Scientists Replicate Hepatitis C Virus in Laboratory
...eplicated viral RNA supports a conclusion of viral replication and production.?/p> The NIDDK group used a strain of HCV that would have applications to the greatest number of people ?genotype 1, the major type of HCV of human infections worldwide and the type most resistant to current therapies. They constru......ses proliferate by hijacking their host cell's DNA replication machinery. In order to do this, they have evolved mechanisms to override normal cellular replication controls. Simian virus 40 (SV40) accomplishes this task by producing the highly oncogenic large T an...