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Tag: "repairing" at biology news

Cells re-energize to come back from the brink of death

...f-destruction by increasing their energy level and repairing the damage, is giving investigators at St. Jude Children's Research Hospital insights into a key strategy cancer cells use to survive and thrive. The finding offers an explanation of how abnormal cells that have cheated death once by disabling the m...

Human stem cell treatment restores motor function in paralyzed rats

...ell transplants in the spinal cord have focused on repairing the myelin-forming cells,” said co-author Karl Johe, a researcher at Neuralstem, the company that manufactures the hSSCs used in the study. “In this study, we succeeded at reconstructing the neural circuitry, which had not been done before.” The r...

Gene thought to assist chemo may help cancer thrive

... but less attention has been paid to p53’s role in repairing damaged cells,”said John McDonald, chair of Georgi... p53 can also help repair damaged cells. If p53 is repairing cancer cells, that may lead to cancer recurrence. "We think p53 may actually help some cancer ce...

Intelligent materials to regenerate bone tissue

...al that is ‘intelligent? proactive, and capable of repairing and regenerating bone tissue. To this end, it has to be bioactive, capable of acting on the tissue-generating system and its corresponding genes, as well as respond appropriately to the physiological and biological changes, both internal and external...

Woven scaffolds could improve cartilage repair

...since the current approaches are only suitable for repairing smaller areas of cartilage damage or injury." Cartilage is a type of connective tissue that lines the ends of bones, providing cushioning and a smooth surface for their movement within the joint. Damage to cartilage is difficult to treat, the rese...

Liver regeneration may be simpler than previously thought

...ny organs, but in the case of the liver, the cells repairing it through regeneration may simply be regular cells, not stem cells. "We think that the liver regrows through a relatively simple process, which could explain its prodigious ability to repair itself," Karp says. ...

Swell gel could bring relief to back pain sufferers

...d by the urgent need for a non-surgical method for repairing intervertebral discs. "Our approach has the advantage of restoring spinal mobility whereas spinal fusion surgery results in a significant loss of mobility at the fused and adjacent discs." Dr Saunders said: "Although we are encouraged by our fi...

Scientists identify specific enzymes that make meningitis hard to fight

... realising that the two enzymes had distinct roles repairing different types of DNA damage, were able show the pathogen can 'fend off' different types of DNA damage while in the bloodstream. In theory, finding some way of disabling these enzymes would render the bacteria unable to repair itself, and therefore ...

Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration

...r success. This technique gives us new insights in repairing damage to the retina and possibly other parts of t...e now have proof of principle that our approach to repairing damaged retina by transplantation of appropriate cells can be successful." Swaroop sees several ...

Newts which regrow their hearts

...und no indication that stem cells were involved in repairing newt hearts. he process of regenerating lost e...in the newt will open up new possibilities for the repairing human patients’ damaged hearts. ...

First Quantum Grant to fund stem cell repair of damage from stroke

...s that will continue to develop and differentiate, repairing the injured tissue in the process. "This project represents an integrated effort among leading scientists who have jointly authored numerous publications, mentored students and postdoctoral fellows, as well as collaborated on Bioengineering Resear...

New sunscreen ingredient to heal sunburn and help prevent skin cancer

...ponents will not only contribute to preventing and repairing skin damage caused by UV light, but will also be more effective and will last longer (up to three hours) after application on the skin than conventional sunscreen lotions. Skin cancer is one of the most common cancers in the UK and the number of p...

Getting to the heart of the heart

... multiple cell types, they could be more useful in repairing the heart than any single kind of cell." Orkin c...nic development and represents another approach to repairing injured heart muscle. By apparently stimulating tissue regeneration, he was also able improve heart ...

Buildup of damaged DNA in cells drives aging

...d that mice completely lacking a critical gene for repairing damaged DNA grow old rapidly and have physical, genetic and hormonal profiles very similar to mice that grow old naturally. Furthermore, the premature aging symptoms of the mice led to the discovery of a new type of human progeria, a rare inherited d...

Age-related changes in DNA repair illuminate the connection between age and genetic damage

... of repair. Cells possess a variety of methods for repairing broken DNA, and the cell's "choice" of how to repair a particular break can be critical. Some repair methods are simple but error prone, whereas the more accurate methods have elaborate molecular requirements and are probably much slower. The new...

What animals can tell us about hemorrhage, organ transplants and aging

...mage to their genes and have a more difficult time repairing the damage than long-lived animals, the theory goes. Mice, a short-lived species, have a high occurrence of cancer, which is related to damage to the genes, while mole-rats appear to be cancer-resistant, Kristan said. On the other hand, long-lived an...

A surprise about our body clock

... important role of bone marrow adult stem cells in repairing a damaged heart, restoring its function and enhanc...od vessels in the heart. This is the first step in repairing the heart and in preventing the vicious downward spiral of heart failure in which the heart progress...

Healing the heart with bone marrow cells

... important role of bone marrow adult stem cells in repairing a damaged heart, restoring its function and enhanc...od vessels in the heart. This is the first step in repairing the heart and in preventing the vicious downward spiral of heart failure in which the heart progress...

Selectively blocking inflammatory signals may protect mice from MS

...these cells, called oligodendrocytes, incapable of repairing the damage but can also kill them directly. "Interferon-gamma is not normally found in the nervous system," said Popko, the Jack Miller Professor of Neurological Diseases at the University of Chicago, "but it can gain entry after an inflammatory fla...

Bedsores and bald hides: Novel roles revealed for a 'scaffolding' protein

...standing of the fundamental mechanisms involved in repairing wounds may lead to improved strategies for fostering proper healing with minimal scarring." K17's role in maintaining hair follicle strength is probably centered on its capacity to control the timing of follicle cell death during normal hair growth ...

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