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Tag: "repair" at biology news

Cincinnati surgeons report new treatment for often-fatal injury

...can form, which often bursts later. Surgeons must repair the damaged aorta quickly before it does rupture, ... method gives emergency surgeons a reliable way to repair difficult injuries with readily accessible materials," Dr. Giglia says. "More people can be treated-...

UC Davis study finds HIV hiding from drugs in gut, preventing immune recovery

...activity of genes that control and promote mucosal repair and regeneration were suppressed, while the genes ... She also pointed out that genes involved with the repair and regeneration of gut-associated lymphoid tissue would make excellent drug targets. Researchers...

Progress being made in exploring potential use of stem cells to treat heart disease

...ors that are sufficient to invoke cell survival or repair responses in damaged heart cells "The use of stem cells to generate replacement cells for damaged heart muscle, valves, vessels and conduction cells holds great potential," says Srivastava, who is also a UCSF professor of pediatrics and the Wilma...

Dartmouth study finds that arsenic inhibits DNA repair

...ssociated with a decrease in the body's ability to repair its DNA. "This work supports the idea that arsen...y studies to examine the effects of arsenic on DNA repair in cultured human cell models. "The DNA repair machinery normally protects us from DNA-damaging ag...

DNA: Bacteria's survival ration

...ells to assimilate waste DNA in order to mutate or repair their genomes. Natural competence is potentially risky, Finkel said, since bad mutations can result, "but there should be no genetic cost to eating [the DNA]." The study identified eight genes in E. coli that are necessary for nutritional competenc...

Unusual mechanism keeps repair protein accurate

...al Chemistry, provides new insights into how cells repair damaged DNA. "DNA is constantly attacked and da...iety of agents," Suo says. "The body must properly repair that damage, or it can lead to cell death or to cancer, birth defects and other diseases. "There ...

Mechanism identified for promising neurological drug

...likely be true of minocycline. And in blocking DNA repair you conceivably increase the risk of cancer. In clinical trials where people are taking minocycline for months at a time, I think that investigators need to take this into consideration ?although for someone with a serious neurodegenerative disease l...

DOE JGI finishes 100th microbial genome

...to render clean renewable sources of energy and to repair damaged environments, are among the many secrets encoded in their DNA sequence. On May 23, at the general meeting of the American Society of Microbiology (ASM), the U.S. Department of Energy Joint Genome Institute (DOE JGI) will announce that it has...

Cigarette smoke blocks cell repair mechanism, University of Florida study shows

...reast cells cancerous by blocking their ability to repair themselves, eventually triggering tumor developmen... smoke, can cause DNA damage and can block the DNA repair of a cell or compromise the DNA repair capacity of a cell. That can be detrimental for the cell and ...

'Signature' of chromosome instability predicts cancer outcomes

...or reshuffled to the wrong chromosomes. Cells have repair mechanisms that constantly fix this damage, but when the repair process breaks down, chromosomes become unstable and cancers are more likely to develop. Chromos...

Neurons grown from embryonic stem cells restore function in paralyzed rats

...bcAMP, growth factors, and cells to facilitate the repair of the injured spinal cord." Previous studies have shown that stem cells can halt spinal motor neuron degeneration and restore function in animals with spinal cord injury or ALS. However, this study is the first to show that transplanted neurons can...

Study links high levels of nitric oxide to infertility and sperm DNA damage

... NO and used a test that can detect DNA damage and repair in individual cells (single cell gel electrophoresis (comet) assay) to determine DNA damage. "We found that the NO levels in the infertile men were, on average, twice as high as in the fertile men," said Dr Amiri. "However, at this stage we were una...

Heal thyself: Systems biology model reveals how cells avoid becoming cancerous

...d eventually be used to develop drugs to boost DNA repair in response to environmental toxins and possibly t...mentosum, a disease in which the body's ability to repair DNA damage caused by ultraviolet light is disabled, ataxia telangiectasia, a progressive, neurodegen...

Pollution threatens coral health by preventing lesions from healing, UCF study shows

...l that were growing near both areas were unable to repair tissue damage, while coral colonies at control sit...coral to produce, leaving less energy available to repair damaged tissue. Fauth's team is sharing data with Professor Michael Risk of McMaster University in...

Study identifies new role for breast cancer susceptibility gene

...rve as a tumor suppressor by regulating DNA damage repair and maintaining genomic stability. Although the mechanism is not fully understood, reduced BRCA1 expression is also often correlated with accelerated growth and progression of breast tumors and with increased tumor blood vessel formation. In order to...

A protein complex that untangles DNA

...can be linked to erroneous copying, separation, or repair of the DNA molecule. By learning about the normal ...s the research group. Central to both chromosome repair and distribution during cell division are three related protein complexes. "Quite a bit is known ab...

Stem cells found in adult skin can be transplanted and function in mouse models of disease

...ram to determine whether human SKPs can be used to repair the injured spinal cord in rodents. The mission of NeuroScience Canada's Brain Repair Program is to fast-track neuroscience research in order to develop treatments and therapies more quickly. ...

Precision biochemistry tracks DNA damage in fish

...s on fish populations. Moreover, since natural DNA repair processes may gradually reverse the damage in the absence of further insults, these biomarkers also might be used to help assess the efficacy of pollution remediation efforts. The work was funded in part by the National Institute of Environmental Hea...

University of Minnesota researchers take new look at cellular suicide

...ed traitor, a protein whose regular job is to help repair severed DNA molecules will, in some cases, join forces with another protein to do the opposite and chop the DNA to bits, according to new research at the University of Minnesota. The chopping up of a cell's DNA occurs in response to damage, for examp...

Bone marrow may restore cells lost in vision diseases

...n, we should be able to harvest stem cells to help repair the damage," said senior author Edward Scott, Ph.D., a professor of molecular genetics at the UF Shands Cancer Center and director of the Program in Stem Cell Biology and Regenerative Medicine at UF's College of Medicine. "The question is whether we ...

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