A gene's first 'kiss' sets off that affair known as puberty
...cal messages. Inside the hypothalamus, nerve cells release GnRH in a 'round-the-clock,' pulsatile fashion. Wi... yet to be identified in humans, help control GnRH release in primates." Besides learning that GPR54 and KiSS-1 are expressed inside the hypothalamus of prima...Growth in the sea comes down to a struggle for iron
...hat it (the molecule) is like a magic bullet. They release it, it binds iron, and then only they have the key to unlock it and get the iron out of it. "Now in reality it's warfare. In some cases other bacteria have figured out ways to get the iron from molecules that they didn't produce. So, they can pirate ...Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
... bonemarrow donors to stimulate the bone marrow to release stem cells; andin patients who have had a bone marrow transplant to increase thenumber of white blood cells. It is still considered experimental,however, for use to increase the level of EPCs in patients withperipheral vascular disease.The investigat...Timing is everything: First step in protein building revealed
... the machinery from getting started. Only afterits release from the complex can the ribosome start making pro...en eIF1 was released from the ribosome, or thatits release might serve an important purpose, so this was a completelyunexpected result," says graduate student ...Researchers Uncover Key Step In Manufacture of Memory Protein
... fuse with the cell’s outer membrane, open up, and release mBDNF. During their research, Dr. Loh and her colleagues observed mice genetically incapable of producing CPE. In these mice, proBDNF could not be delivered into the lipid raft-rich vesicles for conversion to mBDNF. Instead, it appeared to leak out ...Scientists Replicate Hepatitis C Virus in Laboratory
... viral life cycle ?viral replication, assembly and release from host cells. Another HCV model system is needed to show the beginning stages of the viral life cycle ?viral entry into host cells and viral activity in the host cell before replication. “With this cell-based system, we can screen compounds with ...The secret to longevity in tubeworms
... to propose that L. luymesi also uses its roots to release sulfate back to the microbial consortia from which it draws its sulfide. Without this return of sulfate, the model predicts an average lifespan of only 39 years in a colony of 1,000 individuals; with it, survival increases to over 250 years, matching...New Technique for Tracking Gene Regulators
...ers.After isolating the CREB-bound fragments, they release the CREB andthen cut the DNA with a “restriction?enzyme that recognizes aparticular nucleotide base sequence, CATG. Further manipulation of thecut ends allows them to isolate 20-base-long-fragments, or “tags,?ineach direction from these cut sites. Th...Research on Worms Yields Clues on Aging
...t the function of sensory neurons thatregulate the release of an insulin-like hormone. "Sensory inputs fromthe outside regulate the level of insulin signaling inside the body,which then in turn regulates longevity in the worms," Kornfeld says.Testing the anticonvulsants on longer-lived mutant worms, theresea...Improved Outcomes Releases GeneLinker(TM) Gold and Platinum Version 4.6
...mproved Outcomes Software (IOS) todayannounced the release of GeneLinker(TM) Gold and Platinum 4.6, newversio...ncluding confidence values).This is also the first release of GeneLinker by Improved OutcomesSoftware Inc. (following Predictive Patterns Software Inc.'s merge...U of M researcher examines newly emerging deadly disease
...n in these patients resulted from massive cytokine release induced by the S. aureus strains. ...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
...M.D. The injectable treatment puts a brake on the release of a key chemical from cells involved in cat allergy reactions. That chemical, histamine, brings on allergy symptoms such as sneezing, wheezing, itching, watery eyes, and sometimes asthma. When a cat-allergic person touches or inhales a protein found...Sea skate experiment sheds light on human cell transport
...kes place. This activates the gates, which open to release excess water along with salts and other organic material. The researchers made their discovery by using a plant-based substance to block an enzyme that causes phosphorylation. The result: The gates wouldn't open. These findings are published in the ...Scientists collaborate to assess health of global environment
...aspects of the assessment will follow this month's release of the global synthesis report. A report on global...se studies In September, the assessment team will release five technical reports totaling nearly 2,500 pages and focusing on the ties between ecosystems and h...Needling Chromosomes Reveals Cell Division Secret
... to balance their adhesion to oneanother and their release during cell division. Their work wassponsored by the National Institutes of Health. Chromosomes are thetiny fiber structures in the cell that house its genes. They replicateand separate in the process of cell division. The exquisite management of ad...In the sea slug's defense against lobsters, confusion is key
...piny lobsters, sea slugs (also known as sea hares) release an inky secretion, termed ink and opaline, from a pair of glands. The new findings show that Aplysia's defensive secretion includes a variety of chemicals that together comprise a multi-pronged attack on the predator's nervous system, resulting in th...New research questions basic tenet of neuron function
...ptic vesicles that sequester neurotransmitters and release them when needed into the synapse, or space betwee...other neurons. It is known that synaptic vesicles release their neurotransmitters in two different "modes" ?one when the neuron is stimulated and actively rel...Critical role in programmed cell death identified
...cing energy to fuel cell processes, also appear to release molecules that set the cell death program in motion. While their activity in mammalian cell death was known, mitochondrial involvement in worms had not previously been shown. The new work, led by Dr. Barbara Conradt, assistant professor of genetics ...Scientists identify genetic pathways essential to RNA interference
... the journal Science and is receiving early online release on the Science Express website at http://www.sciencexpress.org. "The gene activation produced by RNAi is exquisitely specific, which gives it enormous potential for therapeutic application," says Gary Ruvkun, PhD, of the MGH Department of Molecular ...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
... Sciences Institute ("MSI") , announced today the release of a new approach to simulation of intracellularbiochemical networks in the January 2005 edition of NatureBiotechnology.The research article, entitled "Automatic generation of cellular reaction networks with Moleculizer 1.0" (pdf) describes MSI's di...