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Tag: "replacement" at biology news

New research: Soy germ isoflavones reduce bone loss

...ficiency often acting as the major cause. Hormone replacement therapy has been the most effective treatment for ...sky side effects associated with long-term hormone replacement therapy use. This promising research is another step in advancing soy germ isoflavones as a safe, e...

Reversing 'hibernating' heart muscle focus of UB researchers

...n most circumstances do not appear to be caused by replacement with scar tissue. The new grant will allow researchers to determine if the metabolic changes that myocytes undergo in order to remain viable during hibernation limit their long-term ability to recover fully after revascularization. John M. Canty,...

Bioengineered tissue implants regenerate damaged knee cartilage

...ogress to osteoarthritis and the need for eventual replacement of the whole joint. Future investigations need to be carried out but this approach will allow us to improve further the outcome of cartilage repair." ...

Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check

...amp. The ubiquitin, in this case, serves to anchor replacement DNA polymerase molecules ?careless ones ?to the cl...aring stalled DNA polymerase out of the way so its replacement can get to work. Thus, these two proteins manage to help the body's cells maintain a crucial balance...

Fat stem cells being studied as option for breast reconstruction

...tructures will enable the production of a durable, replacement soft tissue. The team, led by J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the University of Pittsburgh School of Medicine, recently received a three-year grant from the National Cancer Institute to further explo...

Recycled paper and compost could both be key tools to control plant disease

...d Resource Action Programme (WRAP), found that the replacement of around 20% of the volume of soil or peat by compost gave major disease control benefits. Professor Ralph Noble's latest research appears to add another ecological benefit. Early results from trials with conifers using compost made from paper was...

A transplant in time

...st of risky blood transfusions or expensive enzyme replacement therapy. But what if the body could be induced to begin producing these proteins, say by transplanting healthy tissue with the abilities that are lacking? Prof. Yair Reisner and Ph.D. student Anna Aronovich of the Weizmann Institute's Immunology Dep...

Gene therapy for hereditary lung disease advances

...virus is intended to "infect" patients' cells with replacement genes that will do the necessary work to produce a...ed from 42 to 69 - were asked to discontinue their replacement therapy 28 days before receiving the gene therapy. One volunteer who had not been on protein repl...

Research links 'ecstasy' to survival of key movement-related cells in brain

...venting dopamine cells from dying or aiding in the replacement of those cells is key to finding lasting therapies. Lipton, director of the developmental neuroscience division in UC's psychiatry department, studies the long-term effects of abused drugs on the developing central nervous system. He noticed, durin...

Jefferson scientists find high glucose before surgery raises risk of dangerous complications

...agues examined records of nearly 6,500 hip or knee replacement surgery patients at Thomas Jefferson University Hospital who were admitted between 2003 and 2005. They asked what happened to patients with high blood sugar that wasn't well controlled prior to surgery. Of these patients, 38 had very high blood gl...

An artificial cornea is in sight, thanks to biomimetic hydrogels

...al cornea. "The dream would be to have a corneal replacement that's sterilized and dehydrated and sent off to the hospital or battlefield, and rehydrated," Frank says. Beyond blindness Other ocular applications of the hydrogel include more comfortable contact lenses. Onlays of hydrogel lenses on the surfa...

Replacing insulin is top-ranked breakthrough foreseen for health in developing world

...auses. It moves beyond traditional transplant and replacement therapies to include the use of stem cells, solubl... placed atop their list: "Novel methods of insulin replacement and pancreatic islet cell regeneration for diabetes." Many panellists noted the heavy health, soc...

Stem cells found in adult hair follicles may provide alternative to embryonic stem cells

...onic stem cells. "We see the potential for cell replacement therapy in which patients can be their own donors,...ble characteristics that could lead to local nerve replacement and re-myelination (restoration of nerve pathways and sheaths). Neural crest stem cells generate ...

Muscle and bone from an ink-jet printer

...ortant capabilities if researchers are to engineer replacement tissues that might be used in treating disease, trauma, or genetic abnormalities. Spatial patterning of stem cell differentiation through delivery of bio-inks with an ink-jet printer will offer the Pittsburgh researchers a whole new level of complexi...

A new approach to growing heart muscle

...ntists another step closer to the goal of creating replacement parts for damaged human hearts, or eventually growing an entirely new heart from just a spoonful of loose heart cells. This week, University of Michigan researchers are reporting significant progress in growing bioengineered heart muscle, or BEHM, w...

Natural protein stops deadly human brain cancer in mice

...like brain cells, which, instead of triggering the replacement of damaged cells, form cancer tissue. Stem cells, unlike all other cells in the body, are capable of forming almost any kind of cell when the right "signals" trigger their development. For their treatment experiment, the researchers relied on a c...

Growth factor stimulates rapid extension of key motor neurons in brain

...atment of spinal cord injury, and to the potential replacement of neurons using precursors or 'neural stem cells'," says Macklis, who is on the faculty at Harvard Medical School. ...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

... tissue, and can seriously impair the viability of replacement organs and jeopardize the health of the patient. The identification of Lcn-2 could be a first step towards reducing this inflammatory response and increasing the success rate of heart transplants worldwide. The study appears in American Journal of Tr...

Growth hormone is not the anti-aging bullet for healthy adults

... among the most expensive of all hormones used for replacement therapy. One physician estimated that a year's supply for an adult with GH-deficiency caused by pituitary disease would cost between $7,500 and $10,000 per year. Estimates of the cost of GH for anti-aging purposes range from $1,000 per month to $2,00...

Genes may determine success of hip replacement surgery

The success of long term hip replacement surgery may lie in the genes, suggests research pu...ust over half of whom (162) had problems after hip replacement in the 10 years following surgery. Among those with symptoms, 91 had early signs of “aseptic loos...

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