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Tag: "report" at biology news

Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

... of Cell, scientists led by Bruce Spiegelman, PhD, report that the harmful effects of saturated and trans fa...e effects than do saturated fats. The researchers report that when activated by harmful fats, PGC-1beta alters liver metabolism through a cascade of biochemi...

Spleen may be source of versatile stem cells

...at unexpected finding, members of thesame team now report that these potential adult stem cells produce apro... to produce an even greater variety oftissues. The report appears in the January 19 issue of SAGE KE , an online resource on the science of aging from the pu...

Yellowstone microbes fueled by hydrogen, according to U. of Colorado study

...lecular evolution and microbiology,published their report "Hydrogen and bioenergetics in the Yellowstonegeothermal system" this week in the online edition of the Proceedingsof the National Academy of Sciences.The team's findings, based on several years of research at the park,refute the popular idea that su...

It's not all genetic: Common epigenetic problem doubles cancer risk in mice

...Feb. 24 online version of Science, the researchers report that mice engineered to have a double dose of insulin-like growth factor 2 (IGF2) develop more so-called precursor cells within the lining of the colon than normal mice. When these mice also carried a colon-cancer-causing genetic mutation, they devel...

Topical treatment shown to inhibit HIV and herpes simplex virus infection

...r consent." According to the United Nations' 2004 report on the global AIDS epidemic, an estimated 40 million people worldwide are living with HIV, and women account for nearly half of those infected. As stated by the World Health Organization, unprotected sex is the predominant mode of HIV transmission, a...

New binding target for oncogenic viral protein

...hers at the Fred Hutchinson Cancer Research Center report the discovery of an additional target for T antige...Chemistry paper, Dr. Welcker and Dr. Bruce Clurman report that T antigen also binds to another tumor suppressor, Fbw7. This protein is part of a ubiquitin lig...

Lack of enzyme turns fat cells into fat burners

...ts, said Baylor College of Medicineresearchers.The report that appears online today in the Proceedings of the NationalAcademy of Sciences. "Westudied the fat cells in these mice bred to lack ACC2," said Dr. SalihWakil, chair of the BCM department of biochemistry and molecularbiology. "We found that the adi...

Fox Chase Cancer Center scientists identify immune-system mutation

... cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature. Kappes' laboratory first discovered the mice with this naturally occurring defect in Fox Chase's laboratory animal facility in 1997. Known as "helper deficient" or HD mice, they ar...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

...orizontal gene transfer into a protist, scientists report evidence in the DNA sequence that E. histolytica likely picked up a significant number of its metabolic genes from bacterial co-inhabitants of the human gut. Identification of these genes sheds new light on the unusual shared biology between the para...

Newly-discovered class of genes determines ?and restricts ?stem cell fate

... were on to something new." Epstein and colleagues report their findings in the February 24th issue of Nature. The scientists found that Pax3 plays dual ?and somewhat seemingly contradictory ?roles in adult stem cells: it directs them to become melanocytes, but simultaneously prevents them from differentia...

Scientists detect probable genetic cause of some Parkinson's disease cases

...482people with Parkinson's disease, but who didn't report a family historyof the disease. The Parkinson's Study Group is a non-profit,cooperative group of Parkinson's disease experts from 59 medicalcenters in the United States and Canada who are dedicated to improvingtreatment for people affected by Parkins...

Bound for destruction: Ubiquitination protects against improper Notch signaling

...rotected fromdigestion by that protease. Now, in a report published in the December29 issue of Current Biology, Shigeo Hayashi (Group Director, Laboratoryfor Morphogenetic Signaling) and colleagues at the RIKEN Center forDevelopmental Biology (Kobe, Japan) have identified the means by whichunstimulated cell...

Cytoplasm affects the number of vertebrae in carp-goldfish clones

...h 2005 issue of Biology of Reproduction contains a report of some intriguing findings in cloned offspring created when nuclei from one genus of fish were transplanted to enucleated eggs of another genus of fish. The seven offspring, cloned from nuclei of common carp and egg cytoplasm of goldfish, were virt...

Found: Missing sequence of the human Y chromosome

Scientists report today in the journal GenomeResearch that they have successfully cloned and characterized apreviously intractable DNA sequence: a 554-kilobase-pair genomicsegment near the centromere of the human Y chromosome. This sequencecontains eight putatively ac...

Novel Therapy Tested in Mice Could Chase Away Cat Allergies

...sity of California, Los Angeles (UCLA) researchers report in the April issue of Nature Medicine, available online now. In the future, the investigators say, these promising results could lead to a new therapy not only for human cat allergies, but also possibly for severe food allergies such as those to pean...

New Clues Add 40,000 Years to Age of Human Species

...f Utah and John Fleagle of Stony Brook University, report their findings in the Feb. 17 issue of the journal Nature. The fossils, from near the town of Kibish, are far more ancient than researchers originally suspected and nearly 40,000 years older than skulls from Herto, Ethiopia, the previous record hold...

Gene variations explain drug dose required to control seizures

...he National Academy of Sciences, the investigators report the first clear evidence linking variation in genes involved in the action or metabolism of the anti-epileptic drugs, carbamazepine and phenytoin, to the drugs' clinical use. The study is the first to emerge from a partnership, aimed at tailoring the...

Scientists collaborate to assess health of global environment

...cosystem Assessment program will issue its primary report on March 30 during press conferences in London, Wa... month's release of the global synthesis report. A report on global biodiversity will be available in May; a report on desertification is due out in June; and...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...rategy for Pompe disease patients, the researchers report in a forthcoming issue of Molecular Therapy (now available online). "Gene therapy in muscular dystrophies presents a unique challenge, because replacement of deficient, therapeutic proteins invokes an immune response that limits the efficacy of the ...

Enzyme shown to help protect genomic stability

...recombinations with other regions of the genome. A report on the research, which was conducted in yeast, appears in the February 18 issue of Molecular Cell. "There are regions of the genome that have to be inaccessible," says Shelley L. Berger, Ph.D., the Hilary Koprowski Professor in the gene expression a...

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