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Tag: "replicate" at biology news

Key to early diagnosis of autism may be in the placenta

...ld be carefully checked." The Yale team plans to replicate the evaluation with larger multi-center and prospective studies. They will examine the placentas of the children in the study in greater detail to gain insight into the biological basis of the inclusions in ASD. Volkmar said, "If the work is confir...

Unusual mechanism keeps repair protein accurate

...ut that it is critical to the protein's ability to replicate DNA with very few mistakes." For this study, Suo and his colleagues wanted to learn how efficiently the new protein made new DNA. But the researchers initially considered the protein too large and difficult to produce in the laboratory. So instead...

Researchers seek to solve mystery of natural HIV control

...age to their immune system and could find a way to replicate that ability in others, we would have a recipe for halting the HIV epidemic," says Bruce Walker, MD, director of Partners AIDS Research Center (PARC) at Massachusetts General Hospital and an initial organizer of the Elite Controller Collaborative Stu...

Molecular DNA switch found to be the same for all life

...ate domains of life. "The ability of a cell to replicate its DNA in a timely and faithful manner is fundame...come two cells. A cell can't do this if it doesn't replicate its DNA in the right place, at the right time, and in the right manner, while simultaneously avoidi...

Gene therapy injected into the brains' of mice with Huntington's disease

... The vector is no longer a true virus as it cannot replicate on its own and no longer contains any of its own genes. The vector has been engineered to transfer the gene for the brain nutrient selectively to the area of the brain where it is needed to protect the degenerating cells. Three groups of mice were i...

Trials for new drug to overcome HIV

...verse transcriptase, an enzyme that enables HIV to replicate within cell. Others disable protease, which helps to assemble the virus into particles that infect other cells. Recent experiments in collaboration with Michael Sakalian and his colleagues at the University of Oklahoma Health Sciences Center in Okla...

Acid rain causing decline in sugar maples, say researchers

.... The scientists added nutrients in a test plot to replicate soil conditions that existed prior to the loss of sugar maples over the past 25 years. Nitric and sulphuric acid in acid rain leaches calcium from the soil. Calcium is the second most abundant plant nutrient (after nitrogen). In addition, the loss ...

Gene therapy prevents the onset of diabetic symptoms in mice

.... The scientists added nutrients in a test plot to replicate soil conditions that existed prior to the loss of sugar maples over the past 25 years. Nitric and sulphuric acid in acid rain leaches calcium from the soil. Calcium is the second most abundant plant nutrient (after nitrogen). In addition, the loss ...

On the golf tee or pitcher's mound, brain dooms motion to inconsistency

...eats consistency For athletes, the inability to replicate the perfect movement might seem to be a frustrating problem that needs to be solved. But the researchers speculate that the brain has evolved its apparently improvisational style precisely because the vast majority of situations requiring significant...

Human testis harbors HIV-1 in resident immune cells

...e cells in culture. The finding that HIV-1 can replicate within testicular macrophages is significant because the testis represents a pharmacological sanctuary—many anti-retroviral drugs have difficulty penetrating this organ and may be present at sub-therapeutic levels. Thus, although HAART may achieve u...

Insulin receptor stops progression of Alzheimer's disease

...neration. Scientists were also previously able to replicate Alzheimer's in rats with Streptozotocin (STZ), a compound that is known to destroy insulin producing cells in the pancreas and cause diabetes. When injected into the brains of rats, the compound mimicked the neurodegeneration of Alzheimer's disease ?...

Mars mission Risk 29: Scientists research ways to reduce radiation-induced brain damage

...of solar and cosmic radiation, Britten's team must replicate the type of radiation astronauts will be exposed to in deep space. They then must calculate how much damage is caused by particles with various energy levels. "There are only a handful of laboratories in the world where these kinds of high-energy ...

Researchers create genetically matched embryonic stem cells for transplantation

...ory at Children's Hospital Boston is now trying to replicate its results with human eggs. As Daley noted, there are several potential limitations to embryonic stem cells generated by parthenogenesis. First, since parthenogenetic embryonic stem cells are made from eggs, the technique is only applicable to fem...

New dyslexia theory blames 'noise'

...new study in Psychological Science was designed to replicate visual tests on motion perception from seminal experiments in the 1970s, with the addition of variable external noise. It also found no magnocellular deficit. "These were the stimuli people used to establish the magnocellular hypothesis," Lu said....

Research holds promise for herpes vaccine

...tenuated virus vaccines because the subunit cannot replicate or cause disease. However, subunit vaccines have proven ineffective in protecting people against persistent infections like genital herpes and AIDS, Halford said. "From a theoretical standpoint, subunit vaccines are poor mimics of a natural virus i...

HIV gets a makeover

...re-peg-round-hole conundrum. The HIV-1 virus won't replicate in monkey cells, so researchers use a monkey virus -- known as SIVmac, or the macaque version of simian immunodeficiency virus -- to test potential therapies and vaccines in animals. But therapies and vaccines that are effective on SIV don't necessar...

Study IDs protein that inhibits HIV from growing in cell cultures

...r therapies would target the cell in which HIV can replicate and not the virus directly. Therefore, HIV should have more difficulty developing resistance to the effects of this protein," Xiang added. Xiang previously discovered that GBV-C grows in the same type of white blood cells, CD4 T-cells, that HIV gr...

Rescuing injured hearts by enhancing regeneration

...eart-muscle cells (cardiomyocytes) normally cannot replicate in mammals, a major obstacle to regeneration. Howe...he findings suggest that getting cardiomyocytes to replicate is not enough to rescue heart function, but that angiogenesis is also needed, Engel says. "Regene...

GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science

...ngineering the yeast glycosylation system to fully replicate the full repertoire of human glycosylation reactions has been a challenging six year effort that many doubted could be accomplished," said Tillman Gerngross, Ph.D., chief scientific officer of GlycoFi and professor of Bioengineering at Dartmouth Coll...

Robotic whiskers can sense three-dimensional environment

... of robotic whiskers that in many respects closely replicate rat whiskers." The technology, she said, could be used to extract the three-dimensional features of almost any solid object. Rat whiskers move actively in one dimension, rotating at their base in a plane roughly parallel to the ground. When the wh...

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