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Tag: "repair" at biology news

Scientists identify genetic pathways essential to RNA interference

...d with the regulation of DNA itself, including the repair of DNA damage. "These new steps indicate there is more to RNAi than RNA destruction," says Kim. "And the connection to DNA damage pathways, which was totally unexpected, suggests a potential connection between RNAi and the control of cell division in...

Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells

... from adult bone marrow, and cord blood stem cells repair deficiencies in both the central and peripheral nervous systems, said Kurtzberg. Thus, disease progression stabilizes about 2 to 4 months earlier in patients who receive cord blood compared to those who receive adult bone marrow, and huge developmen...

Yeast Network Prevents Damage By Oxygen Radicals

...search (LICR) have identified a key network of DNA repair and cell cycle control genes in yeast that prevents the deleterious effects of ROS. "DNA repair and cell cycle control mechanisms are important guardians against cancerous changes in human cells,"...

Nano-bumps could help repair clogged blood vessels

...iversity have shown that "vascular stents" used to repair arteries might perform better if their surfaces contained "nano-bumps" that mimic tiny features found in living tissues. The researchers already have shown in a series of experiments that bone and cartilage cells in petri dishes attach better to mat...

New understanding of DNA repair may pave way to cancer treatments

...onai. The finding of ATF2's novel function in DNA repair was serendipitous. As Shoichi Takahashi, a postgra...n is central to the cell's ability to initiate DNA repair processes following ionizing irradiation or other exposures that cause breaks in DNA. A likely way i...

Brain-injury rehabilitation depends on acetylcholine circuitry

...d by James Conner and Mark Tuszynski in the Neural repair Group at UCSD have discovered. Their finding in rats could help enhance rehabilitation to recover from such injuries by leading to the development of drugs or other treatments to enhance the "cholinergic system." The researchers said that their find...

NYU and MSKCC research provides model for understanding chemically induced cancer initiation

...ese lesions by DNA transcription, replication, and repair enzymes," said NYU's Geacintov. "Because environm...essing of such carcinogen-damaged p53 genes by DNA repair proteins and DNA and RNA polymerases can determine whether these lesions ultimately contribute to th...

Master gene controls healing of skin in fruit flies and mammals

...the genetic system controlling the development and repair of insect cuticle--the outer layer of the body sur...master gene called grainyhead that activates wound repair genes in the cells surrounding an injury in the cuticle of a fly embryo. These wound repair genes th...

Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells

... from adult bone marrow, and cord blood stem cells repair deficiencies in both the central and peripheral nervous systems, said Kurtzberg. Thus, disease progression stabilizes about 2 to 4 months earlier in patients who receive cord blood compared to those who receive adult bone marrow, and huge developmen...

Unchecked DNA replication drives earliest steps toward cancer

...Halazonetis says. "It might be possible to inhibit repair of these DNA breaks, in which case the cancer cells would die." The lead authors on the Nature study are Vassilis G. Gorgoulis and Leandros-Vassilios F. Vassiliou at the University of Athens. In addition to senior author Halazonetis, the Wistar-base...

Breakthrough isolating embryo-quality stem cells from blood

... a new class of regenerative medicine, which could repair apparently permanent damage such as heart disease or Parkinson's. The cells are currently taken from aborted human foetuses, an issue which has led to controversy and opposition in many parts of the world. Any alternative source, such as voluntary ad...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

...es. Even when they do, we have multiple, redundant repair and proofreading mechanisms that would make even t...neous mutations will occur -- mistakes that escape repair and become part of the DNA of the cell in which they occur. Scientists have generally thought that s...

Young Blood Revives Aging Muscles, Stanford Researchers Find

...work showing that old muscles have the capacity to repair themselves but fail to do so. Rando and his group ... a general phenomenon that a person's inability to repair tissues with age-whether it's muscle, liver, skin or brain-is a matter of the regenerative cell's en...

Natural Killers Could Lead to New Hepatitis Treatments

...the invading microorganism and may also facilitate repair of the damage.?/p> In other experiments, the researchers explored the role of the CXCR6 receptor in the NKT cell's behavior. Receptors are protein sensors that nestle in the membranes of cells and detect external signaling molecules called ligand...

Researchers pioneer new gene therapy technique using natural repair process

...nline in Nature. By artificially initiating a DNA repair process known as homologous recombination, Dr. Mat...ation for division, and uses them as a template to repair the break in the DNA strands. In the new gene therapy technique, researchers took advantage of homo...

Function of new cancer genes discovered

...malignant tumours at a young age, because the cell repair system is incapble of detaching two linked DNA strands. FANCD2 is a protein responsible for the repair of this DNA damage. The protein is linked to a second protein, ubiquitin, when the cell detects that...

Tsunami-damaged coral reefs should be left to recover naturally, say scientists

...ould be very careful not to commit funds to costly repair programmes that may have little long-term effect. ...rom the reefs would be sufficient to allow them to repair themselves. Only in areas where corals were more or less wiped out and no healthy reefs remained nea...

Cancer related gene p53 not regulated as indicated by previous tissue culture research

...y functional when needed to halt the cycle cell to repair DNA damage or to induce apoptosis. "It came as a complete surprise. We even used a system that would have allowed us to switch on the modified p53 protein at will because we feared that the mice might not be viable and would die during early embryon...

Circulating stem cells play small role in lung repair

... and female chromosomal differences to analyze the repair process in lung transplant patients. Reporting in... could be augmented to play a greater role in lung repair ?and people are looking at ways to do that. We found that the bulk of stem cell contribution to the ...

Candida albicans Genome Fully Annotated

... and female chromosomal differences to analyze the repair process in lung transplant patients. Reporting in... could be augmented to play a greater role in lung repair ?and people are looking at ways to do that. We found that the bulk of stem cell contribution to the ...

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