Stem cell study for patients with heart attack damage seeks to regenerate heart muscle
...tem cells are designed by nature to perform tissue repair in a mature adult. It is believed that these cells can be used in patients unrelated to the donor, without rejection, eliminating the need for donor matching and recipient immune suppression. Once transplanted, the cells promote healing of damaged or...NJIT engineer poised to take stem cell research a step forward
...e technique of using nano-scaffolds can be used to repair injured spinal cords." Arinzeh's second $300,00...ir/Glen Ridge. Rizio, who specializes in cartilage repair and arthroscopic surgery, will design and interpret the animal models used to test the stem cell rep...A new focus for the mechanism of nerve growth
...ntrol of nerve growth, with particular interest in repair of spinal cord nerves after injury. ...Common enzyme is a key player in DNA repair
...quickly fixed by the cell's fleet of precision DNA repair processes, which can surgically excise and replace...ymerases comes to the rescue. They cannot actually repair a damaged strand of DNA, but they can smooth over the problem by inserting a nucleotide opposite the......ys. "We aren't sure why, but we think that the DNA repair machinery may be involved in processing the Z-DNA structure differently in bacteria versus human cells." Since formation of Z-DNA is naturally occurring and can exist in the genome, the scientists next want to understand why cells can sometimes proc...Removing DNA repair gene causes metabolic syndrome
...enerating mice that lack the gene encoding the DNA repair enzyme NEIL1 causes them to develop severe obesity...tty tissue. The results are the first to link DNA repair with the metabolic syndrome, and they suggest an important role for the NEIL1 gene product in the pr...Potential heart benefit found in stem cells
...rch on the efficacy of stem cell therapy for heart repair has shown benefit from mesenchymal stem cells (oft...ll eventually be able to use our own stem cells to repair our own heart dysfunctions," said Sunichiro Miyoshi, M.D., of the Keio University in Japan, and one ...Bioactive cement scaffold may improve bone grafts
...logy for implants that may improve construction or repair of bones in the face, skull and jaw, has been developed by researchers from the American Dental Association Foundation (ADAF) and the National Institute of Standards and Technology (NIST). Described in recent and upcoming journal articles,* the new...Study shows that cells have a natural defense against HIV
...ings indicate that two proteins that normally help repair cellular DNA can also destroy the DNA made by HIV ...Kristine Yoder discovered the role of the cellular repair proteins while trying to answer a different question. Before HIV infects a cell, it carries its ge...Measuring artery repair cells could become new heart disease test
...alized cells that circulate in the bloodstream and repair damage to the arterial lining has been discovered ...r levels of circulating EPCs would be less able to repair cardiac damage. Thus, they would be those with greater disease and at greater risk for a cardiac eve...New study reveals promising osteoporosis treatment
...te drugs and hormone therapies, do not effectively repair bone that has already been lost. In fact, bisphosp...h may also focus on using Mg/Zn/F-CaP compounds to repair fractures and periodontal bone defects. ...Bone and cartilage growth to blame for heart valve disease
...nnan. "Currently the only option is to surgically repair or replace the damaged valves. Our findings open ...eads to 100,000 surgeries in the U.S. each year to repair or replace damaged valves. Mitral valve disease is a leading cause of atrial fibrillation, which is...FDA approves first medical device using rutgers biomaterial
...ion's clearance of a new medical device for hernia repair that incorporates a biodegradable technology devel...tive medicine, in which materials help the body to repair itself and are then resorbed. The device consists of a surgical mesh coated with a polymer develop...Enzyme crystal structure reveals 'unexpected' genome repair functions
... critical to transcription and nucleotide excision repair (NER), as well as other cell processes. "XPB was...xposure to ultraviolet light." DNA needs constant repair because of the damage from a variety of sources that occurs to its base pairs of nucleotides. It is ...Manchester scientists create new bio-gel for 3D cell culture
...produced by the body to grow new cells in order to repair damaged tissue. Like the ECM, the gel acts like a scaffold in which cells can grow. In their paper, 'Nanostructured Hydrogels for Three-Dimensional Cell Culture Through Self-Assembly of Fluorenylmethoxycarbonyl-Dipeptides', Dr Rein Ulijn and collabo...VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum
...and an increased ability of the cell to process or repair the damage caused by the chemotherapeutic agent." "Our novel compound was designed to overcome resistance by emphasizing new modes of DNA binding, and in the process we have found that the amount of platinum drug entering cells is increased," he sai...Man-made heart tissue improves cardiac performance
...sed to treat cases of myocardial infarction and to repair congenital heart defects, as well as in the use of drug development to provide insight into cardiac developmental biology. ...Stem cells can repair torn tendons or ligaments
... least 200,000 patients undergo tendon or ligament repair each year. Moreover, the intervertebral disc, whic...ntil the present time, therapeutic options used to repair torn ligaments and tendons have consisted of tissue grafting and synthetic prostheses, but as yet, n...Value of services performed by insects tops $57 billion in US
...inue to do their beneficial work. "We know how to repair roads and other components of our physical infrastructure, but our biological infrastructure is vulnerable to degradation too," said Losey, an applied insect ecologist. "If we do not take care of it, it will break down and could seriously impact the ......die, or is initiated when a cell is damaged beyond repair or infected by a virus. Apoptosis is rare in cancer because tumor cells have adapted biological pathways to circumvent cell death, so many anti-cancer therapies focus on inducing apoptosis in these cells, Tang says. But the notion of how to push can...