. 31, 2005, in an early edition of Proceedings of the National Academy of Sciences. The symptoms of sickle cell disease have generally been attributed to the physical obstruction of blood vessels by distorted, or "sickled," and ...Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
...D., a senior medical student. Their findings were reported in the June 2004 edition of Circulation Research, a journal of the American Heart Association. The study was funded by the National Institutes of Health. ...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
New work reported in the March issue of Cell Metabolism has provided insight into a key mechanism by which cells limit cholesterol synthesis. The finding suggests a novel approach to the development of cholesterol-lowering drugs that may boost the effect of statins, o...A human parasite with a streamlined mitochondrion
...at is evolutionarily derived from mitochondria. As reported by researchers this week, the mitosome can represent a surprisingly pared-down version of the much more sophisticated mitochondrion. In their new work on the mitosome, a team led by Edmund Kunji at the MRC Dunn Unit, Jorge Tovar at the Royal Hollowa...Increased risk of osteoporosis associated with gene that one in five people have
...ensity in the bones of the hip. The study will be reported in the February issue of the Journal of Bone and Mineral Research and is available online. The gene, named CYP1A1, makes an abundant enzyme that detoxifies foreign substances and also breaks down estrogen as a normal part of maintaining proper estr...WHO Warns Of Increased Risk Of Vector-borne Diseases In Tsunami-affected Areas
...eak last year. This year too, many cases have been reported in Jakarta, since December and the national authorities have installed control measures for these. However, given the extent of destruction due to the tsunami, WHO and the Ministry of Health are concerned about the increased risk of Dengue in Aceh an...Key mechanism in genetic inheritance during cell division identified
...t the Berkeley collaborators observed has not been reported for any other microtubule binding protein complex. While the authors say that ring formation is a complicated way to construct a microtubule binding structure, a microtubule binding ring might be uniquely suited to fulfill the functions of the Dam1 c......men, a significant increase in condom use has been reported since 1990, which could explain the equilibrium re...d. However, given that the first UK cases of AIDS reported in 1982 were probably infected within a window of 10 years prior to that time, the currently circula...