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Tag: "repair" at biology news

Tsunami + 1 year: Reviving exhausted fisheries should trump replacing boats, gear, experts say

...ives and Sri Lanka. Officials estimate the total repair cost throughout the affected area at $5.8 billion, while a total of $4.4 billion has been committed to specific projects. There has been a total pledge of at least $7.5 billion from the following sources: multilateral donors $2 billion; bilateral don...

Clinical trial to test stem cell approach for children with brain injury

... bone, muscle and other organs, the brain does not repair itself effectively. Traumatic brain injury victim... novel treatment, the first ever with potential to repair a traumatically damaged brain," said James Baumgartner, M.D., associate professor of pediatric neuro...

Neurons generated in the adult brain learn to respond to novel stimuli

... our efforts, and those of others in the field, to repair diseased brain and spinal cord by directed development of specific neurons from precursor/stem cells. Our experiments show that new neurons can join brain circuits and function in complex ways ?contributing to learning, memory and potentially to moto...

Cells from amniotic fluid used to tissue-engineer a new trachea

Pediatric surgeon looks to fetal cells to repair birth defectsResearchers at Children's Hospital Bo...o the lambs while still in the womb. The tracheal repair technique is one of several tissue-engineering approaches pioneered at Children's that use the fetus...

New understanding of regeneration gained by Forsyth scientists

...ered how the worm's cells communicate to correctly repair and regenerate tissue. Forsyth scientists have found that gap-junction (microscopic tunnels directly linking neighboring cells) communication contributes to this signaling. This research, led by Dr. Michael Levin, underlies principles that can poten...

Discovering the first steps in transcription-coupled repair

...layers in the first steps of transcription-coupled repair (TCR), an essential but still mysterious mechanism...synthesis of proteins -- the transcription-coupled repair (TCR) process detects the obstruction and repairs the damage. But when TCR itself fails, the results...

Harnessing genomic research

...o understand why damaged nerve cells are unable to repair themselves. The work could lead to ways of stimulating nerves to regrow and repair damaged connections. Personalised cancer treatment- A large number of cancers are linked to mutat...

From one cell, many possible cures

A single cell with the potential to repair damaged heart muscle tissue . . . regenerate injured bone . . . create new cartilage or skin . . . even reverse nerve damage. Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of ot...

Feds give researchers ok for safety test of adult stem cells in patients with heart disease

...gured out how to initiate the sort of blood vessel repair that remains a key to survival," says Dr. Laughlin. "Now there is a promise of achieving that repair by infusing highly selected marrow stem cells." Upon acceptance in the study, patients with blocked...

OHSU discovery sheds light into how stem cells become brain cells

...plications for clinical application in spinal cord repair strategies." ...

Group proves it's possible to grow new lung alveoli by growing new blood vessels

...vent it, we've started to think about how we might repair it." Using animal models, Dr. Thébaud and a team of University of Alberta researchers have taken what they say is the first important step towards a treatment--in effect, growing new blood vessels and alveoli--the tiny air sacs where gas exchange oc...

Bioengineers create stable networks of blood vessels

... neuro-vascular niche and opens up ways to address repair of severed nerves," said Joseph Madri professor of pathology at Yale School of Medicine and a co-author. "We can now study what affects the attraction and repulsion of nerve growth and drug delivery in a model system that can be used in vitro and in ...

Stem cells from muscles can repair cartilage

...disease. Treatments and experimental approaches to repair this articular cartilage have achieved limited res...ineered with a therapeutic protein in an effort to repair articular cartilage defects in rats. Led by Johnny Huard, PhD, director of the Growth and Developme...

Bones from blood: Scientists aim to break new ground on fractures

...ructures from cord blood stem cells for use in the repair of bone defects and fractures. The three-year ?.5...able, it might be used for cell-based therapies to repair bone defects and fractures. Ultimately, bone structures developed in this way could be used to make ...

Clawed frog helps Fanconi anemia research make leaps

...esult of a defect in the Fanconi genes' ability to repair DNA damage. Hoatlin said there are many advantages to using the frogs' eggs, instead of human cells, to study Fanconi anemia. "In human cells, most of the Fanconi proteins are hard to detect, so you have to grow millions of cells over long period...

Liver cancer linked to cellular repair pathway

...nior author on the study. The liver's attempts to repair itself and regenerate new tissue after injury can ...ured badly, it uses some of the same mechanisms to repair itself as a fetus uses in growing a liver," Diehl said. The Hedgehog pathway is also linked to cert...

Tiny polyps gorge themselves to survive coral bleaching

...han five-fold, allowing it not only to survive and repair but also replenish its internal energy reserves. "We think that this means that coral like Montipora can switch how it gets its food so that it can sustain itself in a bleached state much longer than can corals like Porites," she said. "While bleac...

New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease

...ar improvement in the animal's kidney function and repair of the glomerular architecture defects. "These re...that bone-marrow-derived stem cells can be used to repair extracellular/basement membrane defects, and according to Kalluri, the researchers' next step will b...

Mayo Clinic collaboration discovers protein amplifies DNA injury signals

... MDC1 amplifies weak DNA injury signals so genetic repair can begin. Once amplified, even low-level damage s...ecome strong enough to activate the cell's natural repair processes while the injury is most tractable to repair. How this "distress call" was communicated ...

Novel molecular 'signature' marks DNA of embryonic stem cells

...rdinary cells are so limited in their abilities to repair or replace damaged cells. "This is an entirely new and unexpected discovery," said Brad Bernstein, lead author of the study, assistant professor at Massachusetts General Hospital and Harvard Medical School, and a researcher in the Chemical Biology p...

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